MCQOPTIONS
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MCQOPTIONS
This section includes 50 Mcqs, each offering curated multiple-choice questions to sharpen your VITEEE knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The mutagenicity of a compound can be detected by- |
| A. | ELISA |
| B. | Ame’s test |
| C. | Western blotting |
| D. | Any of the above. |
| Answer» C. Western blotting | |
| 2. |
The binding of the prokaryotic DNA dependent RNA polymerase to promoter site is inhibited by- |
| A. | Streptomycin |
| B. | Puromycin |
| C. | Rifampicin |
| D. | Tetracycline |
| Answer» D. Tetracycline | |
| 3. |
What is added to the 3′-end of many eukaryotic mRNAs after transcription? |
| A. | Introns |
| B. | Cap of modified G nucleotide |
| C. | Poly A tail |
| D. | Trinucleotide CCA |
| Answer» D. Trinucleotide CCA | |
| 4. |
The p53 protein normally promotes |
| A. | DNA replication |
| B. | Cell division |
| C. | Tumor formation |
| D. | Apoptosis |
| Answer» E. | |
| 5. |
BRCA-1 is associated with which cancer? |
| A. | Breast |
| B. | Nerve |
| C. | Thyroid |
| D. | Leukemia |
| Answer» B. Nerve | |
| 6. |
Which of the following events would occur at the E. coli lac operon when the glucose concentration of the growth medium is low and the lactose concentration is high? |
| A. | The lac repressor protein will bind to the operator sequence. |
| B. | Ribosomes will stall during translation of the first 13 amino acids. |
| C. | The transcribed RNA will form a cAMP-dependent stem-loop structure to terminate transcription. |
| D. | The catabolite gene activator protein (CAP), bound with cAMP, will stimulate binding of RNA polymerase to the promoter. |
| Answer» E. | |
| 7. |
A 10-year-old Caucasian girl is brought in by her parents for evaluation of a skin disorder. The child has many freckles on her face, arms, and legs. The parents were told by previous physicians that she suffers from Xeroderma pigmentosum and that they should limit her exposure to sun light. What is the most likely etiology of this disorder? |
| A. | Deficient DNA replication |
| B. | Impaired DNA repair by nucleotide excision |
| C. | Defective RNA transcription from TATA-less promoter |
| D. | Impaired DNA repair by photo reactivation |
| Answer» C. Defective RNA transcription from TATA-less promoter | |
| 8. |
Which of the following is an anticancer drug? |
| A. | methyl thymidine |
| B. | Ribose phosphate |
| C. | Ara C |
| D. | PRPP (5- phosphoribosylpyrophosphate) |
| Answer» D. PRPP (5- phosphoribosylpyrophosphate) | |
| 9. |
Which of the following result is provided by Western Blot Analysis |
| A. | Detects DNA molecules |
| B. | Detects Protein molecules |
| C. | Detects RNA molecules |
| D. | Determines chromosomal structure |
| Answer» C. Detects RNA molecules | |
| 10. |
All are true for DNA polymerase except one- |
| A. | Has exonuclease activity |
| B. | Works only in 5`to 3` direction |
| C. | Edits as it synthesizes |
| D. | Synthesizes RNA primer to initiate DNA synthesis. |
| Answer» E. | |
| 11. |
A promoter site on DNA – |
| A. | is present upstream to the start site |
| B. | is present on the coding strand |
| C. | Initiates transcription |
| D. | All of the above |
| Answer» E. | |
| 12. |
In protein synthesis which out of the following is not a termination codon? |
| A. | UAG |
| B. | UGA |
| C. | UUU |
| D. | UAA |
| Answer» D. UAA | |
| 13. |
Actinomycin D is an inhibitor of- |
| A. | Replication |
| B. | Transcription |
| C. | Translation |
| D. | all of the above |
| Answer» C. Translation | |
| 14. |
The melting temperature of DNA is the temperature where: |
| A. | DNA anneals to RNA |
| B. | DNA denatures into single strands |
| C. | DNA is degraded |
| D. | RNA binds to the ribosome |
| Answer» C. DNA is degraded | |
| 15. |
Eukaryotic RNA polymerase I is specialized to transcribe which of the following? |
