MCQOPTIONS
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MCQOPTIONS
This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Cell size is regulated by_____________ |
| A. | Hct1 |
| B. | Cdc6 |
| C. | MDM2 |
| D. | Cln 3 |
| Answer» E. | |
| 2. |
Which of the following Cdk is resistant to Hct1? |
| A. | G1 |
| B. | G1-S |
| C. | Both G1 and G1-S |
| D. | G1, G1 S and S |
| Answer» D. G1, G1 S and S | |
| 3. |
M cyclin cdk is activated by positive feedback loop. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 4. |
Sic1 can bind and inhibit ___________ Cdk and it is inhibited by ________ cdk. |
| A. | G1, M |
| B. | M, M |
| C. | S, S |
| D. | M, S |
| Answer» C. S, S | |
| 5. |
In the G1 phase which of the following has a high level? |
| A. | Hct1 |
| B. | CDC20 |
| C. | M cyclin CDk |
| D. | S cyclin |
| Answer» B. CDC20 | |
| 6. |
M cyclin CDK _________________ cdc20 and ______________ Hct1? |
| A. | Activates, activates |
| B. | Activates, inactivates |
| C. | Inactivates, activates |
| D. | Inactivates, activates |
| Answer» C. Inactivates, activates | |
| 7. |
Which Cdc is responsible for the destruction of M cyclin – Cdk complex? |
| A. | Cdc6 |
| B. | Cdc20 |
| C. | Cdc30 |
| D. | Cdc42 |
| Answer» C. Cdc30 | |
| 8. |
Which CDK is responsible for nuclear membrane disintegration? |
| A. | G1 |
| B. | S |
| C. | M |
| D. | A |
| Answer» D. A | |
| 9. |
What is the fate of cdc6 after origin firing? |
| A. | It is sequestered by geminin |
| B. | It is phosphorylated and thus can no longer interact |
| C. | It is irreversibly bound to ORC |
| D. | It is phosphorylated, ubiquitin is added and destroyed |
| Answer» E. | |
| 10. |
Which CDK triggers origin firing? |
| A. | G1 |
| B. | G1-S |
| C. | S |
| D. | M |
| Answer» D. M | |
| 11. |
Which of the following acts as a licensing factor for replication? |
| A. | ORC |
| B. | Cdt |
| C. | MCM |
| D. | CDC42 |
| Answer» D. CDC42 | |
| 12. |
Which one of the following acts as CKI? |
| A. | P20 |
| B. | p27 |
| C. | p35 |
| D. | p53 |
| Answer» C. p35 | |
| 13. |
Which of the following ubiquitin ligase concentration is regulated for proper cell cycle progression? |
| A. | E1 |
| B. | E2 |
| C. | E3 |
| D. | E4 |
| Answer» D. E4 | |
| 14. |
Which is the irreversible stage for progression of cell division? |
| A. | G1 |
| B. | S |
| C. | G2 |
| D. | M |
| Answer» C. G2 | |
| 15. |
Check points in the cell cycle are dependent on __________________ |
| A. | Time dependent regulation |
| B. | Volume dependent regulation |
| C. | Positive feedback regulation |
| D. | Negative feedback regulation |
| Answer» E. | |