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This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
1. |
Levene investigated and found that the nucleic acid is composed of poly-nucleotides and each nucleotide is composed of one base, a sugar molecule and a phosphate. This was performed on the genome of________________ |
A. | Bacteria |
B. | Fungi |
C. | WBCs |
D. | Yeast |
Answer» E. | |
2. |
The hydrogen bonds formed during A and T bonding occurs between C6NH2 of A and __________ |
A. | C4O of T |
B. | PO3– |
C. | C6O of A |
D. | C1O of T |
Answer» B. PO3– | |
3. |
What should be the complementary strand of 3’….ATGGCTTGA….5’? |
A. | 3’….TACCGAACT….5’ |
B. | 5’….TACCGAACT….3’ |
C. | 3’….TAGGCAAGT….5’ |
D. | 5’….TAGGCAAGT….3’ |
Answer» C. 3’….TAGGCAAGT….5’ | |
4. |
LEVENE_INVESTIGATED_AND_FOUND_THAT_THE_NUCLEIC_ACID_IS_COMPOSED_OF_POLY-NUCLEOTIDES_AND_EACH_NUCLEOTIDE_IS_COMPOSED_OF_ONE_BASE,_A_SUGAR_MOLECULE_AND_A_PHOSPHATE._THIS_WAS_PERFORMED_ON_THE_GENOME_OF________________?$ |
A. | Bacteria |
B. | Fungi |
C. | WBCs |
D. | Yeast |
Answer» E. | |
5. |
In the late 1970s non double helical form of DNA was also suggested but was discarded on the basis of certain factors. Which of the following is not a factor responsible? |
A. | X-ray crystallography |
B. | Nuclein |
C. | Topoisomerase |
D. | Nucleosome core particle |
Answer» C. Topoisomerase | |
6. |
With respect to the importance of hydrogen bonding and DNA double helix stability, which of the following statements is false? |
A. | Favorable tautomeric form of nucleotide bases |
B. | Contributes to the thermodynamic stability |
C. | Decreases the entropy |
D. | Specificity of base pairing |
Answer» D. Specificity of base pairing | |
7. |
It is easy to break the bond between A and T than in between G and C. |
A. | True |
B. | False |
Answer» B. False | |
8. |
In a DNA double helix the bases are held together by hydrogen bonds. These hydrogen bonds are _________ |
A. | Covalent bonds |
B. | Non-covalent bonds |
C. | Ionic bonds |
D. | Van der Waals forces |
Answer» C. Ionic bonds | |
9. |
The hydrogen bonds formed during A and T bonding occurs between C6NH2 of A and _____ |
A. | C4O of T |
B. | PO3<sup>–</sup> |
C. | C6O of A |
D. | C1O of T |
Answer» B. PO3<sup>‚Äö√Ñ√∂‚àö√ë‚àö¬®</sup> | |
10. |
What should be the complementary strand of 3’….ATGGCTTGA….5’?$ |
A. | 3’….TACCGAACT….5’ |
B. | 5’….TACCGAACT….3’ |
C. | 3’….TAGGCAAGT….5’ |
D. | 5’….TAGGCAAGT….3’ |
Answer» C. 3‚Äö√Ñ√∂‚àö√ë‚àö¬•‚Äö√Ñ√∂‚àö√묨‚àÇ.TAGGCAAGT‚Äö√Ñ√∂‚àö√묨‚àÇ.5‚Äö√Ñ√∂‚àö√ë‚àö¬• | |
11. |
In 1952, an unambiguous established work in the laboratory of Alexander Todd led to the discovery of _____________ |
A. | Chemical nature of DNA |
B. | X-ray diffraction structure of DNA |
C. | 3’-5’ phosphodiester linkage regularly links the nucleotides of DNA |
D. | Nucleic acid strands are held together by hydrogen bonds |
Answer» D. Nucleic acid strands are held together by hydrogen bonds | |
12. |
In early 1950s high quality X-ray diffraction photographs of DNA suggesting the DNA being double helix and composed of two nucleotide strands. Who took those photographs? |
A. | Rosalind Franklin |
B. | William Asbury |
C. | Francis H. Crick and James D. Watson |
D. | Rosalind Franklin and Maurice Wilkins |
Answer» E. | |
13. |
The first X-ray diffraction patterns of DNA were taken in 1938 by ___________ |
A. | William Asbury |
B. | Rosalind Franklin |
C. | Francis H. Crick |
D. | Linus Pauling |
Answer» B. Rosalind Franklin | |