MCQOPTIONS
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MCQOPTIONS
This section includes 8 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
To your cultured cell lines, you add growth factors like cytokines which act through MAPK cascade pathway. Which transition will it trigger? |
| A. | S->G2 |
| B. | M->Anaphase |
| C. | G1->S |
| D. | G2->M |
| Answer» D. G2->M | |
| 2. |
In an experiment, you are working on mitochondrial chromosomes. Which polymerase will ensure accurate replication? |
| A. | pol beta |
| B. | pol delta |
| C. | pol iota |
| D. | pol gamma |
| Answer» E. | |
| 3. |
What is the DNA composition of ARS? |
| A. | A-T rich |
| B. | G-C rich |
| C. | Repeating A-T, G-C sequence |
| D. | No specific sequence speciality |
| Answer» B. G-C rich | |
| 4. |
Which Cyclin-CDK complex will you find most active in M phase? |
| A. | Cyclin A- CDK 2 |
| B. | Cyclin B- CDK 1 |
| C. | Cyclin D- CDK 2 |
| D. | Cyclin E- CDK 1 |
| Answer» C. Cyclin D- CDK 2 | |
| 5. |
Pre-replication complex is necessary to initiate replication. It assembles in______________ |
| A. | Late Anaphase |
| B. | G1 phase |
| C. | S phase |
| D. | Early Anaphase |
| Answer» C. S phase | |
| 6. |
What is the fate of phosphorylated Cdc 6? |
| A. | It is transported outside nucleus |
| B. | It is ubiquitinylated |
| C. | It gets activated |
| D. | It forms a complex with Cdt |
| Answer» C. It gets activated | |
| 7. |
Which of these would you use as a competitive inhibitor for Cdt? |
| A. | MCM 1 |
| B. | MCM 2 |
| C. | MCM 7 |
| D. | MCM 10 |
| Answer» E. | |
| 8. |
Cyclin-CDK complex (here considering S cyclin) when active is responsible for phosphorylating several proteins and this often marks then for destruction by ubiquitination. What would be its effect on Cdt activity? |
| A. | Activation |
| B. | Inactivation |
| C. | Destruction |
| D. | Increased synthesis |
| Answer» B. Inactivation | |