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This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The inactivation of M-Cdk is through the Cdc20-APC activity, what activates Cdc-20-APC? |
| A. | G1-Cdk |
| B. | G1-S-Cdk |
| C. | S-Cdk |
| D. | M-Cdk |
| Answer» E. | |
| 2. |
P53 requires ________________for its activity. |
| A. | Mdm |
| B. | MCM |
| C. | Securin |
| D. | Cdt |
| Answer» B. MCM | |
| 3. |
We know that caffeine helps to overcome M-Cdk activation checkpoint. What will be the fate of the cell treated with hydroxyl urea and caffeine in G1 phase? |
| A. | Cell will not divide |
| B. | Cell will become smaller in size |
| C. | Cell will divide with improper chromosome number |
| D. | Cell will undergo lysis |
| Answer» D. Cell will undergo lysis | |
| 4. |
WE_KNOW_THAT_CAFFEINE_HELPS_TO_OVERCOME_M-CDK_ACTIVATION_CHECKPOINT._WHAT_WILL_BE_THE_FATE_OF_THE_CELL_TREATED_WITH_HYDROXYL_UREA_AND_CAFFEINE_IN_G1_PHASE??$ |
| A. | Cell will not divide |
| B. | Cell will become smaller in size |
| C. | Cell will divide with improper chromosome number |
| D. | Cell will undergo lysis |
| Answer» D. Cell will undergo lysis | |
| 5. |
The inactivation of M-Cdk is through the Cdc20-APC activity, what activates Cdc-20-APC?$ |
| A. | G1-Cdk |
| B. | G1-S-Cdk |
| C. | S-Cdk |
| D. | M-Cdk |
| Answer» E. | |
| 6. |
P53 requires ________________for its activity.$ |
| A. | Mdm |
| B. | MCM |
| C. | Securin |
| D. | Cdt |
| Answer» B. MCM | |
| 7. |
What is a negative regulator of Cdc-20? |
| A. | M-Cdk |
| B. | Mad-2 |
| C. | Mdm |
| D. | Hct1 |
| Answer» C. Mdm | |
| 8. |
Which of the following is an activation process? |
| A. | Wee1 kinase |
| B. | APC |
| C. | Cdc25 |
| D. | p27 binding |
| Answer» D. p27 binding | |
| 9. |
The concentration of which of the following varies during the cell cycle? |
| A. | Cdk |
| B. | Cyclin |
| C. | SCF |
| D. | Proteosome |
| Answer» C. SCF | |
| 10. |
Which of the following true about Rb in the cell cycle? |
| A. | Phosphorylation of Rb will lead to its inactivation |
| B. | Phosphorylation of Rb will also lead to inactivation of E2F |
| C. | Phosphorylation of E2F will promote cell cycle progression |
| D. | E2F is directly affected by Rb |
| Answer» C. Phosphorylation of E2F will promote cell cycle progression | |
| 11. |
In an experiment you increase the concentration of Cln3. What will be its effect on proliferating yeast cells? |
| A. | Cells will be smaller in size |
| B. | Cells will still have normal size |
| C. | Cells will increase in size |
| D. | Cells will die off |
| Answer» B. Cells will still have normal size | |
| 12. |
Which of the following will prevent cell cycle from progressing in case of DNA damage? |
| A. | P53 |
| B. | G1 cyclin |
| C. | P10 |
| D. | Bcl-2 |
| Answer» B. G1 cyclin | |
| 13. |
Eggs in female stay in ______________ phase for extended duration. |
| A. | S |
| B. | G1 |
| C. | G2 |
| D. | M |
| Answer» E. | |
| 14. |
The cells before permanently differentiating enters into ______________ phase. |
| A. | G1 |
| B. | G2 |
| C. | G0 |
| D. | S |
| Answer» D. S | |
| 15. |
In cells the DNA replication takes place in _____________ phase. |
| A. | G0 |
| B. | G1 |
| C. | S |
| D. | G2 |
| Answer» D. G2 | |