MCQOPTIONS
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MCQOPTIONS
This section includes 29 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Following RNAse are used for RNA processing except one, mark that? |
| A. | RNAse P |
| B. | SnRNP |
| C. | RNAse E |
| D. | RNAse G |
| Answer» C. RNAse E | |
| 2. |
Choose the INCORRECT statement about 5’ cap. |
| A. | Recognized by the transport protein |
| B. | Provide stability to RNA |
| C. | Participate in the translation initiation |
| D. | Increase the life span of RNA |
| Answer» E. | |
| 3. |
Which of the following form 5’cap? |
| A. | 5’ ——> 5’ PPP linkage |
| B. | 5’ ——> 3’ PPP linkage |
| C. | 3’ ——> 3’ PPP linkage |
| D. | 3’ ——> 5’ NPP linkage |
| Answer» B. 5’ ——> 3’ PPP linkage | |
| 4. |
The process of modification of pre mRNA is known as___________ |
| A. | Replication |
| B. | DNA repair |
| C. | Translation |
| D. | RNA processing |
| Answer» E. | |
| 5. |
Which type of splicing reaction requires a guanine nucleoside or nucleotide cofactor that is not used as a source of energy? |
| A. | Spliceosomal |
| B. | Group I |
| C. | Group II |
| D. | Group IV |
| Answer» C. Group II | |
| 6. |
The largest class of introns which are found in nuclear mRNA primary transcript is? |
| A. | Spliceosomal introns |
| B. | Group I introns |
| C. | Group II introns |
| D. | Group IV introns |
| Answer» B. Group I introns | |
| 7. |
Which one of the following best describes the cap modification of eukaryotic mRNA? |
| A. | Modified guanine nucleotide added to the 3’ end of the transcript |
| B. | Modified guanine nucleotide added to the 5’ end of the transcript |
| C. | String of adenine nucleotides added to the 3’ end of the transcript |
| D. | String of adenine nucleotides added to the 5’ end of the transcript |
| Answer» C. String of adenine nucleotides added to the 3’ end of the transcript | |
| 8. |
What is the main function of t-RNA? |
| A. | Proof reading |
| B. | Inhibits protein synthesis |
| C. | Identifies amino acids and transport them to ribosomes |
| D. | None of the mentioned |
| Answer» D. None of the mentioned | |
| 9. |
80S eukaryotic ribosome is the complex of ____________ |
| A. | 60S and 40S |
| B. | 40S and 20S |
| C. | 60S and 50S |
| D. | 30S and 20S |
| Answer» B. 40S and 20S | |
| 10. |
70S prokaryotic ribosome is the complex of ____________ |
| A. | 30S + 50S |
| B. | 30S + 40S |
| C. | 20S + 60S |
| D. | 20S + 30S |
| Answer» B. 30S + 40S | |
| 11. |
Which is the first nucleic acid synthesizing enzyme discovered? |
| A. | Polynucleotide phosphorylase |
| B. | DNA polymerase |
| C. | RNA polymerase |
| D. | DNA ligase |
| Answer» B. DNA polymerase | |
| 12. |
Which of the following is an incorrect statement about m-RNA? |
| A. | Cap is added to the 5’ end |
| B. | Introns are removed and exons are spliced together |
| C. | Histone mRNAs lack 5’ cap |
| D. | Poly-A tail is added to the 3’ end |
| Answer» C. Histone mRNAs lack 5’ cap | |
| 13. |
WHICH_TYPE_OF_SPLICING_REACTION_REQUIRES_A_GUANINE_NUCLEOSIDE_OR_NUCLEOTIDE_COFACTOR_THAT_IS_NOT_USED_AS_A_SOURCE_OF_ENERGY??$ |
| A. | Spliceosomal |
| B. | Group I |
| C. | Group II |
| D. | Group IV |
| Answer» C. Group II | |
| 14. |
FOLLOWING_RNASE_ARE_USED_FOR_RNA_PROCESSING_EXCEPT_ONE,_MARK_THAT??$ |
| A. | RNAse P |
| B. | SnRNP |
| C. | RNAse E |
| D. | RNAse G |
| Answer» C. RNAse E | |
| 15. |
The largest class of introns which are found in nuclear mRNA primary transcript i? |
| A. | Spliceosomal introns |
| B. | Group I introns |
| C. | Group II introns |
