Explore topic-wise MCQs in VITEEE.

This section includes 51 Mcqs, each offering curated multiple-choice questions to sharpen your VITEEE knowledge and support exam preparation. Choose a topic below to get started.

1.

The mechanism of action of cyanide, a mitochondrial toxin, is by inhibiting

A. ATP synthase
B. Succinate dehydrogenase
C. Cytochrome c oxidase
D. NADH dehydrogenase
Answer» D. NADH dehydrogenase
2.

 Mitochondrial DNA is one of the best marker tools for population biologists and evolutionary biologists because

A. Absence of genetic recombination in mt-DNA
B. Mitochondrial genes are specific to mt-DNA
C. It can be easily isolated
D. It undergoes spontaneous mutation
Answer» B. Mitochondrial genes are specific to mt-DNA
3.

Typically how many copies of DNA is/are there in each mitochondrion?

A. 1
B. 11
C. 10
D. 12
Answer» D. 12
4.

The size of plant mitochondrial DNA is

A. 16kb
B. 200-2500kb
C. 100- 2550kb
D. 100-2500kb
Answer» C. 100- 2550kb
5.

The size of human mitochondrial DNA is

A. 16kb
B. 200kb
C. 2500kb
D. 100kb
Answer» B. 200kb
6.

More than what proportion of mitochondrial proteins are coded by nuclear DNA?

A. 95%
B. 50%
C. 10%
D. 40%
Answer» B. 50%
7.

 Oxysomes or F0 – F1 particles occur on

A. Inner mitochondrial membrane
B. Chloroplast surface
C. Mitochondrial surface
D. Thylakoids
Answer» B. Chloroplast surface
8.

Mitochondrial DNA is a

A. Simple, single stranded linear DNA molecule
B. Simple, single stranded circular DNA molecule
C. Simple, double stranded linear DNA molecule
D. Simple, double stranded circular DNA molecule
Answer» E.
9.

How many mitochondrial proteins are encoded in nuclear genes and imported into mitochondria after their synthesis?

A. 600
B. 700
C. 800
D. 900
Answer» E.
10.

How many human mitochondrial proteins are encoded in the mitochondrial genome and synthesized within mitochondria?

A. 11
B. 12
C. 13
D. 1`4
Answer» D. 1`4
11.

The effect of increased levels of hydrogen ions in the inter-membrane space of the mitochondria is

A. Increase ATP production
B. Decreased levels of oxidative phosphorylation
C. Increased levels of water in inter-membrane space
D. Decreased levels of chemiosmosis
Answer» B. Decreased levels of oxidative phosphorylation
12.

Products of glucose oxidation essential for oxidative phosphorylation are

A. Pyruvate
B. Acetyl co-A
C. NADPH and ATP
D. NADH and FADH2
Answer» E.
13.

NADP+ in its reduced form is

A. NAD
B. NADH
C. NADPH
D. None
Answer» D. None
14.

What is the proportion of ATP produced by oxidative phosphorylation?

A. 60%
B. 70%
C. 80%
D. 90%
Answer» B. 70%
15.

NADP is a cofactor used in

A. Catabolic reactions
B. Anabolic reactions
C. Elimination reaction
D. Redox reactions
Answer» C. Elimination reaction
16.

In metabolism, NAD is involved in

A. Spontaneous reaction
B. Elimination reaction
C. Redox reactions
D. None
Answer» D. None
17.

Where does oxidative phosphorylation take place?

A. Ribosomes
B. Nucleus
C. Mitochondria
D. Cell membrane
Answer» D. Cell membrane
18.

The magnitude of proton motive force depends on

A. Energy charge of cell
B. Permeability of membrane
C. Number of ribosomes in cell
D. None
Answer» B. Permeability of membrane
19.

The rate of electron transfer when proton motive force is high is

A. Faster
B. Slower
C. Moderate
D. None
Answer» C. Moderate
20.

The regulation of oxidative phosphorylation depends on

A. Magnitude of ion motive force
B. Magnitude of electron motive force
C. Magnitude of proton motive force
D. None
Answer» D. None
21.

