MCQOPTIONS
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MCQOPTIONS
This section includes 199 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Gain of electrons can be termed as |
| A. | Metabolism |
| B. | Anabolism |
| C. | Oxidation |
| D. | Reduction |
| Answer» E. | |
| 2. |
The major factor(s) determining whether glucose is oxidized by aerobic or anaerobic glycolysis is/are |
| A. | Ca⁺² |
| B. | FADH₂ |
| C. | NADH and the ATP/ADP ratio |
| D. | Presence of high AMP |
| Answer» D. Presence of high AMP | |
| 3. |
Cleavage of Fructose 1, 6-biophosphate yields |
| A. | Two aldoses |
| B. | Two ketoses |
| C. | An aldose and a ketose |
| D. | Only a ketose |
| Answer» D. Only a ketose | |
| 4. |
Formation of one molecule of glucose from pyruvate requires |
| A. | 4 ATP, 2 GTP and 2 NADH |
| B. | 3 ATP, 2 GTP and 2 NADH |
| C. | 4 ATP, 1 GTP and 2 NADH |
| D. | 2 ATP, 2 GTP and 2 NADH |
| Answer» B. 3 ATP, 2 GTP and 2 NADH | |
| 5. |
Maltose hydrolysis yields |
| A. | D-galactose and D-glucose |
| B. | 2-Dglucose |
| C. | n-Dglucose |
| D. | 2-Dfructose |
| Answer» C. n-Dglucose | |
| 6. |
Which of the following is false about acetyl-coA? |
| A. | It is a thioester |
| B. | It has a large, negative standard free energy of hydrolysis |
| C. | It contains phosphorous atom in the position occupied by an oxygen atom in oxygen esters |
| D. | It contains sulfur atom in the position occupied by an oxygen tom in oxygen esters |
| Answer» D. It contains sulfur atom in the position occupied by an oxygen tom in oxygen esters | |
| 7. |
Glucagon is released from |
| A. | Muscle |
| B. | Pancreas |
| C. | Kidneys |
| D. | Epithelial tissues |
| Answer» C. Kidneys | |
| 8. |
If ∆G‘° of the reaction A → B is -40kJ/mol under standard conditions then the reaction |
| A. | Will never reach equilibrium |
| B. | Will not occur spontaneously |
| C. | Will proceed at a rapid rate |
| D. | Will proceed from left to right spontaneously |
| Answer» E. | |
| 9. |
The end products in ethanol fermentation are |
| A. | Ethanol and CO₂ |
| B. | Ethanol and O₂ |
| C. | Ethanol, H₂ and CO₂ |
| D. | Ethanol, O₂ and CO₂ |
| Answer» B. Ethanol and O₂ | |
| 10. |
Which of the following enzyme is present in saliva? |
| A. | Hexokinase |
| B. | Alpha amylase |
| C. | Fructokinase |
| D. | Triose kinase |
| Answer» C. Fructokinase | |
| 11. |
The compounds responsible for coordinated regulation of glucose and glycogen metabolism are |
| A. | NADH |
| B. | NAD⁺ |
| C. | Acetyl co-A |
| D. | Fructose 2, 6-bisphosphate |
| Answer» E. | |
| 12. |
Which of the following enzymes is involved in fatty acid synthesis? |
| A. | Hexokinase II |
| B. | Hexokinase IV |
| C. | PFK-2/FBPase-2 |
| D. | Pyruvate dehydrogenase |
| Answer» E. | |
| 13. |
Which of the following is not an important precursor of glucose in animals? |
| A. | Lactate |
| B. | Pyruvate |
| C. | Glycerol |
| D. | Glucose 6-phosphate |
| Answer» E. | |
| 14. |
Oxaloacetate is reduced to malate by |
| A. | Pyruvate carboxylase |
| B. | Malate dehydrogenase |
| C. | Pyruvate kinase |
| D. | Phosphofructokinase-1 |
| Answer» C. Pyruvate kinase | |
| 15. |
Manganese is needed for |
| A. | normal bone structure |
| B. | reproduction and functioning of central nervous system |
| C. | both (a) and (b) |
| D. | muscle strengthening |
| Answer» D. muscle strengthening | |
| 16. |
Water does a nucleophilic attack on phosphate monoester producing |
| A. | Phosphorous chloride |
| B. | Phosphorous sulfide |
| C. | Inorganic phosphate |
| D. | Organic phosphate |
| Answer» D. Organic phosphate | |
| 17. |
Glycogen synthase a is activated by |
| A. | Phosphorylation catalyzed by GSK3 |
| B. | Dephosphorylation catalyzed by GSK3 |
| C. | Phosphorylation catalyzed by pyruvate kinase |
| D. | Phosphorylation catalyzed by pyruvate carboxylase |
| Answer» B. Dephosphorylation catalyzed by GSK3 | |
| 18. |
Which of the following statements is false about ATP hydrolysis? |
| A. | It is highly exergonic |
| B. | Activation energy is relatively high |
| C. | ∆G‘°=-30.5kJ/mol |
| D. | ∆G‘°=30.5kJ/mol |
| Answer» E. | |
| 19. |
Phosphoryl groups are derivatives of |
| A. | Phosphorous acid |
