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This section includes 9 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
1. |
Which of the following about the differences between the prokaryotic and eukaryotic genes are true? |
A. | Prokaryotic genes are large, polycistronic and contain enhancers |
B. | Eukaryotic genes are large, polycistronic and contain enhancers |
C. | Prokaryotic genes are large, monocistronic and contain introns |
D. | Eukaryotic genes are large, monocistronic and contain introns |
Answer» E. | |
2. |
The most commonly observed modification in the histone includes ___________ |
A. | Acetylation of lysine and phosphorylation of serine |
B. | Acetylation of lysine and phosphorylation of threonine |
C. | Acetylation of arginine and phosphorylation of threonine |
D. | Acetylation of arginine and phosphorylation of serine |
Answer» B. Acetylation of lysine and phosphorylation of threonine | |
3. |
Which of the following about the enhancer sequence is incorrect? |
A. | They are required for transcriptional regulation of some genes |
B. | They can work in both directions |
C. | They can work when present in any position of the DNA |
D. | They are not responsible for specificity of tissues |
Answer» E. | |
4. |
With respect to the methylation of bases which of the following is correct? |
A. | Protects against the action of S1 nuclease |
B. | Methyl groups are added to cystine in eukaryotic cells |
C. | It results in localized conversion of A-DNA to Z-DNA |
D. | Involved in translation |
Answer» D. Involved in translation | |
5. |
Acetylation of histone increases transcription of gene due to ___________ |
A. | Increase in the DNA-histone interaction |
B. | It loosens the DNA-histone complex thus making it accessible to RNA polymerase |
C. | It induces DNA blending which is recognized by RNA polymerase |
D. | The acetyl groups are recognizable by RNA polymerase |
Answer» C. It induces DNA blending which is recognized by RNA polymerase | |
6. |
Gene imprinting involves ___________ |
A. | DNA methylation |
B. | DNA phosphorylation |
C. | DNA glycosylation |
D. | DNA oxidation |
Answer» B. DNA phosphorylation | |
7. |
In the case of transcription regulation what is the function of enhancer molecules? |
A. | Helps initiate transcription |
B. | Transcription elongation |
C. | Stimulates the rate of transcription |
D. | mRNA stability enhancement |
Answer» D. mRNA stability enhancement | |
8. |
Which of the following about the enhancers is false? |
A. | They function in orientation |
B. | They function as promoter sequences |
C. | They work as both cis and trans-acting sequences |
D. | They are tissue specific |
Answer» C. They work as both cis and trans-acting sequences | |
9. |
Which of the following is not a target site for repressor molecules? |
A. | Activators |
B. | Mediators |
C. | Co-repressors |
D. | Promoter sites |
Answer» E. | |