MCQOPTIONS
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MCQOPTIONS
This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Protein Engineering knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Ras proteins (a GTPase superfamily) are anchored to the plasma membrane by which of the following? |
| A. | GPI anchors |
| B. | Methylation |
| C. | Acylation |
| D. | Prenylation |
| Answer» E. | |
| 2. |
Which of the following anchors help in the attachment of proteins to the plasma membrane, specifically on the cytosolic leaflet? |
| A. | GPI anchors |
| B. | Acylation and GPI anchors |
| C. | Prenylation and GPI anchors |
| D. | Acylation and prenylation |
| Answer» E. | |
| 3. |
GPI anchors are glycolipids. |
| A. | False |
| B. | True |
| Answer» C. | |
| 4. |
Which of the following is not a lipid-anchored protein? |
| A. | Ras proteins |
| B. | Thy-1 |
| C. | PLAP |
| D. | Glycophorin |
| Answer» E. | |
| 5. |
A group of cytosolic proteins is anchored to the membrane by a hydrocarbon chain. This hydrocarbon chain is attached to which amino acid residue? |
| A. | Lysine |
| B. | Tyrosine |
| C. | Alanine |
| D. | Cysteine |
| Answer» E. | |
| 6. |
Some specialized proteins with distinctive covalently attached polysaccharides called proteoglycans are bound to the exoplasmic face of the plasma membrane by which of the following? |
| A. | Fatty acyl groups |
| B. | Prenyl groups |
| C. | Methyl groups |
| D. | GPI anchors |
| Answer» E. | |
| 7. |
What is the modification in which a hydrocarbon chain is attached to an amino acid residue on a protein which helps it anchor onto the plasma membrane? |
| A. | Ubiquitination |
| B. | Acetylation |
| C. | Methylation |
| D. | Prenylation |
| Answer» E. | |
| 8. |
Which of the following is necessary and sufficient for the binding of proteins to the membrane? |
| A. | N-terminal methionine |
| B. | Hydrophobic amino acid residues |
| C. | Several sugar groups |
| D. | GPI anchors |
| Answer» E. | |
| 9. |
Which of the following fatty acyl groups can be covalently attached to a protein so that it can get anchored to the plasma membrane? |
| A. | Acyl carnitine |
| B. | Stearic acid |
| C. | Linoleic acid |
| D. | Palmitate |
| Answer» E. | |
| 10. |
Which of the following process is not associated with lipid-anchored proteins? |
| A. | Acylation |
| B. | Prenylation |
| C. | GPI anchor linking |
| D. | Methylation |
| Answer» E. | |
| 11. |
The lipid anchors used to anchor proteins to the cytosolic face are not used for the exoplasmic face, and vice versa. |
| A. | False |
| B. | True |
| Answer» C. | |
| 12. |
A group of cytosolic proteins is anchored to the cytoplasmic face of a membrane by a fatty acyl group attached to an amino acid at the N-terminal. Which of the following is that amino acid? |
| A. | Tryptophan |
| B. | Alanine |
| C. | Methionine |
| D. | Glycine |
| Answer» E. | |
| 13. |
Which class of proteins is shown in the figure below? |
| A. | Cytosolic proteins |
| B. | Peripheral membrane proteins |
| C. | Integral membrane proteins |
| D. | Lipid-anchored proteins |
| Answer» E. | |
| 14. |
The polypeptide chain of lipid anchored proteins itself enter the phospholipid bilayer. |
| A. | True |
| B. | False |
| Answer» C. | |
| 15. |
Which of the following proteins are bound covalently to one or more lipid molecules in the plasma membrane? |
| A. | Peripheral membrane proteins |
| B. | Cytosolic proteins |
| C. | Intrinsic proteins |
| D. | Lipid-anchored proteins |
| Answer» E. | |