 
			 
			MCQOPTIONS
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				This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Which of the following is true about ribonucease? | 
| A. | Native state which is catalytically inactive is denatured | 
| B. | Unfolded state is inactive | 
| C. | Renatured ribonuclease is inactive | 
| D. | Renaturation involves reestablishment of the correct disulfide cross links | 
| Answer» B. Unfolded state is inactive | |
| 2. | Protein A will fold into its native state only when protein B is also present in the solution. However, protein B can fold itself into native confirmation without the presence of protein A. Which of the following is true? | 
| A. | Protein B serves as precursor for protein A | 
| B. | Protein B serves as molecular chaperon for protein A | 
| C. | Protein B serves as ligand for protein A | 
| D. | Protein B serves as structural motif for protein A | 
| Answer» C. Protein B serves as ligand for protein A | |
| 3. | Process of folding does not depend on ____________ | 
| A. | Concentration of salts | 
| B. | pH | 
| C. | Solute | 
| D. | Solvent | 
| Answer» D. Solvent | |
| 4. | A process by which a protein structure assumes its functional shape or conformation is? | 
| A. | Denaturing | 
| B. | Folding | 
| C. | Synthesis | 
| D. | Hydrolysis | 
| Answer» C. Synthesis | |
| 5. | WHICH_OF_THE_FOLLOWING_IS_TRUE_ABOUT_RIBONUCEASE??$ | 
| A. | Native state which is catalytically inactive is denatured | 
| B. | Unfolded state is inactive | 
| C. | Renatured ribonuclease is inactive | 
| D. | Renaturation involves reestablishment of the correct disulfide cross links | 
| Answer» B. Unfolded state is inactive | |
| 6. | PROTEIN_A_WILL_FOLD_INTO_ITS_NATIVE_STATE_ONLY_WHEN_PROTEIN_B_IS_ALSO_PRESENT_IN_THE_SOLUTION._HOWEVER_PROTEIN_B_CAN_FOLD_ITSELF_INTO_NATIVE_CONFIRMATION_WITHOUT_THE_PRESENCE_OF_PROTEIN_A._WHICH_OF_THE_FOLLOWING_IS_TRUE??$ | 
| A. | Protein B serves as precursor for protein A | 
| B. | Protein B serves as molecular chaperon for protein A | 
| C. | Protein B serves as ligand for protein A | 
| D. | Protein B serves as structural motif for protein A | 
| Answer» C. Protein B serves as ligand for protein A | |
| 7. | Which of the following about spontaneous folding is false? | 
| A. | It involves initial formation of highly compact structure | 
| B. | It involves initial formation of a local secondary structure | 
| C. | It is essentially a random process | 
| D. | It may be defective in some human diseases | 
| Answer» D. It may be defective in some human diseases | |
| 8. | Which of the following are chaperons in E.coli? | 
| A. | Hsp70 | 
| B. | Hsp40 | 
| C. | DnaA | 
| D. | DnaK and DnaJ | 
| Answer» E. | |
| 9. | As folding progresses which of the following does not take place? | 
| A. | Entropy decreases | 
| B. | Amount of protein in native state increases | 
| C. | Free energy increases | 
| D. | Amount of protein in native state decreases | 
| Answer» E. | |
| 10. | Which of the following is a function of chaperone protein? | 
| A. | It degrades proteins that have folded improperly | 
| B. | It provide a template for how the proteins should fold | 
| C. | It rescues proteins that have folded improperly and allows them to refold properly | 
| D. | It degrades proteins that have folded properly | 
| Answer» D. It degrades proteins that have folded properly | |
| 11. | Which of the following cannot denature a protein? | 
| A. | Iodoacetic acid | 
| B. | SDS detergent | 
| C. | Urea | 
| D. | Heating to 90°C | 
| Answer» B. SDS detergent | |
| 12. | Process of folding does not depend on | 
| A. | Concentration of salts | 
| B. | pH | 
| C. | Solute | 
| D. | Solvent | 
| Answer» D. Solvent | |
| 13. | A process by which a protein structure assumes its functional shape or conformation is | 
| A. | Denaturing | 
| B. | Folding | 
| C. | Synthesis | 
| D. | Hydrolysis | 
| Answer» C. Synthesis | |
| 14. | Which of the following forces is favorable for protein folding? | 
| A. | Hydrophobic interactions | 
| B. | Hydrogen bonding | 
| C. | Vander Waals forces | 
| D. | Ionic bonding | 
| Answer» B. Hydrogen bonding | |