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This section includes 16 Mcqs, each offering curated multiple-choice questions to sharpen your Analytical Instrumentation knowledge and support exam preparation. Choose a topic below to get started.
1. |
Which of the following types of liquid chromatography uses immobilized biochemical as a stationary phase? |
A. | Ion exchange chromatography |
B. | Exclusion chromatography |
C. | Affinity chromatography |
D. | Gel permeation chromatography |
Answer» D. Gel permeation chromatography | |
2. |
Which of the following is not true about narrow bore column when compared to standard columns? |
A. | Internal diameter decreases |
B. | Volumetric flow decreases |
C. | Solvent cost is saved |
D. | Detector response time increases |
Answer» E. | |
3. |
Which of the following is not true about the radial compression column when compared to standard separation column? |
A. | Internal diameter decreases |
B. | Overall operating pressure decreases |
C. | Analysis time decreases |
D. | Solvent flow increases |
Answer» B. Overall operating pressure decreases | |
4. |
Which of the following is not true about the guard column used in liquid chromatography? |
A. | It filters particles that clog the separation column |
B. | It extends the lifetime of separation column |
C. | It allows particles that cause precipitation upon contact with stationary or mobile phase |
D. | The size of packing varies with the type of protection needed |
Answer» D. The size of packing varies with the type of protection needed | |
5. |
Which of the following will improve the efficiency of the separation process in liquid chromatography? |
A. | Increase in sample size, increase in column diameter |
B. | Reduction in sample size, increase in column diameter |
C. | Increase in sample size, reduction in column diameter |
D. | Reduction in sample size, reduction in column diameter |
Answer» E. | |
6. |
WHICH_OF_THE_FOLLOWING_IS_NOT_TRUE_ABOUT_NARROW_BORE_COLUMN_WHEN_COMPARED_TO_STANDARD_COLUMNS??$ |
A. | Internal diameter decreases |
B. | Volumetric flow decreases |
C. | Solvent cost is saved |
D. | Detector response time increases |
Answer» E. | |
7. |
Which of the following types of liquid chromatography uses immobilized biochemical as stationary phase?$ |
A. | Ion exchange chromatography |
B. | Exclusion chromatography |
C. | Affinity chromatography |
D. | Gel permeation chromatography |
Answer» D. Gel permeation chromatography | |
8. |
Which of the following is not true about radial compression column when compared to standard separation column? |
A. | Internal diameter decreases |
B. | Overall operating pressure decreases |
C. | Analysis time decreases |
D. | Solvent flow increases |
Answer» B. Overall operating pressure decreases | |
9. |
Which of the following is not a Column-type Liquid chromatography? |
A. | Gel permeation |
B. | Ion exchange |
C. | Liquid-solid |
D. | Paper |
Answer» E. | |
10. |
Which of the following columns are not used in liquid or high performance liquid chromatography? |
A. | Analytical column |
B. | Separation column |
C. | Guard column |
D. | Capillary column |
Answer» E. | |
11. |
Which of the following is not true about guard column used in liquid chromatography? |
A. | It filters particles that clog the separation column |
B. | It extends the lifetime of separation column |
C. | It allows particles that cause precipitation upon contact with stationary or mobile phase |
D. | The size of packing varies with the type of protection needed |
Answer» D. The size of packing varies with the type of protection needed | |
12. |
Which of the following are the practical problems that arise due to the decrease in column diameter? |
A. | Requirement of large particle size and high pressure drop |
B. | Requirement of large particle size and low pressure drop |
C. | Requirement of small particle size and high pressure drop |
D. | Requirement of small particle size and low pressure drop |
Answer» D. Requirement of small particle size and low pressure drop | |
13. |
Which of the following will improve the efficiency of separation process in liquid chromatography? |
A. | Increase in sample size, increase in column diameter |
B. | Reduction in sample size, increase in column diameter |
C. | Increase in sample size, reduction in column diameter |
D. | Reduction in sample size, reduction in column diameter |
Answer» E. | |
14. |
Which of the following is not a desired characteristic of pulse dampers or flow smootheners used in liquid chromatography? |
A. | Easy mobile phase change over |
B. | Constant flow must be maintained |
C. | Should be effective at low system pressure |
D. | Maximal dead volume |
Answer» E. | |
15. |
Which of the following is not a disadvantage of Pneumatic pumps used in liquid chromatography? |
A. | Pulsed output |
B. | Dependent on solvent viscosity |
C. | Dependent on back pressure |
D. | Inconvenient for solvent gradient elution |
Answer» B. Dependent on solvent viscosity | |
16. |
Which of the following is the disadvantage of reciprocating pump used in liquid chromatography? |
A. | Produces pulsed flow |
B. | Corrosive components |
C. | Does not have small hold-up value |
D. | Does not have moderate flow rate |
Answer» B. Corrosive components | |