MCQOPTIONS
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MCQOPTIONS
This section includes 18 Mcqs, each offering curated multiple-choice questions to sharpen your Genetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Determine the correctness or otherwise of the following Asertion (a) and the Reason (r) Assertion : MTT assay is used to determine cell viability based on the principle of colour formation by DNA fragmentation. Reason : MTT assay is used to determine cell viability based on the colour development by converting tetrazolium soluble salt to insoluble salt. |
| A. | both (a) and (r) are true and (r) is the correct reason for (a) |
| B. | both (a) and (r) are true and (r) is not the correct reason for (a) |
| C. | (a) is true but (r) is false |
| D. | (a) is false but (r) is true |
| Answer» E. | |
| 2. |
Which of the following characteristics with respect to bacterial DNA polymerase III are TRUE? P. Initiation of chain synthesisQ. 5 3 polymerization R. 3 5 exonuclease activity S. 5 3 exonuclease activity |
| A. | P and Q only |
| B. | Q and R only |
| C. | Q and S only |
| D. | P and S only |
| Answer» C. Q and S only | |
| 3. |
Determine the correctness or otherwise of the following Assertion (A) and the Reason (R). Assertion : Isopropylthiogalactoside (IPTG) is a gratuitous inducer of lactose operon. Reason : Gratuitous inducers are chemical analogs which behave like natural inducer but they do not serve as substrate for the enzymes that are subsequently synthesized. |
| A. | both (A) and (R) are true and (R) is the correct reason for (A) |
| B. | both (A) and (R) are true but (R) is not the correct reason for (A) |
| C. | (A) is true but (R) is false |
| D. | (A) is false but (R) is true |
| Answer» B. both (A) and (R) are true but (R) is not the correct reason for (A) | |
| 4. |
Mobile genetic elements present in human genome are P. long interspersed elements (LINEs)Q. short interspersed elements (SINEs)R. P elementsS. IS elements |
| A. | Q, R |
| B. | P, Q |
| C. | P, R |
| D. | Q, S |
| Answer» C. P, R | |
| 5. |
Presence of CX2 4 CX X8HX3H sequence in a protein suggest that it is |
| A. | a protein kinase |
| B. | GTP binding protein |
| C. | zinc finger protein |
| D. | lipase |
| Answer» D. lipase | |
| 6. |
Determine the correctness or otherwise of the following Assertion (a) and Reason (r):Assertion (a): IPTG (Isopropylthiogalactoside) is a gratuitous inducer of lac operon. Reason (r) : IPTG is an efficient inducer, but not a substrate of lac operon |
| A. | Both (a) and (r) are true and (r) is the correct reason for (a) |
| B. | Both (a) and (r) are true but (r) is not the correct reason for (a) |
| C. | (a) is true but (r) is false |
| D. | (a) is false but (r) is true |
| Answer» C. (a) is true but (r) is false | |
| 7. |
Which of the following are commonly used as reporter genes? P. NPTgene Q. Luciferase gene R. CFTR gene S. GFPgene |
| A. | Q, S |
| B. | R,S |
| C. | P, R |
| D. | P, Q |
| Answer» B. R,S | |
| 8. |
Match the following antibiotics in Group I with their mode of action in Group IIGroup IGroup IIP. Chloramphenicol1. 0Binds to DNA gyrase1Q. Norfloxacin2. Binds to RNAPolymeraseR. Puromycin3. Inhibits peptidyltransferaseS. Rifampicin4. Mimics aminoacyl tRNA |
| A. | P-1, Q-3, R-2, S-4 |
| B. | P-3, Q-1, R-2, S-4 |
| C. | P-3, Q-1, R-4, S-2 |
| D. | P-4, Q-2, R-3, S-1 |
| Answer» D. P-4, Q-2, R-3, S-1 | |
| 9. |
Determine the correctness of the following statements I. Enhancer sequences are those DNA sequences that are involved in increasing the rate of DNA replication. II. Enhancer sequences work by binding with eukaryotic gene activator factors. |
| A. | only I is true |
| B. | only II is true |
| C. | both I and II are true |
| D. | both I and II are false |
| Answer» C. both I and II are true | |
| 10. |
The enzymes that can be used in 5 end labeling of DNA are(P) alkaline phosphatase(Q) DNA ligase(R) terminal transferase(S) polynucleotide kinase |
