MCQOPTIONS
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MCQOPTIONS
This section includes 12 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of these promoter elements has a high propensity of developing mutation given the eukaryotic gene was inserted in prokaryotes? |
| A. | CCAAT box |
| B. | CPG islands |
| C. | TATA box |
| D. | Enhancer |
| Answer» C. TATA box | |
| 2. |
Which of this element is not orientation independent? |
| A. | Enhancer |
| B. | Silencer |
| C. | Upstream activating element |
| D. | Promoter proximal elements |
| Answer» E. | |
| 3. |
WHICH_OF_THIS_ELEMENT_IS_NOT_ORIENTATION_INDEPENDENT??$ |
| A. | Enhancer |
| B. | Silencer |
| C. | Upstream activating element |
| D. | Promoter proximal elements |
| Answer» E. | |
| 4. |
Which_of_these_promoter_elements_has_a_high_propensity_of_developing_mutation_given_the_eukaryotic_gene_was_inserted_in_prokaryotes?$ |
| A. | CCAAT box |
| B. | CPG islands |
| C. | TATA box |
| D. | Enhancer |
| Answer» C. TATA box | |
| 5. |
If you make a chimeric factor with the DNA binding element of an activator and a functional domain of a repressor, how will this factor behave? |
| A. | It will act like a repressor |
| B. | It will act like an activator |
| C. | It will not be able to bind the DNA so although it binds via the repressing domain it won’t cause repression |
| D. | Repression domain will be non-functional |
| Answer» B. It will act like an activator | |
| 6. |
Which of these class III promoter type resemble class II? |
| A. | Type I |
| B. | Type II |
| C. | Type III |
| D. | Type IV |
| Answer» D. Type IV | |
| 7. |
Repressors are active only when they are at the proximity of the RNA polymerase as they directly associate with the pre-initiation complex. State whether this is true or false. |
| A. | True |
| B. | False |
| Answer» C. | |
| 8. |
Which would be an appropriate method to detect the core promoter regions in a eukaryotic gene? |
| A. | Footprint |
| B. | Sequencing |
| C. | Linker scanning |
| D. | S1 endonuclease |
| Answer» D. S1 endonuclease | |
| 9. |
Which of these is not a promoter element? |
| A. | TATA box |
| B. | DPE |
| C. | CCAAT box |
| D. | Inr |
| Answer» D. Inr | |
| 10. |
TFIIB can bind to a promoter element in the core promoter of eukaryotes. This element is __________ |
| A. | Inr |
| B. | BRE |
| C. | DPE |
| D. | TATA |
| Answer» C. DPE | |
| 11. |
TATA box in eukaryotes would be present in _________________ |
| A. | Housekeeping genes |
| B. | Developmentally regulated genes |
| C. | Cytoskeletal genes like that for actin |
| D. | Highly specialized genes. |
| Answer» E. | |
| 12. |
Promoter proximal elements is positioned ________________ |
| A. | Outside the core promoter |
| B. | Downstream to start site |
| C. | Within the enhancer |
| D. | Just before the start site |
| Answer» C. Within the enhancer | |