 
			 
			MCQOPTIONS
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				This section includes 17 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Passage of a cell through stages of cell cycle is controlled by a protein kinase that phosphorylates many different proteins at appropriate times. | 
| A. | Cdk activating kinase | 
| B. | Cyclin-dependent kinase | 
| C. | Cyclins | 
| D. | Tyrosine kinase | 
| Answer» C. Cyclins | |
| 2. | Which of the following occurs in meiosis but not in mitosis? | 
| A. | Attachment of spindle fibers to kinetochore | 
| B. | Replication of DNA prior to start of cell division | 
| C. | Separation of sister chromatids at anaphase | 
| D. | Pairing of homologous chromosomes at metaphase plate | 
| Answer» E. | |
| 3. | At which cell cycle checkpoint, cell cycle is halted if cell’s DNA is damaged? | 
| A. | G1 – S | 
| B. | S – G2 | 
| C. | G2 – M | 
| D. | G0 – G1 | 
| Answer» B. S – G2 | |
| 4. | At the end of each phase of cell cycle cyclins activating Cdks in that phase are inactivated irreversibly by _____________ | 
| A. | Multiple phosphorylations | 
| B. | De-phosphorylation | 
| C. | Ubiquitinylation | 
| D. | Destabilizing by proteolysis in a proteosome | 
| Answer» E. | |
| 5. | Cyclin dependent kinases which control progression through cell cycle checkpoints are totally activated by which of the following? | 
| A. | Binding to cyclin, plus phosphorylation by a Cdk activating protein kinase | 
| B. | Binding to cyclins | 
| C. | Phosphorylation by Cdk activating protein kinase | 
| D. | Phosphorylation by a tyrosine kinase | 
| Answer» B. Binding to cyclins | |
| 6. | Cdk2/cyclinE functions in ____________ | 
| A. | G2/M transition | 
| B. | G2 | 
| C. | M | 
| D. | G1/S transition | 
| Answer» E. | |
| 7. | What is Ubiquitin? | 
| A. | Protein kinase | 
| B. | Protease | 
| C. | Component of the electron transport system | 
| D. | Protein that tags another protein for proteolysis | 
| Answer» E. | |
| 8. | WHICH_OF_THE_FOLLOWING_OCCURS_IN_MEIOSIS_BUT_NOT_IN_MITOSIS??$ | 
| A. | Attachment of spindle fibers to kinetochore | 
| B. | Replication of DNA prior to start of cell division | 
| C. | Separation of sister chromatids at anaphase | 
| D. | Pairing of homologous chromosomes at metaphase plate | 
| Answer» E. | |
| 9. | Passage_of_a_cell_through_stages_of_cell_cycle_is_controlled_by_a_protein_kinase_that_phosphorylates_many_different_proteins_at_appropriate_times$ | 
| A. | Cdk activating kinase | 
| B. | Cyclin-dependent kinase | 
| C. | Cyclins | 
| D. | Tyrosine kinase | 
| Answer» C. Cyclins | |
| 10. | At which cell cycle checkpoint, cell cycle is halted if cell’s DNA is damage?# | 
| A. | G<sub>1</sub> – S | 
| B. | S – G<sub>2</sub> | 
| C. | G<sub>2</sub> – M | 
| D. | G<sub>0</sub> – G<sub>1</sub> | 
| Answer» B. S ‚Äö√Ñ√∂‚àö√ë‚àö¬® G<sub>2</sub> | |
| 11. | At the end of each phase of cell cycle cyclins activating Cdks in that phase are inactivated irreversibly by | 
| A. | Multiple phosphorylations | 
| B. | De-phosphorylation | 
| C. | Ubiquitinylation | 
| D. | Destabilizing by proteolysis in a proteosome | 
| Answer» E. | |
| 12. | Cyclin dependent kinases which control progression through cell cycle checkpoints are totally activated by which of the following | 
| A. | Binding to cyclin, plus phosphorylation by a Cdk activating protein kinase | 
| B. | Binding to cyclins | 
| C. | Phosphorylation by Cdk activating protein kinase | 
| D. | Phosphorylation by a tyrosine kinase | 
| Answer» B. Binding to cyclins | |
| 13. | In which phase of cell cycle is DNA replicated? | 
| A. | G<sub>1</sub> phase | 
| B. | S phase | 
| C. | G<sub>2</sub> phase | 
| D. | M phase | 
| Answer» C. G<sub>2</sub> phase | |
| 14. | Cdk2/cyclinE functions in | 
| A. | G<sub>2</sub>/M transition | 
| B. | G<sub>2</sub> | 
| C. | M | 
| D. | G<sub>1</sub>/S transition | 
| Answer» E. | |
| 15. | Ubiquitin is a | 
| A. | Protein kinase | 
| B. | Protease | 
| C. | Component of the electron transport system | 
| D. | Protein that tags another protein for proteolysis | 
| Answer» E. | |
| 16. | Which of the following statements regarding cyclins is not correct? | 
| A. | They can become linked to ubiquitin | 
| B. | They catalyze the phosphorylation of protein | 
| C. | They contain specific amino acid sequence that target them for proteolysis | 
| D. | They are activated and degraded during cell cycle | 
| Answer» E. | |
| 17. | Which of the following statements regarding cyclin-dependent protein kinase is not correct? | 
| A. | Their activity is regulated by cyclins | 
| B. | They can alter the activity of proteins involve in the progression of cells through cell cycle | 
| C. | Their activity fluctuates during cell cycle | 
| D. | Each type of cell contains one specific form | 
| Answer» D. Each type of cell contains one specific form | |