 
			 
			MCQOPTIONS
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				This section includes 16 Mcqs, each offering curated multiple-choice questions to sharpen your Analytical Instrumentation knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Which of the following types of liquid chromatography uses immobilized biochemical as a stationary phase? | 
| A. | Ion exchange chromatography | 
| B. | Exclusion chromatography | 
| C. | Affinity chromatography | 
| D. | Gel permeation chromatography | 
| Answer» D. Gel permeation chromatography | |
| 2. | Which of the following is not true about narrow bore column when compared to standard columns? | 
| A. | Internal diameter decreases | 
| B. | Volumetric flow decreases | 
| C. | Solvent cost is saved | 
| D. | Detector response time increases | 
| Answer» E. | |
| 3. | Which of the following is not true about the radial compression column when compared to standard separation column? | 
| A. | Internal diameter decreases | 
| B. | Overall operating pressure decreases | 
| C. | Analysis time decreases | 
| D. | Solvent flow increases | 
| Answer» B. Overall operating pressure decreases | |
| 4. | Which of the following is not true about the guard column used in liquid chromatography? | 
| A. | It filters particles that clog the separation column | 
| B. | It extends the lifetime of separation column | 
| C. | It allows particles that cause precipitation upon contact with stationary or mobile phase | 
| D. | The size of packing varies with the type of protection needed | 
| Answer» D. The size of packing varies with the type of protection needed | |
| 5. | Which of the following will improve the efficiency of the separation process in liquid chromatography? | 
| A. | Increase in sample size, increase in column diameter | 
| B. | Reduction in sample size, increase in column diameter | 
| C. | Increase in sample size, reduction in column diameter | 
| D. | Reduction in sample size, reduction in column diameter | 
| Answer» E. | |
| 6. | WHICH_OF_THE_FOLLOWING_IS_NOT_TRUE_ABOUT_NARROW_BORE_COLUMN_WHEN_COMPARED_TO_STANDARD_COLUMNS??$ | 
| A. | Internal diameter decreases | 
| B. | Volumetric flow decreases | 
| C. | Solvent cost is saved | 
| D. | Detector response time increases | 
| Answer» E. | |
| 7. | Which of the following types of liquid chromatography uses immobilized biochemical as stationary phase?$ | 
| A. | Ion exchange chromatography | 
| B. | Exclusion chromatography | 
| C. | Affinity chromatography | 
| D. | Gel permeation chromatography | 
| Answer» D. Gel permeation chromatography | |
| 8. | Which of the following is not true about radial compression column when compared to standard separation column? | 
| A. | Internal diameter decreases | 
| B. | Overall operating pressure decreases | 
| C. | Analysis time decreases | 
| D. | Solvent flow increases | 
| Answer» B. Overall operating pressure decreases | |
| 9. | Which of the following is not a Column-type Liquid chromatography? | 
| A. | Gel permeation | 
| B. | Ion exchange | 
| C. | Liquid-solid | 
| D. | Paper | 
| Answer» E. | |
| 10. | Which of the following columns are not used in liquid or high performance liquid chromatography? | 
| A. | Analytical column | 
| B. | Separation column | 
| C. | Guard column | 
| D. | Capillary column | 
| Answer» E. | |
| 11. | Which of the following is not true about guard column used in liquid chromatography? | 
| A. | It filters particles that clog the separation column | 
| B. | It extends the lifetime of separation column | 
| C. | It allows particles that cause precipitation upon contact with stationary or mobile phase | 
| D. | The size of packing varies with the type of protection needed | 
| Answer» D. The size of packing varies with the type of protection needed | |
| 12. | Which of the following are the practical problems that arise due to the decrease in column diameter? | 
| A. | Requirement of large particle size and high pressure drop | 
| B. | Requirement of large particle size and low pressure drop | 
| C. | Requirement of small particle size and high pressure drop | 
| D. | Requirement of small particle size and low pressure drop | 
| Answer» D. Requirement of small particle size and low pressure drop | |
| 13. | Which of the following will improve the efficiency of separation process in liquid chromatography? | 
| A. | Increase in sample size, increase in column diameter | 
| B. | Reduction in sample size, increase in column diameter | 
| C. | Increase in sample size, reduction in column diameter | 
| D. | Reduction in sample size, reduction in column diameter | 
| Answer» E. | |
| 14. | Which of the following is not a desired characteristic of pulse dampers or flow smootheners used in liquid chromatography? | 
| A. | Easy mobile phase change over | 
| B. | Constant flow must be maintained | 
| C. | Should be effective at low system pressure | 
| D. | Maximal dead volume | 
| Answer» E. | |
| 15. | Which of the following is not a disadvantage of Pneumatic pumps used in liquid chromatography? | 
| A. | Pulsed output | 
| B. | Dependent on solvent viscosity | 
| C. | Dependent on back pressure | 
| D. | Inconvenient for solvent gradient elution | 
| Answer» B. Dependent on solvent viscosity | |
| 16. | Which of the following is the disadvantage of reciprocating pump used in liquid chromatography? | 
| A. | Produces pulsed flow | 
| B. | Corrosive components | 
| C. | Does not have small hold-up value | 
| D. | Does not have moderate flow rate | 
| Answer» B. Corrosive components | |