Regarding renal innervation:

• A. transplanted kidneys initially have reduced concentrating ability because of lack of innervation of the juxtaglomerular cells and therefore decreased renin secretion
• B. norepinephrine acts directly on receptors on the juxtaglomerular cells
• C. renal blood flow increases during exercise
• D. autoregulation of renal blood flow can be disrupted by angiotensin-II inhibitors when renal perfusion is low