MCQOPTIONS
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MCQOPTIONS
This section includes 94 Mcqs, each offering curated multiple-choice questions to sharpen your Cell Biology knowledge and support exam preparation. Choose a topic below to get started.
| 51. |
Cancer cells depend on _________________ metabolic pathway. |
| A. | Effectors |
| B. | Primary messengers |
| C. | Secondary messengers |
| D. | G-proteins |
| Answer» E. | |
| 52. |
Endostatin is a ___________________ |
| A. | angiogenesis inhibitor |
| B. | angiogenesis promoter |
| C. | transcription factor |
| D. | cell surface receptor |
| Answer» B. angiogenesis promoter | |
| 53. |
Which agents are used in passive immunotherapy of cancer? |
| A. | Antigens |
| B. | Antibodies |
| C. | Anticoaggulants |
| D. | Antacids |
| Answer» C. Anticoaggulants | |
| 54. |
B-lymphocytes that do not differentiate into plasma cells are called _______________________ |
| A. | T-lymphocytes |
| B. | Helper T-cells |
| C. | Memory B cells |
| D. | Memory T-cells |
| Answer» D. Memory T-cells | |
| 55. |
Which of the following drug acts by stimulating toll-like receptors (TLRs)? |
| A. | Doxorubicin |
| B. | Neosporin |
| C. | Aldara |
| D. | Vimentin |
| Answer» D. Vimentin | |
| 56. |
T-cells are activated by _______________ |
| A. | autoantibodies |
| B. | antibodies |
| C. | fragments of antigens |
| D. | intact antigens |
| Answer» D. intact antigens | |
| 57. |
For the development of cancer, which of the following is the most influential component of the genome? |
| A. | EGF |
| B. | Cytochrome c |
| C. | TP53 |
| D. | T53 |
| Answer» D. T53 | |
| 58. |
Which of the following proteins in fruit fly play the major function of dorsoventral polarity of the fly embryo? |
| A. | Toll |
| B. | NEF1 |
| C. | Transposons |
| D. | Linker DNA |
| Answer» B. NEF1 | |
| 59. |
Cytokines are ________________ |
| A. | antigens |
| B. | proteins |
| C. | polysaccharides |
| D. | carbohydrates |
| Answer» C. polysaccharides | |
| 60. |
According to the “instructive model” the antigen instructs lymphocytes to produce antibodies. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 61. |
Plasma cells are mainly found in the bone marrow. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 62. |
Which of the following group of pathogens always reside intracellularly in the host? |
| A. | virus |
| B. | fungi |
| C. | molds |
| D. | bacteria |
| Answer» B. fungi | |
| 63. |
The activation of T-cell by the dendritic cells is associated with __________________ |
| A. | increase in magnesium ions |
| B. | decrease in magnesium ions |
| C. | increase in calcium ions |
| D. | decrease in calcium ions |
| Answer» D. decrease in calcium ions | |
| 64. |
Which of the following is the main target of HIV? |
| A. | Helper T cells |
| B. | Autoantibodies |
| C. | Cytotoxic T cells |
| D. | B lymphocytes |
| Answer» B. Autoantibodies | |
| 65. |
What is not required in the innate immune responses? |
| A. | antigen |
| B. | strong immunity |
| C. | pathogen |
| D. | previous contact |
| Answer» E. | |
| 66. |
The dendritic cells were discovered by _______________ |
| A. | Ralph Steinman |
| B. | Barry Marshall |
| C. | David Baltimore |
| D. | Peter Medawar |
| Answer» B. Barry Marshall | |
| 67. |
Which of the following is not a DNA tumor virus? |
| A. | SV40 |
| B. | HIV |
| C. | Adenovirus |
| D. | Polyoma virus |
| Answer» C. Adenovirus | |
| 68. |
Adaptive immune responses are more specific that innate immune responses. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 69. |
When was it discovered that there is a correlation between cancer and the environment? |
| A. | 1675 |
| B. | 1775 |
| C. | 1875 |
| D. | 1975 |
| Answer» C. 1875 | |
| 70. |
Helper T lymphocytes possess ____________ proteins on their surface. |
| A. | CD2 |
| B. | CD3 |
| C. | CD4 |
| D. | CD5 |
| Answer» D. CD5 | |
| 71. |
Which of the following is an antimicrobial peptide synthesized by lymphocytes? |
| A. | adhesins |
| B. | condensins |
| C. | defensins |
| D. | complement |
| Answer» D. complement | |
| 72. |
Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the risk of __________________ |
| A. | Colon cancer |
| B. | Breast cancer |
| C. | HIV |
| D. | Herpes |
| Answer» B. Breast cancer | |
| 73. |
Antigens that do not require the involvement of T-cells for the activation of B-cells are _____________________ |
