Explore topic-wise MCQs in Analytical Instrumentation.

This section includes 16 Mcqs, each offering curated multiple-choice questions to sharpen your Analytical Instrumentation knowledge and support exam preparation. Choose a topic below to get started.

1.

Which of the following types of liquid chromatography uses immobilized biochemical as a stationary phase?

A. Ion exchange chromatography
B. Exclusion chromatography
C. Affinity chromatography
D. Gel permeation chromatography
Answer» D. Gel permeation chromatography
2.

Which of the following is not true about narrow bore column when compared to standard columns?

A. Internal diameter decreases
B. Volumetric flow decreases
C. Solvent cost is saved
D. Detector response time increases
Answer» E.
3.

Which of the following is not true about the radial compression column when compared to standard separation column?

A. Internal diameter decreases
B. Overall operating pressure decreases
C. Analysis time decreases
D. Solvent flow increases
Answer» B. Overall operating pressure decreases
4.

Which of the following is not true about the guard column used in liquid chromatography?

A. It filters particles that clog the separation column
B. It extends the lifetime of separation column
C. It allows particles that cause precipitation upon contact with stationary or mobile phase
D. The size of packing varies with the type of protection needed
Answer» D. The size of packing varies with the type of protection needed
5.

Which of the following will improve the efficiency of the separation process in liquid chromatography?

A. Increase in sample size, increase in column diameter
B. Reduction in sample size, increase in column diameter
C. Increase in sample size, reduction in column diameter
D. Reduction in sample size, reduction in column diameter
Answer» E.
6.

WHICH_OF_THE_FOLLOWING_IS_NOT_TRUE_ABOUT_NARROW_BORE_COLUMN_WHEN_COMPARED_TO_STANDARD_COLUMNS??$

A. Internal diameter decreases
B. Volumetric flow decreases
C. Solvent cost is saved
D. Detector response time increases
Answer» E.
7.

Which of the following types of liquid chromatography uses immobilized biochemical as stationary phase?$

A. Ion exchange chromatography
B. Exclusion chromatography
C. Affinity chromatography
D. Gel permeation chromatography
Answer» D. Gel permeation chromatography
8.

Which of the following is not true about radial compression column when compared to standard separation column?

A. Internal diameter decreases
B. Overall operating pressure decreases
C. Analysis time decreases
D. Solvent flow increases
Answer» B. Overall operating pressure decreases
9.

Which of the following is not a Column-type Liquid chromatography?

A. Gel permeation
B. Ion exchange
C. Liquid-solid
D. Paper
Answer» E.
10.

Which of the following columns are not used in liquid or high performance liquid chromatography?

A. Analytical column
B. Separation column
C. Guard column
D. Capillary column
Answer» E.
11.

Which of the following is not true about guard column used in liquid chromatography?

A. It filters particles that clog the separation column
B. It extends the lifetime of separation column
C. It allows particles that cause precipitation upon contact with stationary or mobile phase
D. The size of packing varies with the type of protection needed
Answer» D. The size of packing varies with the type of protection needed
12.

Which of the following are the practical problems that arise due to the decrease in column diameter?

A. Requirement of large particle size and high pressure drop
B. Requirement of large particle size and low pressure drop
C. Requirement of small particle size and high pressure drop
D. Requirement of small particle size and low pressure drop
Answer» D. Requirement of small particle size and low pressure drop
13.

Which of the following will improve the efficiency of separation process in liquid chromatography?

A. Increase in sample size, increase in column diameter
B. Reduction in sample size, increase in column diameter
C. Increase in sample size, reduction in column diameter
D. Reduction in sample size, reduction in column diameter
Answer» E.
14.

Which of the following is not a desired characteristic of pulse dampers or flow smootheners used in liquid chromatography?

A. Easy mobile phase change over
B. Constant flow must be maintained
C. Should be effective at low system pressure
D. Maximal dead volume
Answer» E.
15.

Which of the following is not a disadvantage of Pneumatic pumps used in liquid chromatography?

A. Pulsed output
B. Dependent on solvent viscosity
C. Dependent on back pressure
D. Inconvenient for solvent gradient elution
Answer» B. Dependent on solvent viscosity
16.

Which of the following is the disadvantage of reciprocating pump used in liquid chromatography?

A. Produces pulsed flow
B. Corrosive components
C. Does not have small hold-up value
D. Does not have moderate flow rate
Answer» B. Corrosive components