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This section includes 23 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Name the antibiotic which inhibits protein synthesis in eukaryotes? |
| A. | Penicillin |
| B. | Cycloheximide |
| C. | Cinhonine |
| D. | Chlorophenicol |
| Answer» C. Cinhonine | |
| 2. |
Name the site where secreted protein synthesized? |
| A. | ER membrane bound ribosomes |
| B. | Mitochondrial ribosome |
| C. | Membrane free ribosome |
| D. | Chloroplast ribosome |
| Answer» B. Mitochondrial ribosome | |
| 3. |
Which of the following transport involves translocation of the protein from cytosol to the nucleus? |
| A. | Transmembrane transport |
| B. | Vesicular transport |
| C. | Non-gated transport |
| D. | Gated transport |
| Answer» E. | |
| 4. |
Which of the following statement is defines polysomes? |
| A. | Lysosomal aggregation |
| B. | Multiple units of ribosomes |
| C. | Attachment of many ribosomes to common mRNA |
| D. | Attachment of many mRNA to ribosomes |
| Answer» D. Attachment of many mRNA to ribosomes | |
| 5. |
Which of the following is not a sorting signal present of protein? |
| A. | Signal patch |
| B. | Signal peptide |
| C. | Carbohydrate sequence |
| D. | Amino acid sequence |
| Answer» D. Amino acid sequence | |
| 6. |
Which of the following Scientist discovered ribosome for the first time? |
| A. | George Emil Palade |
| B. | Theodor Schwann |
| C. | Antonie van Leeuwenhoek |
| D. | Robert Hook |
| Answer» B. Theodor Schwann | |
| 7. |
What is the sedimentation coefficient of mitochondrial ribosome of humans? |
| A. | 70S |
| B. | 55S |
| C. | 80S |
| D. | 60S |
| Answer» C. 80S | |
| 8. |
Which of the following ribosomal RNA does not take part in rDNA organization of E.coli? |
| A. | 5S RNA |
| B. | 23S RNA |
| C. | 16S RNA |
| D. | 5.8S RNA |
| Answer» E. | |
| 9. |
Eukaryotes have 80S ribosome. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 10. |
Genetic information stored in mRNA is translated to polypeptide by ___________ |
| A. | Ribosome |
| B. | Nucleus |
| C. | Endoplasmic reticulum |
| D. | Golgi apparatus |
| Answer» B. Nucleus | |
| 11. |
METHIONINE_AMINO_PEPTIDASE_WILL_REMOVE_THE_N_TERMINAL_FORMYL_METHIONINE_IF_THE_N+1_AMINO_ACID_IS_________?$ |
| A. | Glycine |
| B. | Phenyl alanine |
| C. | Methionine |
| D. | Tyrosine |
| Answer» B. Phenyl alanine | |
| 12. |
The 50S ribosomal subunit is folded in ______ major domains.$ |
| A. | 20 |
| B. | 4 |
| C. | 10 |
| D. | 6 |
| Answer» E. | |
| 13. |
The_f-Met_tRNA_binds_to_ribosomal_________site$ |
| A. | P |
| B. | A |
| C. | E |
| D. | G |
| Answer» B. A | |
| 14. |
The Shine and Dalgarno is located in ____________ |
| A. | 5.8S rRNA ~ 20 nucleotide upstream to start site |
| B. | mRNA ~ 10 nucleotide upstream to start site |
| C. | 16S rRNA ~ 10 nucleotide upstream to start site |
| D. | 23S rRNA ~ 10 nucleotide upstream to start site |
| Answer» D. 23S rRNA ~ 10 nucleotide upstream to start site | |
| 15. |
State_whether_the_enzyme_PDF_is_a_novel_drug_target_for_antibiotics. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 16. |
Which metal acts as a cofactor for Methionyl aminopeptidase? |
| A. | Mg<sup>2+</sup> |
| B. | Zn<sup>2+</sup> |
| C. | Co<sup>2+</sup> |
| D. | Mn<sup>2+</sup> |
| Answer» D. Mn<sup>2+</sup> | |
| 17. |
The tRNA f-Met-tRNA binds to __________ |
| A. | Formyl methinone |
| B. | Formic acid |
| C. | Metionine |
| D. | Glutamine |
| Answer» D. Glutamine | |
| 18. |
The ribosomal peptidyl transferase transfers ___________ |
| A. | An isolated amino acid to the peptide chain |
| B. | A peptide chain to an amino acid |
| C. | A peptide chain to another peptide chain |
| D. | An amino acid to a tRNA |
| Answer» C. A peptide chain to another peptide chain | |
| 19. |
Which ribosome recognized the transcription initiation site of the mRNA? |
| A. | 23S |
| B. | 5S |
| C. | 5.8S |
| D. | 18S |
| Answer» E. | |
| 20. |
Which of this is not a ribosomal protein? |
| A. | L21 |
| B. | S34 |
| C. | L4 |
| D. | S21 |
| Answer» C. L4 | |
| 21. |
If you gradually decrease the Mg2+ concentration of the solution of ribosomes, what will you expect? |
| A. | The subunits will associate faster |
| B. | The subunits will dissociate |
| C. | rRNA will separate from its protein |
| D. | The two subunits will dissociate into its rRNA |
| Answer» C. rRNA will separate from its protein | |
| 22. |
Which of these is transcribed by RNA pol III? |
| A. | 28S |
| B. | 16S |
| C. | 5.8S |
| D. | 5S |
| Answer» E. | |
| 23. |
Eukaryotic ribosomal subunits are _____________ |
| A. | 30S and 50S |
| B. | 30S and 50S |
| C. | 40S and 60S |
| D. | 30S and 60S |
| Answer» D. 30S and 60S | |