MCQOPTIONS
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This section includes 19 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
RNA pol II will be isolated from the nuclear parts outside the nucleolus. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 2. |
The rRNA primary transcript is located in________ |
| A. | Nucleus |
| B. | NOR |
| C. | Cytoplasm |
| D. | Nuclear pore |
| Answer» C. Cytoplasm | |
| 3. |
Which of the following is not a normal processing step of the tRNA? |
| A. | The 3’ end U is replaced by CCA |
| B. | The Purines are methylated and isopentyl groups are transferred to them |
| C. | The 3’ OH is methylated |
| D. | U bases at specific sites are converted to pseudo uridine, ribo thimidine or dihydrouridine |
| Answer» D. U bases at specific sites are converted to pseudo uridine, ribo thimidine or dihydrouridine | |
| 4. |
The 5’ end of the tRNA transcript is cleaved by____________ |
| A. | RNase K |
| B. | Exonuclease VII |
| C. | Endonucleace I |
| D. | Rnase P |
| Answer» E. | |
| 5. |
Which one of the following characters doesn’t go along with tRNA? |
| A. | Its primary transcript is processed by proteins |
| B. | The cleavage at the 5’ and 3’ end of the intron is simultaneous |
| C. | The introns are seen in yeast and they are larger than exons |
| D. | ATP and GTP hydrolysis joins the two RNA halves at the two ends of the introns |
| Answer» D. ATP and GTP hydrolysis joins the two RNA halves at the two ends of the introns | |
| 6. |
The pre-rRNA transcript transcribed by the RNA pol Idoesn’t include_________ |
| A. | 18S |
| B. | 5S |
| C. | 5.8S |
| D. | 28S |
| Answer» C. 5.8S | |
| 7. |
WHICH_OF_THE_FOLLOWING_IS_NOT_A_NORMAL_PROCESSING_STEP_OF_THE_TRNA??$ |
| A. | The 3’ end U is replaced by CCA |
| B. | The Purines are methylated and isopentyl groups are transferred to them |
| C. | The 3’ OH is methylated |
| D. | U bases at specific sites are converted to pseudo uridine, ribo thimidine or dihydrouridine |
| Answer» D. U bases at specific sites are converted to pseudo uridine, ribo thimidine or dihydrouridine | |
| 8. |
RNA pol II will be isolated from the nuclear parts outside the nucleolus.$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 9. |
The rRNA primary transcript is located in________$ |
| A. | Nucleus |
| B. | NOR |
| C. | Cytoplasm |
| D. | Nuclear pore |
| Answer» C. Cytoplasm | |
| 10. |
The 45S rRNA transcript is first broken into ______________ |
| A. | 32S and 20S |
| B. | 19S and 36S |
| C. | 6S and 40S |
| D. | 32S, 20s and 7S |
| Answer» B. 19S and 36S | |
| 11. |
The 5’ end of the tRNA transcript is cleaved by___________?# |
| A. | RNase K |
| B. | Exonuclease VII |
| C. | Endonucleace I |
| D. | Rnase P |
| Answer» E. | |
| 12. |
Which one of the following characters doesn’t go along with tRNA?$ |
| A. | Its primary transcript is processed by proteins |
| B. | The cleavage at the 5’ and 3’ end of the intron is simultaneous |
| C. | The introns are seen in yeast and they are larger than exons |
| D. | ATP and GTP hydrolysis joins the two RNA halves at the two ends of the introns |
| Answer» D. ATP and GTP hydrolysis joins the two RNA halves at the two ends of the introns | |
| 13. |
Bacterial pre rRNA transcript has ________________ |
| A. | 23S 4S 16S 5S |
| B. | 16S 4S 23S 5S |
| C. | 16S 5S 23S |
| D. | 23S 16S 5S |
| Answer» C. 16S 5S 23S | |
| 14. |
Which of the following is not a normal modification of the rRNA primary transcript? |
| A. | Conversion of U base to Pseudo uridine |
| B. | Methylation of the 2’- OH region of specific rRNA bases |
| C. | Cleavage of the intervening regions by exonucleases |
| D. | Proteins modulating the cleavage |
| Answer» E. | |
| 15. |
The cleavage of the rRNA is aided by the snRNA. |
| A. | True |
| B. | False |
| Answer» C. | |
| 16. |
The primary transcript is ______________ |
| A. | 52S |
| B. | 45S |
| C. | 32S |
| D. | 17S |
| Answer» C. 32S | |
| 17. |
The pre-rRNA transcript transcribed by the RNA pol Idoesn’t include_________$ |
| A. | 18S |
| B. | 5S |
| C. | 5.8S |
| D. | 28S |
| Answer» C. 5.8S | |
| 18. |
tRNA constitutes ___________ % of all RNA. |
| A. | 85 |
| B. | 25 |
| C. | 15 |
| D. | <5 |
| Answer» D. <5 | |
| 19. |
If you run the whole RNA extract on a gel you will get ____________ bands normally. |
| A. | Many |
| B. | One |
| C. | Two |
| D. | Three |
| Answer» D. Three | |