| B. | Phosphoric acid |
| C. | Acetic acid |
| D. | Citric acid |
| Answer» C. Acetic acid | |
| 20. |
Wilson's disease is an example of __________ and Menkes' syndrome is an example of __________ . |
| A. | zinc deficiency; zinc toxicity |
| B. | zinc toxicity; zinc deficiency |
| C. | copper deficiency; copper toxicity |
| D. | copper toxicity; copper deficiency |
| Answer» E. | |
| 21. |
What is the relation between elasticity coefficient, flux coefficient and response coefficient? |
| A. | R = C.ε |
| B. | R = C⁄ε |
| C. | R = ε⁄C |
| D. | ε = C.R |
| Answer» B. R = C⁄ε | |
| 22. |
Which of the following statements is correct about oxidative pentose phosphate pathway? |
| A. | It generates NADH |
| B. | It oxidizes NADPH to NADP⁺ |
| C. | The pathway supplies ribose 5-phosphate and NADPH in the quantities the cell requires |
| D. | Glucose 6-phosphatase catalyzes the rate limiting reaction of the pathway |
| Answer» D. Glucose 6-phosphatase catalyzes the rate limiting reaction of the pathway | |
| 23. |
The second control point in gluconeogenesis is the reaction catalyzed by |
| A. | Pyruvate kinase |
| B. | Pyruvate dehydrogenase |
| C. | FBPase-1 |
| D. | PFK-1 |
| Answer» D. PFK-1 | |
| 24. |
The phosphate groups used during glycolysis are |
| A. | Organic |
| B. | Inorganic |
| C. | Neutral |
| D. | None of the mentioned |
| Answer» C. Neutral | |
| 25. |
Which is an example for electromagnetic to electrical energy conversion that occurs in living organisms |
| A. | ATP-driven muscle contraction |
| B. | ATP-dependent photon emission in fireflies |
| C. | light-induced electron flow in chloroplasts |
| D. | ATP-driven active transport across a membrane |
| Answer» D. ATP-driven active transport across a membrane | |
| 26. |
The relationship between K‘eq and ∆G‘° is |
| A. | ∆G‘° = RTlnK‘eq |
| B. | ∆G‘° = -RTK‘eq |
| C. | ∆G‘° = RK‘eq |
| D. | ∆G‘° = -RK‘eq |
| Answer» C. ∆G‘° = RK‘eq | |
| 27. |
Flux control coefficient measures the |
| A. | Steady state change |
| B. | pH change |
| C. | Temperature change |
| D. | Hormonal change |
| Answer» B. pH change | |
| 28. |
The first step in the payoff phase of glycolysis is |
| A. | Reduction of 1, 3-bisphosphoglycerate to glyceraldehyde 3-phosphate |
| B. | Oxidation of glyceraldehyde 3-phosphate to 1, 3-bisphosphoglycerate |
| C. | Reversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate |
| D. | Irreversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate |
| Answer» C. Reversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate | |
| 29. |
Which group is most often affected with copper deficiency? |
| A. | Elderly woman |
| B. | Alcoholics |
| C. | Active toddlers with limited |
| D. | Preterm infants food variety |
| Answer» B. Alcoholics | |
| 30. |
Which of the following carbohydrate is effective in promoting the calcium absorption? |
| A. | Lactose |
| B. | Maltose |
| C. | Sucrose |
| D. | Xylose |
| Answer» B. Maltose | |
| 31. |
Which is an example for chemical to mechanical energy conversion that occurs in living organisms? |
| A. | ATP-driven muscle contraction |
| B. | ATP-dependent photon emission in fireflies |
| C. | light-induced electron flow in chloroplasts |
| D. | ATP-driven active transport across a membrane |
| Answer» B. ATP-dependent photon emission in fireflies | |
| 32. |
Which of the following statements is false about gluconeogenesis? |
| A. | From the hydrolysis of tri-acyl-glycerol, fatty acids can be used as a carbon source |
| B. | From red blood cells, lactate can be used as a carbon source |
| C. | From the hydrolysis of tri-acyl-glycerol, glycerol is converted to glucose in gluconeogenesis |
| D. | From muscle vigorous muscle activity, lactate can be used as a carbon source |
| Answer» B. From red blood cells, lactate can be used as a carbon source | |
| 33. |
An expression for the experimentally determined change in flux through a pathway in response to a regulatory hormone or second messenger |
| A. | Response coefficient |
| B. | Elasticity coefficient |
| C. | Flux control coefficient |
| D. | Metabolic control |
| Answer» B. Elasticity coefficient | |
| 34. |
Which of the following is a potent regulator of glycolysis and gluconeogenesis? |