| A. | mRNA |
| B. | tRNA |
| C. | Ribosomal RNA |
| D. | Mitochondrial RNA |
| Answer» D. Mitochondrial RNA | |
| 16. |
- Telomerase does which of the following- |
| A. | Joins Okazaki fragments on the lagging strand |
| B. | Catalyzes DNA replication at the ends of chromosome |
| C. | Enhances transcription |
| D. | Requires dCTP |
| Answer» C. Enhances transcription | |
| 17. |
DNA is replicated: |
| A. | Conservatively |
| B. | Distributively |
| C. | Semi-conservatively |
| D. | Dispersively |
| Answer» D. Dispersively | |
| 18. |
In contrast to DNA polymerase, RNA polymerase |
| A. | Fills in the gap between Okazaki fragments |
| B. | Works only in 5`to 3` direction |
| C. | Edits as it synthesizes |
| D. | Synthesizes RNA primer to initiate DNA synthesis. |
| Answer» E. | |
| 19. |
Enhancer regions in eukaryotic DNA are – |
| A. | DNA Pol I binding sites |
| B. | Inhibit the binding of repressor |
| C. | Enhance the frequency of transcription |
| D. | Specific for given set of genes |
| Answer» D. Specific for given set of genes | |
| 20. |
The part of the bacterial RNA polymerase responsible for recognizing the promoter is the: |
| A. | Alpha subunit |
| B. | Rho protein |
| C. | DNA Pol III |
| D. | sigma subunit |
| Answer» E. | |
| 21. |
Which of the following is false about the E. coli Lac operon? |
| A. | It is polycistronic |
| B. | It is an example of negative control |
| C. | The presence of lactose acts as an inducer |
| D. | The repressor binds to the promoter |
| Answer» E. | |
| 22. |
Which of the following is not a cloning vector? |
| A. | Helicase |
| B. | PBR322 |
| C. | SV40 |
| D. | E.coli genomic DNA |
| Answer» B. PBR322 | |
| 23. |
Histones have an abundance of which of the following amino acids? |
| A. | Lysine and arginine |
| B. | Alanine and glutamine |
| C. | Glycine and Glutamine |
| D. | Arginine and Glutamine |
| Answer» B. Alanine and glutamine | |
| 24. |
-The RNA primer is removed from the Okazaki fragment by: |
| A. | DNA Pol I |
| B. | DNA Pol II |
| C. | DNA Pol III |
| D. | RNA polymerase |
| Answer» B. DNA Pol II | |
| 25. |
Which of the following m RNA s lack poly A tail? |
| A. | Ferritin |
| B. | Interferon |
| C. | Insulin |
| D. | None of the above. |
| Answer» C. Insulin | |
| 26. |
Nucleosomes |
| A. | Bind to RNA pol II |
| B. | Package prokaryotic DNA |
| C. | Are only present in prokaryotes |
| D. | Are composed on an octamer of histones and ~150 bp of DNA |
| Answer» E. | |
| 27. |
Which of the following enzyme(s) can remove or insert supercoil twists into circular DNA? |
| A. | Topoisomerases |
| B. | DNA Pol II |
| C. | Spliceosomes |
| D. | Helicase |
| Answer» B. DNA Pol II | |
| 28. |
Repressor molecules bind to the: |
| A. | Promoter |
| B. | Enhancer |
| C. | Operator |
| D. | Hormone response element |
| Answer» D. Hormone response element | |
| 29. |
The only nucleoside with base to sugar C-C linkage is- |
| A. | Thymidine |
| B. | Pseudouridine |
| C. | Cytidine |
| D. | Adenosine |
| Answer» C. Cytidine | |
| 30. |
The only methylated base in mammals is? |
| A. | -methyl guanine |
| B. | Thymine |
| C. | Methyl adenine |
| D. | 5-methyl cytosine |
| Answer» C. Methyl adenine | |
| 31. |
Which of the followings is required for end to end joining of DNA |
| A. | DNA Pol I |
| B. | DNA ligase |
| C. | DNA Pol III |
| D. | RNA polymerase |
| Answer» C. DNA Pol III | |
| 32. |
How many hydrogen bonds form between U and A in a Watson-Crick base pair interactions? |
| A. | 0 |
| B. | 1 |
| C. | 2 |
| D. | 3 |
| Answer» D. 3 | |
| 33. |
-Which of the followings does NOT need a primer in order to function? |
| A. | DNA Pol I |
| B. | DNA Pol II |
| C. | DNA Pol III |
| D. | RNA polymerase |
| Answer» E. | |
| 34. |
Which of the following process utilizes proofreading to increase its accuracy? |
