MCQOPTIONS
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MCQOPTIONS
This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Protein Engineering knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following antibiotic acts by competitively inhibiting the peptidyl transferase activity of prokaryotic ribosomes? |
| A. | Puromycin |
| B. | Vancomycin |
| C. | Tetracycline |
| D. | Chloramphenicol |
| Answer» E. | |
| 2. |
The peptidyl transferase center that catalyzes the peptide bond formation is located on the smaller subunit and consists entirely of rRNA. |
| A. | True |
| B. | False |
| Answer» C. | |
| 3. |
First, the bond between the amino acid and the tRNA in the P site is cleaved, then the peptide bond is formed between the two amino acids. |
| A. | False |
| B. | True |
| Answer» C. | |
| 4. |
Which of the following proteins bind to the ribosome and causes the dissociation of the two ribosomal subunits from mRNA? |
| A. | RF 1 |
| B. | RF 2 |
| C. | RF 3 |
| D. | RRF |
| Answer» E. | |
| 5. |
With the help of which of the following proteins does the ribosome recognize the stop codon? |
| A. | Cleavage Factors (CF) |
| B. | Elimination Factors (EF) |
| C. | Termination Factors (TF) |
| D. | Release Factors (RF) |
| Answer» E. | |
| 6. |
Which of the following rRNA is intimately involved with the peptidyl transferase activity? |
| A. | 5S rRNA |
| B. | 16S rRNA |
| C. | 28S rRNA |
| D. | 23S rRNA |
| Answer» E. | |
| 7. |
The second and further aminoacyl-tRNAs are brought to the ribosome bound to which of the following protein complex? |
| A. | EF-Ts-ATP |
| B. | EF-Ts-GTP |
| C. | EF-Tu-ATP |
| D. | EF-Tu-GTP |
| Answer» E. | |
| 8. |
Which of the following initiation factor bring the initiator tRNA? |
| A. | IF-4 |
| B. | IF-3 |
| C. | IF-1 |
| D. | IF-2 |
| Answer» E. | |
| 9. |
Which of the following initiation factor when bound to the 30S subunit blocks the A site, so that only the P site is available for the initiator tRNA to bind to? |
| A. | IF-4 |
| B. | IF-2 |
| C. | IF-3 |
| D. | IF-1 |
| Answer» E. | |
| 10. |
Base pairing between mRNA and which of the following rRNAs help in the selection of translation initiation site? |
| A. | 5.8S rRNA |
| B. | 5S rRNA |
| C. | 28S rRNA |
| D. | 16S rRNA |
| Answer» E. | |
| 11. |
In prokaryotes and eukaryotes, multiple ribosomes can bind to a single mRNA transcript, and give rise to beads on a string structure. What is this structure called? |
| A. | Monosome |
| B. | Multiribosome |
| C. | Oligosome |
| D. | Polysome |
| Answer» E. | |
| 12. |
The ribosome reads mRNA in which of the following direction? |
| A. | Both 3 5 and 5 3 |
| B. | Either 3 5 or 5 3 |
| C. | 3 5 direction only |
| D. | 5 3 direction only |
| Answer» E. | |
| 13. |
In which of the following directions does the polypeptide synthesis proceeds? |
| A. | From both N-terminus and C-terminus |
| B. | Either from N-terminus or C-terminus |
| C. | C-terminus to N-terminus |
| D. | N-terminus to C-terminus |
| Answer» E. | |
| 14. |
What is the process of synthesis of a polypeptide chain from mRNA known as? |
| A. | Conversion |
| B. | Replication |
| C. | Transcription |
| D. | Translation |
| Answer» E. | |