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This section includes 58 Mcqs, each offering curated multiple-choice questions to sharpen your Bachelor of Pharmacy (BDot Pharma) knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
In the determination of size, shape and structure of colloidal particles, which one of the following CAN NOT be used? |
| A. | electron microscope |
| B. | instrument measuring light scattering |
| C. | Langmuir film balance |
| D. | ultramicroscope |
| Answer» E. | |
| 2. |
Which quality of the dispersed phase is responsible for the increased viscosity of a hydrophilic colloidal dispersion? |
| A. | charge |
| B. | shape |
| C. | size |
| D. | surface area |
| Answer» E. | |
| 3. |
If kinetic energy of interaction is about 25 kT (Where k is gas constant), the system can be considered to have: |
| A. | deflocculated state |
| B. | long half life |
| C. | short half life |
| D. | weak attractiton forces |
| Answer» C. short half life | |
| 4. |
Which one of the following properties is extensively applied for determining the molecular weight of polymer? |
| A. | depression of freezing point |
| B. | elevation of boiling point |
| C. | lowering of vapour pressure |
| D. | osmotic pressure |
| Answer» E. | |
| 5. |
The continuous collisions between the colloidal particles and molecules of dispersion medium produce zigzag movement of colloidal particles which is known as |
| A. | Brownian movement |
| B. | Tyndall effect |
| C. | Diffusion |
| D. | Sedimentation |
| Answer» B. Tyndall effect | |
| 6. |
.......... is the method accountable for the development of stable dispersion of colloidal particles in dispersion medium. |
| A. | Coacervation |
| B. | Peptization |
| C. | Flocculation |
| D. | Coagulation |
| Answer» C. Flocculation | |
| 7. |
An o/w microemulsion is prepared using a hydrophilic surfactant. The appearance of the microemulsion is: |
| A. | intense white |
| B. | milky white |
| C. | translucent |
| D. | tr |
| Answer» B. milky white | |
| 8. |
In exothermic Reaction, if we increase the temperature in the exothermic reaction the rate of reaction will......... |
| A. | Increases |
| B. | Decrease |
| C. | Remains constant |
| D. | None of the above |
| Answer» C. Remains constant | |
| 9. |
Emulsions are defined as thermodynamically unstable systems. The events that follow sequentially towards instability are: |
| A. | coalescence, breaking, creaming and flocculation |
| B. | coalescence, flocculation, creaming and breaking |
| C. | flocculation, creaming, breaking and coalescence |
| D. | flocculation, creaming, coalescence and breaking |
| Answer» E. | |
| 10. |
............ exists when dispersed solid particles in a suspension retain change in relation their adjoining liquid medium. |
| A. | Surface area |
| B. | Surface potential |
| C. | Surface volume |
| D. | None of the above |
| Answer» C. Surface volume | |
| 11. |
The density of the dispersed phase is more than that of the dispersion medium. According to the Stokes' equation, the creaming is: |
| A. | at the center of the emulsion |
| B. | in both the directions |
| C. | in downward direction |
| D. | in upward direction |
| Answer» D. in upward direction | |
| 12. |
When an emulsion is exposed to ultra-violet radiations. If the continuous fluorescence is observed under microscope, then it is_____________ type emulsion. |
| A. | w/o |
| B. | o/w |
| C. | microemulsion |
| D. | Nano emulsion |
| Answer» B. o/w | |
| 13. |
A .......... is a mixture in which one substance of microscopically dispersed insoluble particles is suspended through another substance. |
| A. | Suspension |
| B. | Colloid |
| C. | Emulsion |
| D. | None of the above |
| Answer» B. Colloid | |
| 14. |
The ratio of the sedimentation volume in case of flocculated suspension to the sedimentation volume in case of deflocculated suspension is called |
| A. | Sedimentation volume |
| B. | Degree of flocculation |
| C. | Emulsification volume |
| D. | phase volume ratio |
| Answer» C. Emulsification volume | |
| 15. |
A wetting agent is included in the formulation of a suspension, particularly when the suspended particles: |
| A. | are hydrophobic |
| B. | are more denser than the vehicle |
| C. | are water soluble |
| D. | have lesser interfacial tension |
| Answer» B. are more denser than the vehicle | |
| 16. |
For a flocculated suspension the degree of flocculation is observed to be one. The sedimentation volume is also 1 (one). These values, respectively, indicate the limits: |
| A. | lower and lower |
