MCQOPTIONS
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MCQOPTIONS
This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Protein Engineering knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following is a feature of DNA-binding sites for regulatory proteins? |
| A. | Cytosine rich sequence |
| B. | Guanine rich sequence |
| C. | C<sub>p</sub>G repeats |
| D. | Palindromic sequence |
| Answer» E. | |
| 2. |
What is the approximate length of DNA-binding domains of regulatory proteins? |
| A. | 100-500 amino acid residues |
| B. | 50-60 amino acid residues |
| C. | 5-10 amino acid residues |
| D. | 60-90 amino acid residues |
| Answer» E. | |
| 3. |
The side chains of which amino acid residues are not hydrogen-bonded to bases in the DNA? |
| A. | Gln residue |
| B. | Lys residue |
| C. | Glu residue |
| D. | Ala residue |
| Answer» E. | |
| 4. |
Most regulatory proteins have discrete DNA-binding domains, which contain one or more relatively small groups. What are these groups called? |
| A. | Excretory motifs |
| B. | Regulatory motifs |
| C. | Catalytic motifs |
| D. | Structural motifs |
| Answer» E. | |
| 5. |
Zinc fingers do not have a role in which of the following processes? |
| A. | Transcriptional regulation |
| B. | Ubiquitin-mediated protein degradation |
| C. | Signal transduction |
| D. | Cellular transport |
| Answer» E. | |
| 6. |
Zinc fingers are not able to interact with which of the following? |
| A. | DNA |
| B. | RNA |
| C. | Poly-ADP-ribose |
| D. | ATP |
| Answer» E. | |
| 7. |
Which of the following is not true for zinc fingers? |
| A. | It contains a beta-sheet domain |
| B. | It contains an alpha-helix domain |
| C. | It contains Zn<sup>+2</sup> ion |
| D. | It contains Ca<sup>+2</sup> ion |
| Answer» E. | |
| 8. |
Zinc fingers in found in many eukaryotic DNA-binding motifs. |
| A. | False |
| B. | True |
| Answer» C. | |
| 9. |
Zinc fingers can also function as which of the following? |
| A. | Lipid-binding motif |
| B. | Carbohydrate-binding motif |
| C. | Ribosome-binding motif |
| D. | RNA-binding motif |
| Answer» E. | |
| 10. |
The interaction of a single zinc finger with DNA is typically very strong. |
| A. | True |
| B. | False |
| Answer» C. | |
| 11. |
What is the average length of the elongated loop in zinc fingers? |
| A. | 20 amino acid residues |
| B. | 10 amino acid residues |
| C. | 40 amino acid residues |
| D. | 30 amino acid residues |
| Answer» E. | |
| 12. |
Zn+2 ions in zinc fingers are coordinated to which amino acid residues? |
| A. | 2 Met and 2 Cys |
| B. | 4 Val or 2 Met and 2 Cys |
| C. | 2 Ala and 2 Gly |
| D. | 4 Cys or 2 Cys and 2 His |
| Answer» E. | |
| 13. |
The positively charged Zn+2 ion in the zinc finger interacts directly with the negatively charged phosphate in DNA. |
| A. | True |
| B. | False |
| Answer» C. | |
| 14. |
Which among the following motifs contain a positively charged ion? |
| A. | Leucine zippers |
| B. | H-T-H motif |
| C. | Homeobox |
| D. | Zinc fingers |
| Answer» E. | |
| 15. |
Regulatory proteins have only protein-DNA interacting domains. |
| A. | True |
| B. | False |
| Answer» C. | |