| A. | Fructose 2, 6-bisphosphate |
| B. | Fructose 1, 6-bisphosphate |
| C. | Fructose 6-phosphate |
| D. | Glucose 1, 6-bisphosphate |
| Answer» B. Fructose 1, 6-bisphosphate | |
| 35. |
Three reactions of glycolysis are so exergonic, which are not catalyzed by |
| A. | Hexokinase |
| B. | PFK-1 |
| C. | Pyruvate kinase |
| D. | Pyruvate dehydrogenase |
| Answer» E. | |
| 36. |
Loss of electrons can be termed as |
| A. | Metabolism |
| B. | Anabolism |
| C. | Oxidation |
| D. | Reduction |
| Answer» D. Reduction | |
| 37. |
Which of the following is involved in triacylglycerol synthesis? |
| A. | Hexokinase II |
| B. | Acyl co-A glycerol transferases |
| C. | PFK-2/FBPase-2 |
| D. | Pyruvate dehydrogenase |
| Answer» C. PFK-2/FBPase-2 | |
| 38. |
For a reaction if ∆G° is positive, then |
| A. | The products will be favored |
| B. | The reactants will be favored |
| C. | The concentration of the reactants and products will be equal |
| D. | All of the reactant will be converted to products |
| Answer» C. The concentration of the reactants and products will be equal | |
| 39. |
An endergonic reaction |
| A. | Proceeds spontaneously |
| B. | Does not require activation energy |
| C. | Releases energy |
| D. | Requires energy |
| Answer» E. | |
| 40. |
Which out of the following statements is true about regulation of metabolic pathway? |
| A. | Most of the metabolic pathways are regulated |
| B. | Most of the metabolic pathways are not regulated |
| C. | Regulation of metabolic pathways always involves changing the amount of enzymes |
| D. | Metabolic regulation always depends on control by hormones |
| Answer» B. Most of the metabolic pathways are not regulated | |
| 41. |
Which out of the following enzymes can utilize both NAD⁺ and NADP⁺ as a coenzyme? |
| A. | Glutamate dehydrogenase |
| B. | Alcohol dehydrogenase |
| C. | Aldehyde dehydrogenase |
| D. | Glycerol-3-P ddehydrogenase |
| Answer» B. Alcohol dehydrogenase | |
| 42. |
Which of the following enzyme catalyzes the first step in the catabolism of ethanol? |
| A. | Alcohol dehydrogenase |
| B. | Lactate dehydrogenase |
| C. | Glutamate dehydrogenase |
| D. | Malate dehydrogenase |
| Answer» B. Lactate dehydrogenase | |
| 43. |
Which out of the following has the highest redox potential? |
| A. | NAD |
| B. | FMN |
| C. | FAD |
| D. | O₂ |
| Answer» E. | |
| 44. |
Enzyme involved in the pathway of synthesis of acetyl-coA |
| A. | Hexokinase |
| B. | Pyruvate decarboxylase |
| C. | Pyruvate dehydrogenase |
| D. | Pyruvate kinase |
| Answer» D. Pyruvate kinase | |
| 45. |
High concentration of glucose 6-phosphate is inhibitory to |
| A. | Hexokinase |
| B. | Pyruvate kinase |
| C. | Glucokinase |
| D. | Phosphofructokinase-1 |
| Answer» B. Pyruvate kinase | |
| 46. |
Which of the following statements is true regarding acetyl co-A? |
| A. | It stimulates pyruvate dehydrogenase |
| B. | It stimulates pyruvate carboxylase |
| C. | It inhibits pyruvate carboxylase |
| D. | It stimulates hexokinase |
| Answer» C. It inhibits pyruvate carboxylase | |
| 47. |
Gluconeogenesis responds to which of the following? |
| A. | Hormonal control |
| B. | pH control |
| C. | Temperature control |
| D. | Blood control |
| Answer» B. pH control | |
| 48. |
Which one out of the following is not a NAD⁺ requiring enzyme? |
| A. | Lactate dehydrogenase |
| B. | Pyruvate dehydrogenase complex |
| C. | Maltate dehydrogenase |
| D. | Acyl co-A dehydrogenase |
| Answer» E. | |
| 49. |
Which of the following statements about redox potential is false? |
| A. | NADH/NAD⁺ redox pair has the least redox potential |
| B. | Oxygen/H₂O redox pair has the highest redox potential |
| C. | The components of electron transport chain are organized in terms of their redox potential |
| D. | The redox potential of a system is usually compared with the potential of the hydrogen electrode |
| Answer» B. Oxygen/H₂O redox pair has the highest redox potential | |
| 50. |
Some regulated enzymes rebalance the level of metabolites in response to the change in flux, this activity is |
| A. | Regulation |
| B. | Control |
| C. | Metabolism |
| D. | Anabolism |
| Answer» B. Control | |