MCQOPTIONS
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MCQOPTIONS
This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Bachelor of Pharmacy (BDot Pharma) knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Compound with good activity and selectivity in screening during drug discovery is known as |
| A. | Hit |
| B. | Lead |
| C. | NDA |
| D. | IND |
| Answer» C. NDA | |
| 2. |
Identification of a new chemical entity as a potential therapeutic agent (From Hit to Lead) is known as |
| A. | Drug discovery |
| B. | Drug development |
| C. | Both of above |
| D. | None of above |
| Answer» B. Drug development | |
| 3. |
What is the name of the process where due to nutritional deficiency an enzyme content is decreased? |
| A. | Altered physiology |
| B. | Repression |
| C. | Non-competitive inhibition |
| D. | Competitive inhibition |
| Answer» B. Repression | |
| 4. |
R (-) Epinephrine shows 3 point of interaction with receptor while S (+)Epinephrine shows 2 point of interaction with receptor. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» B. False | |
| 5. |
What plays a major role in extra-hepatic metabolism and contains CYP3A4 isozyme and P-glycoprotein? |
| A. | Kidney |
| B. | Throat |
| C. | Liver |
| D. | Intestine |
| Answer» D. Intestine | |
| 6. |
Biotransformation of drugs is defined as the conversion from one physical form to another. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» C. none | |
| 7. |
Which of the following is not a common N containing functional groups which undergo reduction reactions? |
| A. | Nitro compounds |
| B. | Azo compounds |
| C. | N-oxide compounds |
| D. | Nitrite compounds |
| Answer» E. | |
| 8. |
Which enzyme is of the utmost importance for the 2nd step in the formation of Glucuronide? |
| A. | Esterase |
| B. | Amidases |
| C. | Transferase |
| D. | UDP-glucuronyl tr |
| Answer» B. Amidases | |
| 9. |
For dissolution of solute in solvent which condition is necessary?1. Solute-solvent interaction should be less than solute-solute and solvent-solvent interaction2. Solute-solvent interaction should equal solute-solute and solvent-solvent interaction3. Solute-solvent interaction should exceed solute-solute and solvent-solvent interaction |
| A. | 1 & 2 |
| B. | 2 & 3 |
| C. | 1 & 3 |
| D. | 1, 2 & 3 |
| Answer» C. 1 & 3 | |
| 10. |
The most important physicochemical properties affecting drug actiona) Partition coefficientb) Solubilityc) Acid base propertiesd) Chemical bondinge) Chelationf) Surface activity |
| A. | All of the above |
| B. | A and B both |
| C. | D and E both |
| D. | C and F both |
| Answer» B. A and B both | |
| 11. |
What cytochrome P450 isozyme is most abundantly expressed in the human liver and intestines? |
| A. | CYP1A1 |
| B. | CYP3A4 |
| C. | CYP2C9 |
| D. | CYP2D6 |
| Answer» C. CYP2C9 | |
| 12. |
What injection is administered directly into systemic circulation causing rapid distribution? |
| A. | Intramuscular |
| B. | Intravenous |
| C. | Intracerebral |
| D. | Intraspinal |
| Answer» C. Intracerebral | |
| 13. |
In comparison with children and young adults, elderly adults tend to have a reduced capacity to metabolize drugs. |
| A. | True |
| B. | False |
| C. | none |
| D. | all |
| Answer» B. False | |