MCQOPTIONS
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MCQOPTIONS
This section includes 10 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
6, 4 PP are brought about by which type of mutagen? |
| A. | Methylase |
| B. | Phosphatase |
| C. | Radiation |
| D. | Base Analogue |
| Answer» D. Base Analogue | |
| 2. |
Mut H acts as ______________ |
| A. | Adaptor |
| B. | Exonuclease |
| C. | Endonuclease |
| D. | Helicase |
| Answer» D. Helicase | |
| 3. |
Which of the following mismatches will be ignored by MMR? |
| A. | A—C |
| B. | T—T |
| C. | G—T |
| D. | C—C |
| Answer» E. | |
| 4. |
Which of the following disease in humans is due to the error in MMR? |
| A. | Lynch syndrome |
| B. | Xeroderma Pigmentosum |
| C. | Cockyne’s syndrome |
| D. | Trichothio dystrophy |
| Answer» B. Xeroderma Pigmentosum | |
| 5. |
Which MMR protein homologue has not yet been discovered in eukaryotes? |
| A. | Mut L |
| B. | Mut H |
| C. | Mut S |
| D. | Rec J |
| Answer» C. Mut S | |
| 6. |
If the nick is at 5’ end of the mismatch which of the following will be recruited? |
| A. | Rec J |
| B. | Ruv D |
| C. | Exonuclease I |
| D. | Exonuclease X |
| Answer» E. | |
| 7. |
Which of the following factors in MMR can recognize the mismatch? |
| A. | Mut L |
| B. | Mut S |
| C. | Mut H |
| D. | XRCC1 |
| Answer» C. Mut H | |
| 8. |
In an experiment you make two setups, in 1st you knock down the DAM and in 2nd you over express DAM. What will be the observation for both the setups? |
| A. | In 1st case BER is compromised and in 2nd MMR is compromised |
| B. | In 1st case MMR is compromised, while in 2nd MMR is more accurate |
| C. | In both cases MMR is compromised |
| D. | In both cased BER is compromised |
| Answer» D. In both cased BER is compromised | |
| 9. |
DNA microsatellites are prone to which type of mutation? |
| A. | Transition |
| B. | Transversion |
| C. | Addition |
| D. | Methylation |
| Answer» D. Methylation | |
| 10. |
Which of the following modes of repair is restricted to S phase of the cell cycle? |
| A. | BER |
| B. | MMR |
| C. | NER |
| D. | DSB |
| Answer» C. NER | |