| B. | lower and upper |
| C. | upper and lower |
| D. | upper and upper |
| Answer» C. upper and lower | |
| 17. |
In case of emulsions, the viscosity immediately after preparation and during storage, respectively, will be: |
| A. | higher and will gradually decrease |
| B. | higher and gradually increase |
| C. | lower and gradually decrease |
| D. | lower and gradually increase |
| Answer» D. lower and gradually increase | |
| 18. |
When cumulative percent frequency on a probability scale is plotted against logarithm of the particle size, 50 percent on the probability scale gives the powder particle diameter of: |
| A. | arithmetic mean |
| B. | arithmetic mode |
| C. | geometric mean |
| D. | harmonic mean |
| Answer» D. harmonic mean | |
| 19. |
While using sedimentation method for size analysis, addition of a deflocculating agent to a suspension is necessary in order to: |
| A. | accelerate the process of sedimentation |
| B. | make the particles spherical |
| C. | prevent the aggregation |
| D. | satisfy Reynolds number |
| Answer» D. satisfy Reynolds number | |
| 20. |
Penicillin G is prepared as a salt of procaine penicillin G. Now the rate of decomposition of penicillin G will be: |
| A. | increased |
| B. | reduced |
| C. | unchanged |
| D. | unpredictable |
| Answer» C. unchanged | |
| 21. |
In the degradation studies of aspirin suspension, the orders observed initially and at the end, respectively, are: - |
| A. | first, second |
| B. | first, zero |
| C. | second, first |
| D. | zero, first |
| Answer» E. | |
| 22. |
...... determines the movement of charged particles via a liquid under the impact of an applied potential difference. |
| A. | Electrophoresis |
| B. | Electrosmosis |
| C. | Surface charge |
| D. | Static movement |
| Answer» B. Electrosmosis | |
| 23. |
When a series of steps are involved in a reaction, the overall rate of a reaction depends upon the rate(s) of: |
| A. | all steps |
| B. | all steps which follow the slowest step |
| C. | all steps which precede the slowest step |
| D. | the slowest step |
| Answer» D. the slowest step | |
| 24. |
A variety of factors would influence the rate of creaming in an emulsion. The factor open to formulation pharmacist is to regulate: |
| A. | density of dispersion medium |
| B. | density of dispersed phase |
| C. | globule size |
| D. | volume of dispersion medium |
| Answer» D. volume of dispersion medium | |
| 25. |
In the study of the rate of a reaction, 100 ml of 0.1 N hydrochloric acid is added to 10 ml methyl acetate for the reaction to occur. The reason for making such a proportion is to make: |
| A. | analysis of degradation is easy |
| B. | reaction to follow first order |
| C. | reaction to proceed slowly |
| D. | reaction to undergo a pseudo first order |
| Answer» E. | |
| 26. |
The integral rate equation for a reaction (in common notation) is written as log C = log Co - (kt/2.303). When a graph is drawn log c vs. t, the slope will be: |
| A. | negative |
| B. | one |
| C. | Positive |
| D. | Zero |
| Answer» B. one | |
| 27. |
When a beam of light is pass through a colloidal solution, the path of light gets illuminated. This phenomenon is known as |
| A. | Brownian movement |
| B. | Diffusion |
| C. | Tyndall effect |
| D. | Donnan effect |
| Answer» D. Donnan effect | |
| 28. |
The phenomenon which involves separation of macromolecular solutions into two liquid layers is called as......... |
| A. | Liquid separation |
| B. | Coagulation |
| C. | Flocculation |
| D. | Coacervation |
| Answer» E. | |
| 29. |
The specific rate constant (k) determined for aspirin hydrolysis in pH 1.0 buffer at 1 mg/ml concentration is 2.0x10-3 min-1 at 25 C. The shelf life of the product is (in minutes): |
| A. | 2.0 |
| B. | 52 |
| C. | 104 |
| D. | 346 |
| Answer» C. 104 | |
| 30. |
In the hydrolysis of sucrose in hydrochloric acid solution, the change in the optical rotation follows the order: |
| A. | pseudofirst |
| B. | pseudo zero |
| C. | second |
| D. | zero |
| Answer» B. pseudo zero | |
| 31. |
A prescription of liquid aspirin preparation contained 6.5 g/100 ml. The solubility of aspirin at 25 C is 0.33 g/100 ml. The order of reaction in the kinetic study is: |
| A. | apparent first |
| B. | apparent zero |
| C. | first |
| D. | second |
| Answer» C. first | |
| 32. |
In chemical kinetics, the rate of a reaction is expressed as (-dc/dt), where dc refers to the concentration. Whose concentration does it refer to? |
| A. | catalyst |
| B. | product |
| C. | reactant |
| D. | solvent medium |
| Answer» D. solvent medium | |