| A. | transcription |
| B. | DNA replication |
| C. | recombination |
| D. | electron transport |
| Answer» C. recombination | |
| 35. |
Which of the following statements regarding photosynthesis is not true? |
| A. | The light cycle occurs only during exposure to light. |
| B. | Red and blue are optimal for photosynthetic function |
| C. | ATP is produced during the light cycle. |
| D. | The dark cycle occurs only in the absence of light. |
| Answer» E. | |
| 36. |
Cells that involved in active transport such as cells of the intestinal epithelium, utilize large quantities of ATP. In such cells, there are |
| A. | many polyribosomes |
| B. | many mitochondria |
| C. | many lysosomes |
| D. | high level of adenylate cyclise activity |
| Answer» C. many lysosomes | |
| 37. |
Which of the following statements about viruses is not true? |
| A. | The protein coat of the virus does not enter a host bacterial cell |
| B. | Their genetic material may be DNA or DNA |
| C. | The virus may replicate in a bacterial host |
| D. | The virus may replicate autonomously in the absence of a host |
| Answer» E. | |
| 38. |
Which of the flowing is a correct association? |
| A. | Polysome: group of Golgi complexes |
| B. | Ribosome: electron transport chain |
| C. | Lysosome: digestive enzyme for intracellular use |
| D. | Mitochondria: transport materials from the nucleus to the cytoplasm |
| Answer» D. Mitochondria: transport materials from the nucleus to the cytoplasm | |
| 39. |
Which of the following statements about the Krebs cycle is not true? |
| A. | The Krebs cycle is linked to glycolysis by pyruvate |
| B. | The Krebs cycle produces nucleotides such as NADH and FADH2 |
| C. | Citrate is an intermediate in the Krebs cycle |
| D. | The Krebs cycle is the single greatest source of ATP in the cell |
| Answer» E. | |
| 40. |
The tRNA anticodon for the amino acid valine is CAA(reading 3’ to 5’). What is the mRNA codon for valine (reading 5’ to 3’) |
| A. | TTG |
| B. | True GGU |
| C. | CCA |
| D. | UGG |
| Answer» C. CCA | |
| 41. |
Which is not a characteristic of proteins? |
| A. | waxes |
| B. | albumins |
| C. | carotenoids |
| D. | Lecithin |
| Answer» C. carotenoids | |
| 42. |
What is the Best evidence that genes encode the amino acid sequence of proteins? |
| A. | proteins are macromolecules |
| B. | The amino acid sequence of polypeptide is changed by gene mutation |
| C. | DNA serves as a template for RNA |
| D. | mRNA is found in the ribosome |
| Answer» C. DNA serves as a template for RNA | |
| 43. |
The bacterial system has _____________ RNA polymerases. |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» D. 4 | |
| 44. |
Which of the following is not the part of the RNA polymerase core enzyme? |
| A. | α |
| B. | β |
| C. | ω |
| D. | σ |
| Answer» E. | |
| 45. |
What is the function of the ω subunit of RNA polymerase? |
| A. | Subunit association |
| B. | Promoter binding |
| C. | Initiation and elongation |
| D. | Cation binding |
| Answer» B. Promoter binding | |
| 46. |
Four types of σ factors are known of them which one is heat stable? |
| A. | σ70 |
| B. | σ32 |
| C. | σ54 |
| D. | σ28 |
| Answer» B. σ32 | |
| 47. |
The RNA polymerase core enzyme converts into a holoenzyme on the addition of the _________ subunit. |
| A. | α |
| B. | β |
| C. | β’ |
| D. | σ |
| Answer» E. | |
| 48. |
The β’ subunit of polymerase has a function of ________________ |
| A. | Promoter binding |
| B. | Elongation |
| C. | Cation binding |
| D. | Termination |
| Answer» D. Termination | |
| 49. |
Presence of the heparin promotes transcription. |
| A. | True |
| B. | False |
| Answer» C. | |
| 50. |
The β subunit of polymerase has a function of ____________ |
| A. | Promoter binding |
| B. | Catalytic center |
| C. | Template binding |
| D. | Cation binding |
| Answer» C. Template binding | |