Maximum energy per gram on oxidation is yielded from

A. Starch
B. Fat
C. Glycogen
D. Protein
Answer» C. Glycogen
22.

Long-chain fatty acids are oxidized step-wise in one carbon units starting from

A. Carboxyl end
B. Aliphatic end
C. a and b
D. None
Answer» B. Aliphatic end
23.

Membrane potential and proton gradient

A. Cancel one another when uncouplers are present
B. Reinforce one another when respiratory inhibitors are present
C. Are sufficient, separately to make ATP from ADP + Pi
D. Are required to make ATP
Answer» E.
24.

Every cycle of β-oxidation produces

A. 1 FAD, 1 NAD+ and 2 CO2 molecules
B. 1 FADH2, 1 NADH and 1 acetyl co-A
C. 1 FADH2, 1 NAD+ and 1 acetyl co-A
D. 1 FAD, 1 NADH and 2 CO2 molecules
Answer» C. 1 FADH2, 1 NAD+ and 1 acetyl co-A
25.

The acyl co-A formed in the cytosol is transported to

A. Mitochondrial matrix
B. Microsomes
C. ER
D. Remains in cytosol
Answer» B. Microsomes
26.

Three identical β subunits of the F1 complex during ATP synthesis have

A. Different affinities for ATP and ADP
B. Similar affinities for ADP and ATP
C. Different affinities for ADP but not ATP
D. Different affinities for ATP but not ADP
Answer» B. Similar affinities for ADP and ATP
27.

The transport of acyl co-A for oxidation using a shuttle involves formation of the intermediate

A. Acyl coenzyme A
B. 3 acetyl co-A
C. Acyl cartinine
D. None
Answer» D. None
28.

The measure of potential energy stored as combination of proton and voltage gradients across membrane is termed as

A. Proton motive force
B. Electron motive force
C. Molecule motive force
D. Ion motive force
Answer» B. Electron motive force
29.

ATP synthesis by chemiosmosis is by

A. ATP dehydrogenase
B. Gyrase
C. ATP synthase
D. Dehydrogenase
Answer» D. Dehydrogenase
30.

The proposal of chemiosmotic hypothesis was by

A. Peter D. Mitchell
B. Charles Darwin
C. Mendele
D. Alfred Russell
Answer» B. Charles Darwin
31.

Which of the following accepts only one electron?

A. Cytochrome b
B. Coenzyme Q
C. FMN
D. FAD
Answer» B. Coenzyme Q
32.

Out of the following the one having highest redox potential is

A. Ubiquinone
B. O2
C. FMN
D. NAD
Answer» C. FMN
33.

Chemiosmotic hypothesis does not involve

A. Only proton transport is strictly regulated, other positively charged ions can diffuse freely across the mitochondrial membrane
B. ATPase activity is reversible
C. Proton flow in to the mitochondria depends on the presence of ADP and Pi
D. Electron transport by the respiratory chain pumps protons out of the mitochondria
Answer» B. ATPase activity is reversible
34.

Which of the following takes place in substrate level phosphorylation?

A. Oxidation of one molecule of substrate is linked to synthesis of more than one ATP molecule
B. High energy intermediate compounds cannot be isolated
C. Only mitochondrial reactions participate in ATP formation
D. Substrate reacts to form a product containing a high energy bond
Answer» E.
35.

If rotenone is added to the mitochondrial electron transport chain

A. Succinate oxidation remains normal
B. P: O ratio of NADH is reduced from 3:1 to 2:1
C. Oxidative phosphorylation is uncoupled at site I
D. Rate of NADH oxidation is diminished to two-thirds of its initial value
Answer» B. P: O ratio of NADH is reduced from 3:1 to 2:1
36.