| A. | thymus-dependent |
| B. | thymus-independent |
| C. | intracellular pathogens |
| D. | facultative anaerobes |
| Answer» C. intracellular pathogens | |
| 74. |
Some of the activated B-cells lead to the formation of short-lived ______________________ |
| A. | plasma cells |
| B. | evanescent waves |
| C. | memory cells |
| D. | thymus cells |
| Answer» B. evanescent waves | |
| 75. |
In which year was the two “gene – one polypeptide” hypothesis put forward? |
| A. | 1945 |
| B. | 1955 |
| C. | 1965 |
| D. | 1975 |
| Answer» D. 1975 | |
| 76. |
Which of the following virus is associated with Kaposi’s sarcoma? |
| A. | Herpes-virus |
| B. | Hepatitis virus |
| C. | HIV |
| D. | Epstein-Barr virus |
| Answer» B. Hepatitis virus | |
| 77. |
Which drug was approved in 1997 for the treatment of non-Hodgkin’s B-cell lymphoma? |
| A. | Neosporin |
| B. | Rituxan |
| C. | Vectibix |
| D. | Arzerra |
| Answer» C. Vectibix | |
| 78. |
The antigenic determinant is called _________________ |
| A. | epitope |
| B. | epitome |
| C. | microbiome |
| D. | metagenome |
| Answer» B. epitome | |
| 79. |
Proto-oncogenes are possessed by the ______________________ |
| A. | RNA virus |
| B. | DNA virus |
| C. | Cells themselves |
| D. | Pathogenic bacteria |
| Answer» D. Pathogenic bacteria | |
| 80. |
Which of the following serves as antigen receptors? |
| A. | antibodies |
| B. | cytokines |
| C. | chemokines |
| D. | necrosis factors |
| Answer» B. cytokines | |
| 81. |
A harmless version of tetanus toxin is called _________________ |
| A. | clostridium |
| B. | plasmid |
| C. | toxoid |
| D. | thylakoid |
| Answer» D. thylakoid | |
| 82. |
A rare disease congenital agammaglobulinemia is caused due to abnormality in __________________ |
| A. | humoral antibody |
| B. | cell-mediated immunity |
| C. | acidic/alkaline pH |
| D. | homeostasis |
| Answer» B. cell-mediated immunity | |
| 83. |
After the clearance of foreign antigen, the expanded T-cell population ________________ |
| A. | dies by apoptosis |
| B. | increases in size |
| C. | remains in the circulatory system |
| D. | remains in lymph nodes |
| Answer» B. increases in size | |
| 84. |
Proliferation of T-cells in response to antigen presentation is accompanied by enlargement of __________________ |
| A. | lymph nodes |
| B. | area of infection |
| C. | size of antibody |
| D. | size of B-cells |
| Answer» B. area of infection | |
| 85. |
B and T lymphocytes arise from _____________ |
| A. | hematopoietic stem cells |
| B. | germ cells |
| C. | somatic cells |
| D. | spermatocytes |
| Answer» B. germ cells | |
| 86. |
Which segment of chromosome 2 encodes for the V region of antibody? |
| A. | A segment |
| B. | C segment |
| C. | V-segment |
| D. | J-segment |
| Answer» E. | |
| 87. |
Cyclosporin A is a drug that __________________ |
| A. | suppresses the immune system |
| B. | increases body temperature |
| C. | increases the production of antibodies |
| D. | decreases body temperature |
| Answer» B. increases body temperature | |
| 88. |
Fragments of antigens are held at the surface of antigen presenting cells by _________________ |
| A. | histones |
| B. | antibodies |
| C. | major histocompatibility complex |
| D. | epitope |
| Answer» D. epitope | |
| 89. |
Class-switching of antibodies can occur by changing the ___________________ |
| A. | heavy chain |
| B. | light chain |
| C. | pH |
| D. | temperature |
| Answer» B. light chain | |
| 90. |
When cancer cells are grown in culture they do not form monolayers. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 91. |
The two important compounds of serum that are necessary for cell culture are __________________ |
| A. | insulin, epidermal growth factor |
| B. | insulin, phosphatidylserine |
| C. | tumor necrosis factor, epidermal growth factor |
| D. | epidermal growth factor, phosphatidylserine |
| Answer» B. insulin, phosphatidylserine | |
| 92. |
The normal cells tend to remain in monolayer when their _____________ decreases. |
| A. | pH |
| B. | volume |
| C. | genomic content |
| D. | growth rate |
| Answer» E. | |
| 93. |
Normal cells can be converted to cancer cells by treatment with _____________ |
| A. | carcinogenic compounds |
| B. | endonucleases |
| C. | exonucleases |
| D. | kinases |
| Answer» B. endonucleases | |
| 94. |
Cancer is an inherited disease. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |