MCQOPTIONS
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MCQOPTIONS
This section includes 59 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following presents antigenic peptide to T-cells in order to initiate an adaptive immune response? |
| A. | Plasma cell |
| B. | Dendrite cell |
| C. | Neutrophil |
| D. | Epithelial cell |
| Answer» B. Dendrite cell | |
| 2. |
Which of the following bonds are not involved in tertiary type of protein structure? |
| A. | Disulfide bond |
| B. | Hydrogen bonding |
| C. | Salt bridges |
| D. | Hydrophilic interactions |
| Answer» E. | |
| 3. |
Which of the following is a function of Macrophages? |
| A. | Ingest large particles and cells by phagocytes |
| B. | Produce and secrete antibodies |
| C. | Interact with infected host cells through receptors on T-cell surface |
| D. | Interact with macrophages and secrete cytokines |
| Answer» B. Produce and secrete antibodies | |
| 4. |
Which of the following is a function of B lymphocytes? |
| A. | Ingest large particles and cells by phagocytes |
| B. | Produce and secrete antibodies |
| C. | Interact with infected host cells through receptors on T-cell surface |
| D. | Interact with macrophages and secrete cytokines |
| Answer» C. Interact with infected host cells through receptors on T-cell surface | |
| 5. |
In the binding of oxygen to myoglobin, the relationship between the concentration of oxygen and the fraction of binding sites occupied can best be described as ___________ |
| A. | Hyperbolic |
| B. | Linear with a negative slope |
| C. | Linear with a positive slope |
| D. | Parabolic |
| Answer» B. Linear with a negative slope | |
| 6. |
Myoglobin binding of O₂ depends on ___________ |
| A. | Hemoglobin concentration |
| B. | O₂ concentration and affinity of myoglobin for O₂ |
| C. | Ka |
| D. | Kd |
| Answer» C. Ka | |
| 7. |
IgG consists of ____________ |
| A. | A light chain and two heavy chains joined by a disulfide bond |
| B. | Two light chains and a heavy chain joined by a disulfide bond |
| C. | Two light chains and two heavy chains joined by a disulfide bond |
| D. | Two light chains and two heavy chains joined by hydrogen bond |
| Answer» D. Two light chains and two heavy chains joined by hydrogen bond | |
| 8. |
Process of folding does not depend on ____________ |
| A. | Concentration of salts |
| B. | pH |
| C. | Solute |
| D. | Solvent |
| Answer» D. Solvent | |
| 9. |
Which of the following is a function of chaperone protein? |
| A. | It degrades proteins that have folded improperly |
| B. | It provide a template for how the proteins should fold |
| C. | It rescues proteins that have folded improperly and allows them to refold properly |
| D. | It degrades proteins that have folded properly |
| Answer» D. It degrades proteins that have folded properly | |
| 10. |
Fibroin is rich in ________ |
| A. | Alanine and Glycine |
| B. | Alanine |
| C. | Glycine |
| D. | Pro |
| Answer» B. Alanine | |
| 11. |
Which of the following are chaperons in E.coli? |
| A. | Hsp70 |
| B. | Hsp40 |
| C. | DnaA |
| D. | DnaK and DnaJ |
| Answer» E. | |
| 12. |
Which of the following is a component of mitochondria? |
| A. | Ribonuclease |
| B. | Lysozyme |
| C. | Cytochrome c |
| D. | Myoglobin |
| Answer» D. Myoglobin | |
| 13. |
Which of the following cannot denature a protein? |
| A. | Iodoacetic acid |
| B. | SDS detergent |
| C. | Urea |
| D. | Heating to 90°C |
| Answer» B. SDS detergent | |
| 14. |
Which of the following contractile protein of skeletal muscle involve in ATPase activity? |
| A. | Troponin |
| B. | Myosin |
| C. | Tubulin |
| D. | Tropomyosin |
| Answer» C. Tubulin | |
| 15. |
Which of the following serves as bactericidal agent? |
| A. | Ribonuclease |
| B. | Lysozyme |
| C. | Cytochrome c |
| D. | Myoglobin |
| Answer» C. Cytochrome c | |
| 16. |
Which of the following forces is favorable for protein folding? |
| A. | Hydrophobic interactions |
| B. | Hydrogen bonding |
| C. | Vander Waals forces |