If the oxidative phosphorylation was uncoupled in the mitochondria then there is a/an

A. Decreased concentration of ADP in the mitochondria
B. Decreased oxidative rate
C. Increased inorganic phosphate in the mitochondria
D. Decreased production of heat
Answer» D. Decreased production of heat
37.

 If the oxidative phosphorylation was uncoupled in the mitochondria then there is a/an

A. Decreased concentration of ADP in the mitochondria
B. Decreased oxidative rate
C. Increased inorganic phosphate in the mitochondria
D. Decreased production of heat
Answer» D. Decreased production of heat
38.

 If 2, 4-dinitrophenol is added to tightly coupled mitochondria that are actively oxidizing succinate

A. Electron flow will continue but ATP synthesis will not occur
B. Electron flow will continue but ATP synthesis will be increased
C. Electron flow will cease but ATP synthesis will continue
D. Both electron flow and ATP synthesis will be ceased
Answer» B. Electron flow will continue but ATP synthesis will be increased
39.

 If mitochondria were blocked at the site of NADH oxidation and were treated with succinate as substrate, what would the P : O ratio is?

A. Same as that normally produced by succinate
B. One more than normally produced by succinate
C. One less than normally produced by succinate
D. Zero
Answer» B. One more than normally produced by succinate
40.

Effect of valinomycin on oxidative phosphorylation does not involve

A. pH gradient across the inner mitochondrial membrane decreases
B. Rate of flow of electrons increases
C. Rate of oxygen consumption increases
D. Net yield of ATP decreases
Answer» B. Rate of flow of electrons increases
41.

Which of the following is the prosthetic group of NADH dehydrogenase?

A. NADH
B. FAD
C. NADPH
D. FMN
Answer» E.
42.

In mitochondria, hydride ions are removed from substrates by

A. NAD-linked dehydrogenases
B. NADP-linked dehydrogenases
C. ATP synthase
D. Succinate dehydrogenases
Answer» B. NADP-linked dehydrogenases
43.

Complex 4 is also called

A. NADH dehydrogenase
B. Succinate dehydrogenase
C. Cytochrome bc1 complex
D. Cytochrome oxidase
Answer» E.
44.

Complex 3 is also called

A. NADH dehydrogenase
B. Succinate dehydrogenase
C. Cytochrome bc1 complex
D. Cytochrome oxidase
Answer» D. Cytochrome oxidase
45.

Complex 2 is also called

A. NADH dehydrogenase
B. Succinate dehydrogenase
C. Cytochrome bc1 complex
D. Cytochrome oxidase
Answer» C. Cytochrome bc1 complex
46.

Complex 1 is also called

A. NADH dehydrogenase
B. Succinate dehydrogenase
C. Cytochrome bc1 complex
D. Cytochrome oxidase
Answer» B. Succinate dehydrogenase
47.

The first step in the β oxidation of fatty acyl co-A is catalyzed by

A. Succinate dehydrogenase
B. NADH dehydrogenase
C. ATP synthase
D. Acyl co-A dehydrogenase
Answer» E.
48.

The only membrane bound enzyme in the citric acid cycle is

A. Succinate dehydrogenase
B. NADH dehydrogenase
C. ATP synthase
D. Acyl co-A dehydrogenase
Answer» B. NADH dehydrogenase
49.

 A lipid-soluble benzoquinone with a long isoprenoid side chain

A. Ubiquinone
B. Cytochrome b
C. Cytochrome c
D. Cytochrome a
Answer» B. Cytochrome b
50.

NADP-linked dehydrogenase catalyzes

A. Glucose 6-phosphate+NADP+ ↔ 6-phosphogluconate + NADPH + H+
B. Lactate + NAD+ ↔ pyruvate + NADH + H+
C. Pyruvate + CoA + NAD+ ↔ acetyl-CoA + CO2 + NADH + H+
D. L-Malate + NAD+ ↔ oxaloacetate + NADH + H+
Answer» B. Lactate + NAD+ ↔ pyruvate + NADH + H+