| 33. |
In a chemical reaction, the rate constant is independent of the initial concentration. Which one of them is the order? |
| A. | first |
| B. | second |
| C. | third |
| D. | zero |
| Answer» E. | |
| 34. |
One of the following is NOT a one point viscometer, but can be used for the same purpose. Pick the viscometer of this type. |
| A. | cup and bob |
| B. | falling sphere |
| C. | Ostwald |
| D. | rolling ball |
| Answer» B. falling sphere | |
| 35. |
The time required for the complete degradation of a drug in solution is a finite value. The order of that reaction is: |
| A. | first |
| B. | pseudo first |
| C. | second |
| D. | zero |
| Answer» E. | |
| 36. |
Which of the following properties of a particle significantly affects the physical, chemical and biological properties of the drug? |
| A. | density |
| B. | sedimentation |
| C. | size |
| D. | surface area |
| Answer» E. | |
| 37. |
..........technique is utilized only during determination of order of reaction, when the rate law involved by only single concentration term. |
| A. | The concentration |
| B. | The half of the concentration |
| C. | The square of the concentration |
| D. | None of the above |
| Answer» D. None of the above | |
| 38. |
...........technique is utilized only when the rate law involved by only single concentration term for determination of order of reaction. |
| A. | Half Life Method |
| B. | Graphical Method |
| C. | Initial Rate Method |
| D. | Van't Hoff Differential Method |
| Answer» B. Graphical Method | |
| 39. |
........... is the time necessary for the concentration of the reactant to decrease to 90% of its original concentration. |
| A. | Product life |
| B. | Shelf life |
| C. | Half life |
| D. | None of the above |
| Answer» C. Half life | |
| 40. |
After giving the i.m. injection of procaine penicillin G, the process of forming a depot in the muscle is due to: |
| A. | high yield value |
| B. | low consistency |
| C. | low yield value |
| D. | rapid thixotropic recovery |
| Answer» E. | |
| 41. |
Which of the following expression is correct for the determination of shelf life for a first order decomposition? |
| A. | t1/2 = 0.105/k |
| B. | t90 = 0.693/k |
| C. | t1/2 = 0.693/k |
| D. | t90 = 0.105/k |
| Answer» E. | |
| 42. |
When charcoal powder is dusted on the surface of water, the contact angle (in degrees) that the charcoal exhibits is: |
| A. | zero |
| B. | one |
| C. | 90 |
| D. | 180 |
| Answer» E. | |
| 43. |
According to the Newton's law of viscosity, "The shear stress in flowing fluid is__________ to the rate of shear." |
| A. | Inversely proportional |
| B. | directly proportional |
| C. | Square root |
| D. | Perpendicular |
| Answer» C. Square root | |
| 44. |
For the validity of accelerated stability studies of solution dosage form, the energy of activation should be in the range of (in units of kcal/mole). |
| A. | 0 to 10 |
| B. | 11 to 30 |
| C. | 31 to 50 |
| D. | 51 to 70 |
| Answer» C. 31 to 50 | |
| 45. |
According to International Pharmaceutical Federation, the recommended overages be limited to the maximum percent of: |
| A. | five |
| B. | ten |
| C. | thirty |
| D. | twenty |
| Answer» D. twenty | |
| 46. |
On a product, the label states protect from light . What type of decomposition does the product undergo? |
| A. | carboxylation |
| B. | decarboxylation |
| C. | hydrolysis |
| D. | oxidation |
| Answer» E. | |
| 47. |
When distance between the particle are large, the particles experience attractive force and aggregates are formed. This is known as |
| A. | Primary minimum |
| B. | Potential barrier |
| C. | secondary minimum |
| D. | Interparticle distance |
| Answer» D. Interparticle distance | |
| 48. |
......is the alteration in the shape and the size of a body owing to applied external forces and internal forces. |
| A. | Deformation |
| B. | Formation |
| C. | Conjugation |
| D. | None of the above |
| Answer» B. Formation | |
| 49. |
The molecular weight of dispersed solids in a colloidal system can be determined using an instrument: |
| A. | ultracentrifuge |
| B. | ultrafilters |
| C. | ultramicroscope |
| D. | zeta meter |
| Answer» B. ultrafilters | |
| 50. |
Fisher subsieve sizer is used to determine the surface area of the powder. The surface area is measured based on the change in: |
| A. | light transmission of gas that reaches the detector |
| B. | pressure across the compacted powder |
| C. | thermal conductivity of gas across the powdered pack |
| D. | weight of powder when air is passed through the powdered pack |
| Answer» E. | |