With regard to pain pathways, all the following are true EXCEPT:

• A. peripheral afferents are transmitted along A (delta) and C fibres
• B. an intact cerebral cortex is necessary for pain sensation
• C. the synaptic transmitter released by primary afferent fibres subserving pain is substance P
• D. afferent fibres subserving pain sensation from viscera reach the CNS by both sympathetic and parasympathetic pathways
• E. the sensory organs for pain are marked nerve endings