| D. | Ionic bonding |
| Answer» B. Hydrogen bonding | |
| 17. |
The cross bridges involved in muscle contraction are located on the __________ |
| A. | Myosin myofilaments |
| B. | Actin myofilaments |
| C. | Tropomyosin |
| D. | Dystrophin |
| Answer» B. Actin myofilaments | |
| 18. |
Protein A will fold into its native state only when protein B is also present in the solution. However, protein B can fold itself into native confirmation without the presence of protein A. Which of the following is true? |
| A. | Protein B serves as precursor for protein A |
| B. | Protein B serves as molecular chaperon for protein A |
| C. | Protein B serves as ligand for protein A |
| D. | Protein B serves as structural motif for protein A |
| Answer» C. Protein B serves as ligand for protein A | |
| 19. |
Which of the following enzyme is secreted by the pancreas? |
| A. | Ribonuclease |
| B. | Lysozyme |
| C. | Cytochrome c |
| D. | Myoglobin |
| Answer» B. Lysozyme | |
| 20. |
The most abundant immunoglobulin is ____________ |
| A. | IgA |
| B. | IgE |
| C. | IgG |
| D. | IgM |
| Answer» D. IgM | |
| 21. |
Which of the following is abundantly found in collagen? |
| A. | Glycine |
| B. | Serine |
| C. | Alanine |
| D. | Tryptophan |
| Answer» B. Serine | |
| 22. |
Which of the following is false about fibrous protein? |
| A. | It is in rod or wire like shape |
| B. | Keratin and collagen are the best examples |
| C. | Hemoglobin is the best example |
| D. | It provides structural support for cells and tissues |
| Answer» D. It provides structural support for cells and tissues | |
| 23. |
Which of the following is not the function of helper T cells is ____________ |
| A. | Produce soluble signaling proteins called cytokines, which include the interleukins |
| B. | They help activate cytotoxic T cells to kill infected target cells |
| C. | They help activate B cells to secrete antibodies and macrophages to destroy ingested microbes |
| D. | They recognize and bind extracellular ligands |
| Answer» E. | |
| 24. |
The primary antibody of exocrine secretions is ____________ |
| A. | IgA |
| B. | IgE |
| C. | IgG |
| D. | IgM |
| Answer» B. IgE | |
| 25. |
His⁹³ is also called ________ |
| A. | His F8 |
| B. | His F7 |
| C. | His F6 |
| D. | His F5 |
| Answer» B. His F7 | |
| 26. |
Which of the following is not a feature of secondary immune respone to an antigen when compared to the first immune response to the same antigen? |
| A. | Antibody is generated without T-cell help |
| B. | Antibody is generated fast |
| C. | Antibody produced has greater affinity for the antigen |
| D. | Much antibody is produced |
| Answer» B. Antibody is generated fast | |
| 27. |
Which of the following about spontaneous folding is false? |
| A. | It involves the initial formation of highly compact structure |
| B. | It involves initial formation of a local secondary structure |
| C. | It is essentially a random process |
| D. | It may be defective in some human diseases |
| Answer» D. It may be defective in some human diseases | |
| 28. |
Myoglobin and the subunits of hemoglobin have ___________ |
| A. | Very different primary and tertiary structures |
| B. | Very similar primary and tertiary structures |
| C. | Very similar primary structures, but different tertiary structures |
| D. | Very similar tertiary structures, but different primary structures |
| Answer» E. | |
| 29. |
Which of the following does not possess a quaternary structure? |
| A. | Myoglobin |
| B. | Lactate dehydrogenase |
| C. | Immunoglobin M |
| D. | Creatine Phospho Kinase |
| Answer» B. Lactate dehydrogenase | |
| 30. |
Contractile protein of a muscle is __________ |
| A. | Troponin |
| B. | Myosin |
| C. | Tubulin |
| D. | Tropomyosin |
| Answer» C. Tubulin | |
| 31. |
Light band has which of the following filament protein? |
| A. | Actin |
| B. | Myosin |
| C. | Actin and myosin |
| D. | Tubulin |
| Answer» B. Myosin | |
| 32. |
Which of the following is a correct relation? |
