 
			 
			MCQOPTIONS
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				This section includes 18 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Ras protein is a ____________ | 
| A. | G-protein switch | 
| B. | Small monomeric GTPase switch protein | 
| C. | Serine-threonine kinase | 
| D. | Tyrosine kinase | 
| Answer» C. Serine-threonine kinase | |
| 2. | Which of the following is a short-lived messenger that acts by stimulating a soluble guanylyl cyclase, raising [cGMP] and stimulating PKG? | 
| A. | NO | 
| B. | NO2 | 
| C. | NO3– | 
| D. | N2O | 
| Answer» B. NO2 | |
| 3. | Which of the following is not responsible of producing diarrhea? | 
| A. | Elevation in [cGMP] | 
| B. | Increase in Cl– secretion | 
| C. | Decrease in reabsorption of water by the intestinal epithelium | 
| D. | Decrease in Cl– secretion | 
| Answer» E. | |
| 4. | cGMP-dependent protein kinase is also called ____________ | 
| A. | Protein kinase B | 
| B. | Protein kinase A | 
| C. | Protein kinase G | 
| D. | Protein kinase C | 
| Answer» D. Protein kinase C | |
| 5. | Activation of guanylyl cyclase produces ____________ | 
| A. | Guanosine 3’, 5’-cyclic monophosphate | 
| B. | Guanosine 2’, 5’-cyclic monophosphate | 
| C. | Guanosine 4’, 5’-cyclic monophosphate | 
| D. | Guanosine 1’, 5’-cyclic monophosphate | 
| Answer» B. Guanosine 2’, 5’-cyclic monophosphate | |
| 6. | Protein kinase ERK is activated by phosphorylation of ____________ | 
| A. | Only Thr | 
| B. | Only Tyr | 
| C. | Both Thr and Tyr | 
| D. | Only Ser | 
| Answer» D. Only Ser | |
| 7. | The enzyme activated by cyclic AMP, passing on the hormonal signal is ____________ | 
| A. | Protein kinase B | 
| B. | Protein kinase A | 
| C. | Protein kinase C | 
| D. | G protein receptor kinase | 
| Answer» C. Protein kinase C | |
| 8. | cAMP and cGMP are derived from ____________ | 
| A. | ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively | 
| B. | ATP and GTP by the actions of adenylate cyclase and gualnlate cyclase respectively | 
| C. | GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively | 
| D. | None of the mentioned | 
| Answer» C. GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively | |
| 9. | SH2 domain specifically binds to _____________ | 
| A. | GDP | 
| B. | Ca+2 | 
| C. | Phosphorylated tyrosine residues | 
| D. | Phosphorylated serine residues | 
| Answer» D. Phosphorylated serine residues | |
| 10. | WHICH_OF_THE_FOLLOWING_IS_A_SHORT-LIVED_MESSENGER_THAT_ACTS_BY_STIMULATING_A_SOLUBLE_GUANYLYL_CYCLASE,_RAISING_[CGMP]_AND_STIMULATING_PKG??$ | 
| A. | NO | 
| B. | NO<sub>2</sub> | 
| C. | NO<sub>3</sub><sup>–</sup> | 
| D. | N<sub>2</sub>O | 
| Answer» B. NO<sub>2</sub> | |
| 11. | Ras protein is a$ | 
| A. | G-protein switch | 
| B. | Small monomeric GTPase switch protein | 
| C. | Serine-threonine kinase | 
| D. | Tyrosine kinase | 
| Answer» C. Serine-threonine kinase | |
| 12. | cGMP-dependent protein kinase is also called | 
| A. | Protein kinase B | 
| B. | Protein kinase A | 
| C. | Protein kinase G | 
| D. | Protein kinase C | 
| Answer» D. Protein kinase C | |
| 13. | Activation of guanylyl cyclase produces | 
| A. | Guanosine 3’, 5’-cyclic monophosphate | 
| B. | Guanosine 2’, 5’-cyclic monophosphate | 
| C. | Guanosine 4’, 5’-cyclic monophosphate | 
| D. | Guanosine 1’, 5’-cyclic monophosphate | 
| Answer» B. Guanosine 2‚Äö√Ñ√∂‚àö√ë‚àö¬•, 5‚Äö√Ñ√∂‚àö√ë‚àö¬•-cyclic monophosphate | |
| 14. | Protein kinase ERK is activated by phosphorylation of | 
| A. | Only Thr | 
| B. | Only Tyr | 
| C. | Both Thr and Tyr | 
| D. | Only Ser | 
| Answer» D. Only Ser | |
| 15. | The enzyme activated by cyclic AMP, passing on the hormonal signal is | 
| A. | Protein kinase B | 
| B. | Protein kinase A | 
| C. | Protein kinase C | 
| D. | G protein receptor kinase | 
| Answer» C. Protein kinase C | |
| 16. | Which of the following is false about phosphorylation by IRS on serine residue? | 
| A. | It is an inhibitory phosphorylation | 
| B. | It is molecular mechanism for insulin resistance | 
| C. | It increases insulin levels | 
| D. | Target tissues fail to respond to circulating insulin | 
| Answer» D. Target tissues fail to respond to circulating insulin | |
| 17. | cAMP and cGMP are derived from | 
| A. | ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively | 
| B. | ATP and GTP by the actions of adenylate cyclase and gualnlate cyclase respectively | 
| C. | GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively | 
| D. | None | 
| Answer» C. GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively | |
| 18. | SH2 domain specifically binds to | 
| A. | GDP | 
| B. | Ca<sup>+2</sup> | 
| C. | Phosphorylated tyrosine residues | 
| D. | Phosphorylated serine residues | 
| Answer» D. Phosphorylated serine residues | |