| D. | Group IV introns |
| Answer» B. Group I introns | |
| 16. |
Name the term where a single pre-mRNA is processed into a number of products? |
| A. | Alternate splicing |
| B. | Polyadenylation |
| C. | Capping |
| D. | Intron removal |
| Answer» B. Polyadenylation | |
| 17. |
One of the following best describes the cap modification of eukaryotic mRN? |
| A. | Modified guanine nucleotide added to the 3’ end of the transcript |
| B. | Modified guanine nucleotide added to the 5’ end of the transcript |
| C. | String of adenine nucleotides added to the 3’ end of the transcript |
| D. | String of adenine nucleotides added to the 5’ end of the transcript |
| Answer» C. String of adenine nucleotides added to the 3‚Äö√Ñ√∂‚àö√ë‚àö¬• end of the transcript | |
| 18. |
Name the type of intron which needs spliceosomes to be spliced? |
| A. | Group I intron |
| B. | Group IV intron |
| C. | Nuclear intron |
| D. | Group II intron |
| Answer» D. Group II intron | |
| 19. |
The main function of t-RNA is |
| A. | Proof reading |
| B. | Inhibits protein synthesis |
| C. | Identifies amino acids and transport them to ribosomes |
| D. | None |
| Answer» D. None | |
| 20. |
Which of the following group of introns form stable lariat structure? |
| A. | Group I intron |
| B. | Group II intron |
| C. | Nuclear intron |
| D. | Group III intron |
| Answer» C. Nuclear intron | |
| 21. |
Choose the INCORRECT statement about 5’ cap.$ |
| A. | Recognized by the transport protein |
| B. | Provide stability to RNA |
| C. | Participate in the translation initiation |
| D. | Increase the life span of RNA |
| Answer» E. | |
| 22. |
70S prokaryotic ribosome is the complex of |
| A. | 30S + 50S |
| B. | 30S + 40S |
| C. | 20S + 60S |
| D. | 20S + 30S |
| Answer» B. 30S + 40S | |
| 23. |
Which of the following form 5’cap?$ |
| A. | 5’ ——> 5’ PPP linkage |
| B. | 5’ ——> 3’ PPP linkage |
| C. | 3’ ——> 3’ PPP linkage |
| D. | 3’ ——> 5’ NPP linkage |
| Answer» B. 5‚Äö√Ñ√∂‚àö√ë‚àö¬• ‚Äö√Ñ√∂‚àö√ë‚àö√Ü‚Äö√Ñ√∂‚àö√ë‚àö√Ü> 3‚Äö√Ñ√∂‚àö√ë‚àö¬• PPP linkage | |
| 24. |
The first nucleic acid synthesizing enzyme discovered is |
| A. | Polynucleotide phosphorylase |
| B. | DNA polymerase |
| C. | RNA polymerase |
| D. | DNA ligase |
| Answer» B. DNA polymerase | |
| 25. |
Which of the following is NOT the step of mRNA processing? |
| A. | 5’ capping |
| B. | Splicing of introns |
| C. | Polyadenylation |
| D. | RNA silencing |
| Answer» E. | |
| 26. |
Incorrect statement about m-RNA |
| A. | Cap is added to the 5’ end |
| B. | Introns are removed and exons are spliced together |
| C. | Histone mRNAs lack 5’ cap |
| D. | Poly-A tail is added to the 3’ end |
| Answer» C. Histone mRNAs lack 5‚Äö√Ñ√∂‚àö√ë‚àö¬• cap | |
| 27. |
In eukaryotes, transcription and translation take place in the same compartment. |
| A. | True |
| B. | False |
| Answer» C. | |
| 28. |
Which of the following is not involved in the post transcriptional processing of t-RNA? |
| A. | Base modulation |
| B. | Attachment of CCA arm |
| C. | Splicing |
| D. | Attachment of poly-A tail |
| Answer» E. | |
| 29. |
Which of the following statements regarding splicing in eukaryotes is correct? |
| A. | Several reactions in the splicing process involve hydrolysis of ATP |
| B. | Exons are spliced out and introns are retained in the mature mRNA transcript |
| C. | Splicing takes place in the cytosol |
| D. | Small nuclear RNAs are retained in the mature mRNA transcript |
| Answer» B. Exons are spliced out and introns are retained in the mature mRNA transcript | |