| A. | Ka [L] = [PL] ⁄ [P] |
| B. | Ka [L] = [P] ⁄ [PL] |
| C. | Ka [L] = [PL] × [P] |
| D. | Ka [PL] = [L] ⁄ [P] |
| Answer» B. Ka [L] = [P] ⁄ [PL] | |
| 33. |
As folding progresses which of the following does not take place? |
| A. | Entropy decreases |
| B. | Amount of protein in native state increases |
| C. | Free energy increases |
| D. | Amount of protein in native state decreases |
| Answer» E. | |
| 34. |
Which of the following is first determined as oligomer? |
| A. | Myoglobin |
| B. | Collagen |
| C. | Keratin |
| D. | Hemoglobin |
| Answer» E. | |
| 35. |
Which of the following is a function of T lymphocytes? |
| A. | Ingest large particles and cells by phagocytes |
| B. | Produce and secrete antibodies |
| C. | Interact with infected host cells through receptors on T-cell surface |
| D. | Interact with macrophages and secrete cytokines |
| Answer» D. Interact with macrophages and secrete cytokines | |
| 36. |
Which of the following is true about ribonucease? |
| A. | Native state which is catalytically inactive is denatured |
| B. | Unfolded state is inactive |
| C. | Renatured ribonuclease is inactive |
| D. | Renaturation involves reestablishment of the correct disulfide cross links |
| Answer» B. Unfolded state is inactive | |
| 37. |
A process by which a protein structure assumes its functional shape or conformation is? |
| A. | Denaturing |
| B. | Folding |
| C. | Synthesis |
| D. | Hydrolysis |
| Answer» C. Synthesis | |
| 38. |
Myoglobin is particularly abundant in ________ |
| A. | Nerves |
| B. | Muscles |
| C. | Blood cells |
| D. | Skin |
| Answer» C. Blood cells | |
| 39. |
The contractile unit consisting of bundles of thick filaments interleaved at either end with those of thin filaments is? |
| A. | Myofibril |
| B. | Cross bridges |
| C. | Z band |
| D. | Sarcomere |
| Answer» E. | |
| 40. |
When oxygen binds to a heme-containing protein, the two open coordination bonds of Fe²⁺ are occupied by___________ |
| A. | One O atom and one amino acid atom |
| B. | One O₂ molecule and one amino acid atom |
| C. | One O₂ molecule and one heme atom |
| D. | Two O atoms |
| Answer» C. One O₂ molecule and one heme atom | |
| 41. |
The interactions of ligands with proteins are ___________ |
| A. | Relatively nonspecific |
| B. | Relatively rare in biological systems |
| C. | Usually irreversible |
| D. | Usually transient |
| Answer» E. | |
| 42. |
Which of the following is the smallest division? |
| A. | Actin |
| B. | Fiber |
| C. | Fibril |
| D. | Filament |
| Answer» B. Fiber | |
| 43. |
Sarcomere is a part between __________ |
| A. | 2 I bands |
| B. | 2 Z bands |
| C. | 2 A bands |
| D. | 2 H bands |
| Answer» C. 2 A bands | |
| 44. |
The connective tissue that surrounds individual fibers is __________ |
| A. | Fascia |
| B. | Epimysium |
| C. | Endomysium |
| D. | Perimysium |
| Answer» D. Perimysium | |
| 45. |
Which of the following is an invagination of the muscle cell’s sarcolemma? |
| A. | Cisternae |
| B. | Microtubules |
| C. | T tubules |
| D. | Sarcoplasmic reticula |
| Answer» D. Sarcoplasmic reticula | |
| 46. |
Where do T-lymphocytes develop into fully competent but not activated T-cells? |
| A. | The thymus gland |
| B. | The lymph nodes |
| C. | The thyroid gland |
| D. | The bone marrow |
| Answer» B. The lymph nodes | |
| 47. |
Which of the following is the largest immunoglobulin? |
| A. | IgA |
| B. | IgE |
| C. | IgG |
| D. | IgM |
| Answer» E. | |
| 48. |
Which of the following antibody first reaches the site of infection? |
| A. | IgA |
| B. | IgE |
| C. | IgG |
| D. | IgM |
| Answer» E. | |
| 49. |
The antibody present in secretions like tears and saliva is ____________ |
| A. | IgA |
| B. | IgE |
| C. | IgG |
| D. | IgM |
| Answer» B. IgE | |
| 50. |
Which of the following are known as helix breakers? |
| A. | Proline and glycine |
| B. | Isoleucine and leucine |
| C. | Valine |
| D. | Threonine |
| Answer» B. Isoleucine and leucine | |