MCQOPTIONS
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MCQOPTIONS
This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Protein Engineering knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The basic residues in the DNA-binding domain of leucine zippers interact with which of the following position in the DNA? |
| A. | Minor groove and sequence-independent manner |
| B. | Major groove and sequence-independent manner |
| C. | Minor groove and sequence-dependent manner |
| D. | Major groove and sequence-dependent manner |
| Answer» E. | |
| 2. |
Leucine zippers are present only in eukaryotic regulatory proteins? |
| A. | True |
| B. | False |
| Answer» C. | |
| 3. |
Which of the following DNA-binding motif is also known as leucine scissors? |
| A. | Homeodomain |
| B. | H-T-H motif |
| C. | Zinc fingers |
| D. | Leucine zipper |
| Answer» E. | |
| 4. |
Which of the following region of the alpha-helix in leucine zippers is amphipathic? |
| A. | Either C or N terminus |
| B. | Both C and N terminus |
| C. | N terminus |
| D. | C terminus |
| Answer» E. | |
| 5. |
The leucine zipper is a left-handed parallel dimeric coiled-coil. |
| A. | False |
| B. | True |
| Answer» C. | |
| 6. |
The B-ZIP (basic-region leucine zipper) class of eukaryotic transcription factors contain which of the following DNA-binding motif? |
| A. | Homeodomain |
| B. | Zinc fingers |
| C. | H-T-H motif |
| D. | Leucine zipper |
| Answer» E. | |
| 7. |
The amino acid leucine is critical for the functioning of which motifs? |
| A. | H-T-H motif |
| B. | Homeodomain |
| C. | Zinc fingers |
| D. | Leucine zipper |
| Answer» E. | |
| 8. |
In leucine zippers, the DNA-binding region and the protein-binding region are the same. |
| A. | True |
| B. | False |
| Answer» C. | |
| 9. |
The two alpha-helices of the leucine zipper are present on different subunits of a dimeric regulatory protein. |
| A. | False |
| B. | True |
| Answer» C. | |
| 10. |
In the zipper region of leucine zippers, what is the occurrence of leucine residues? |
| A. | At every 9<sup>th</sup> position |
| B. | At every 11<sup>th</sup> position |
| C. | At every 4<sup>th</sup> position |
| D. | At every 7<sup>th</sup> position |
| Answer» E. | |
| 11. |
The DNA-binding domain of regulatory proteins (having leucine zippers) are rich in which amino acid residues? |
| A. | Met or Ala |
| B. | Gly or Trp |
| C. | His or Cys |
| D. | Lys or Arg |
| Answer» E. | |
| 12. |
Which of the following motifs form a coiled-coil? |
| A. | Zinc fingers |
| B. | Homeodomain |
| C. | H-T-H motif |
| D. | Leucine zipper |
| Answer» E. | |
| 13. |
Leucine residues in the leucine zipper do not interdigitate. |
| A. | False |
| B. | True |
| Answer» C. | |
| 14. |
Which of the following motif contains an amphipathic alpha-helix with a series of hydrophobic amino acid residues on one side? |
| A. | Homeodomain |
| B. | Zinc fingers |
| C. | H-T-H motif |
| D. | Leucine zipper |
| Answer» E. | |