| A. | P, S |
| B. | R, Q |
| C. | P, R |
| D. | R, S |
| Answer» B. R, Q | |
| 11. |
Determine the correctness or otherwise of the following Assertion (A) and the Reason (R). Assertion : N-methyl-N -nitro-N-nitrosoguanidine (NTG) is an effective chemical mutagen. Reason : Mutations induced by NTG mainly are the GC AT transitions. |
| A. | both (A) and (R) are true and (R) is the correct reason for (A) |
| B. | both (A) and (R) are true but (R) is not the correct reason for (A) |
| C. | (A) is true but (R) is false |
| D. | (A) is false but (R) is true |
| Answer» B. both (A) and (R) are true but (R) is not the correct reason for (A) | |
| 12. |
The total number of fragments generated by the complete and sequential cleavage of the polypeptide given below by Trypsin followed by CNBr is _______ Phe-Trp-Met-Gly-Ala-Lys-Leu-Pro-Met-Asp-Gly-Arg-Cys-Ala-Gln |
| A. | 1 |
| B. | 3 |
| C. | 5 |
| D. | 7 |
| Answer» D. 7 | |
| 13. |
Match the entries in Group Iwith the entries in Group II.Group IGroup IIP. RNAse P1. PolyadenylationQ. RNase H2. SplicingR. snRNAs3. RibozymesS. CstF4. DNA-RNAhybrids |
| A. | P-3, Q-4, R-2, S-1 |
| B. | P-4, Q-3, R-2, S-1 |
| C. | P-3, Q-2, R-1, S-4 |
| D. | P-2, Q-4, R-1, S-3 |
| Answer» B. P-4, Q-3, R-2, S-1 | |
| 14. |
Match the drugs in Group I with their mechanism of action in Group II. Group I P. PaclitaxelQ. Colchicine R. Etoposide S. Methotrexate Group II1. Inhibits protein translation 2. Inhibits microtubule depolymerization3. Inhibits DNA replication 4. Alkylates DNA 5. Inhibits dihydrofolate reductase 6. Inhibits microtubule polymerization |
| A. | P-1, Q-6, R-3, S-4 |
| B. | P-2, Q-6, R-3, S-5 |
| C. | P-1, Q-3, R-6, S-5 |
| D. | P-2, Q-3, R-6, S-4 |
| Answer» C. P-1, Q-3, R-6, S-5 | |
| 15. |
The percentage SIMILARITIES and IDENTITIES, respectively, between the two peptide sequences given below will be ______% and _____%. Peptide I : Ala-Ala-Arg-Arg-Gln-Trp-Leu-Thr-Phe-Thr-Lys-Ile-Met-Ser-GluPeptide II: Ala-Ala-Arg-Glu-Gln-Tyr-Ile-Ser-Phe-Thr-Lys-Ile-Met-Arg-Asp |
| A. | 80, 80 |
| B. | 80, 60 |
| C. | 60, 60 |
| D. | 90, 60 |
| Answer» C. 60, 60 | |
| 16. |
A DNA sequence, 5 -A T G G A C G T G C T T C C C A A A G C A T C G G G C 3 , is mutated to obtain P. 5 -A T G G A C G T G C T T C a C A A A G C A T C G G G C 3 Q. 5 -A T G G A C G T G C T T C C C g A A A G C A T C G G G C 3 R. 5 -A T G G A C G T G C T T C C A A A G C A T C G G G C 3 S. 5 -A T G G A C G T G C T T C C C A A t G C A T C G G G C 3 T. 5 -A T G G A C G a G C T T C C C A A A G C A T C G G G C 3 [Point mutations are shown in the lower case or within the sequences] Which of the above mutant sequences DO NOT have frame-shift? |
| A. | P, Q and S |
| B. | P, S and T |
| C. | Q, R and S |
| D. | Q, S and T |
| Answer» C. Q, R and S | |
| 17. |
Which set of the following events occurs during the elongation step of translation? P. Attachment of mRNA with the smaller subunit of ribosome Q. Loading of correct aminoacyl-tRNA into the A site R. Formation of a peptide bond between the aminoacyl-tRNA in the A site and the peptide chain that is attached to the peptidyl-tRNA in the P site S. Dissociation of the ribosomal subunits T. Translocation of peptidyl-tRNA from the A site to the P site of the ribosome |
| A. | P, Q and R |
| B. | P, Q and T |
| C. | Q, R and T |
| D. | R, S and T |
| Answer» D. R, S and T | |
| 18. |
An in vitor translation system can synthesize peptides in all three reading frames of the RNA template. When 5 -UCUCUCUC---(UC)n--- UCUCUCUC - 3 was used as the template in this in vitro translation system, the synthesized peptides contained 50% each of serine and leucine. When 5 -CCUCCUCCU---(CCU)n---CCUCCU-3 was used as the template, the synthesized peptides contained 33.3% each of serine, leucine, and proline. Deduce the condon for proline. |
| A. | UCU |
| B. | CUC |
| C. | CCU |
| D. | UCC |
| Answer» D. UCC | |