MCQOPTIONS
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MCQOPTIONS
This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Biotechnology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
In the given picture, the marking “b” represents the drug concentration of which compartment? |
| A. | The central compartment in a two compartment model |
| B. | The peripheral compartment in a two compartment model |
| C. | The central compartment in a one compartment model |
| D. | Drug concentration of the plasma |
| Answer» C. The central compartment in a one compartment model | |
| 2. |
In the given picture, the marking “a” represents the drug concentration of which compartment? |
| A. | The central compartment in a two compartment model |
| B. | A peripheral compartment in a two compartment model |
| C. | The central compartment in a one compartment model |
| D. | Drug concentration of the plasma |
| Answer» B. A peripheral compartment in a two compartment model | |
| 3. |
Which of the following is not a category of 2 compartment model? |
| A. | Two compartment model with elimination from the central compartment |
| B. | Two compartment model with elimination from the peripheral compartment |
| C. | Two compartment model with elimination from only plasma and blood |
| D. | Two compartment model with elimination from both the compartments |
| Answer» E. | |
| 4. |
Which organ comprises the peripheral compartment in a two compartment model? |
| A. | Liver |
| B. | Lungs |
| C. | Kidneys |
| D. | Muscles |
| Answer» E. | |
| 5. |
Which organs comprise the central compartment in a two compartment model? |
| A. | Muscles |
| B. | Skin |
| C. | Adipose |
| D. | Liver |
| Answer» E. | |
| 6. |
At which of the four marked points of the plasma drug concentration versus time graph, absorption rate = elimination rate? |
| A. | a |
| B. | b |
| C. | c |
| D. | d |
| Answer» B. b | |
| 7. |
What is the equation to find out hepatic clearance? |
| A. | Plasma drug concentration/rate of elimination by the kidney |
| B. | Rate of elimination by kidney/plasma drug concentration |
| C. | 1 / rate of elimination by the kidney |
| D. | 1 / plasma drug concentration |
| Answer» C. 1 / rate of elimination by the kidney | |
| 8. |
To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient? |
| A. | 1080 ml |
| B. | 1080 g |
| C. | 1080 mg |
| D. | 1g/ml |
| Answer» D. 1g/ml | |
| 9. |
The i.v. bolus dosage is 500mg and the plasma drug concentration is 0.8 mg/ml. What should be the volume of distribution? |
| A. | 625 mg/ml |
| B. | 625 l |
| C. | 625 ml |
| D. | 0.0016 mg/ml |
| Answer» D. 0.0016 mg/ml | |
| 10. |
What is the equation to find out the apparent volume of distribution? |
| A. | Amount of drug in the body/plasma drug concentration |
| B. | Plasma drug concentration/amount of drug in the body |
| C. | 1 / plasma drug concentration |
| D. | 1 / Amount of drug in the body |
| Answer» B. Plasma drug concentration/amount of drug in the body | |
| 11. |
What is meant by elimination half-life? |
| A. | Time take for half of the amount of drug to get completely eliminated from only the organs |
| B. | Time take for half of the amount of drug to get completely eliminated from only blood |
| C. | Time take for half of the amount of drug to get completely eliminated from only plasma |
| D. | Time take for half of the amount of drug to get completely eliminated from the body as well as plasma |
| Answer» E. | |
| 12. |
In the equation log C = log Co – KEt/2.303, what does Co stand for _______ |
| A. | Plasma drug concentration after 60 min of i.v. injection |
| B. | Plasma drug concentration after 15 min of i.v. injection |
| C. | Plasma drug concentration after 30 min of i.v. injection |
| D. | Plasma drug concentration immediately after i.v. injection |
| Answer» E. | |
| 13. |
How much time does an intravenously administered drug take to complete a complete circulation? |
| A. | 5-8 min |
| B. | 7-10 min |
| C. | 1-3 min |
| D. | 1 min |
| Answer» D. 1 min | |
| 14. |
What does the word “open” mean in the one compartment open model? |
| A. | The drug easily enters |
| B. | The drug readily mixes with the blood |
| C. | Unidirectional input and output |
| D. | Easy absorption |
| Answer» D. Easy absorption | |