Regarding neuromuscular transmission, which statement is INCORRECT?

• A. smooth muscle cells possess synapses en passant
• B. about 10 times as much acetylcholine as is required is released at skeletal muscle neuromuscular junctions
• C. antibodies can develop to calcium channels in nerve endings at neuromuscular junctions
• D. more than one nerve fibre ends on each end-plate in skeletal muscle
• E. acetylcholine is released by exocytosis