MCQOPTIONS
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MCQOPTIONS
This section includes 16 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Aly/REF is attached to the mRNA_______________ |
| A. | During poly adenylation |
| B. | During G cap binding |
| C. | During splicing |
| D. | During editing |
| Answer» D. During editing | |
| 2. |
Which of the following will be exported via CRM1? |
| A. | mRNA |
| B. | tRNA |
| C. | 5SrRNA |
| D. | DNA |
| Answer» D. DNA | |
| 3. |
Which of these interactions are weak? |
| A. | Ran.GTP-exportin-cargo |
| B. | Ran.GTP-NTF2 |
| C. | Ran.GDP-importin |
| D. | Ran-GTP-importin |
| Answer» D. Ran-GTP-importin | |
| 4. |
Which of the following proteins will have a higher cytosolic concentration? |
| A. | RAN.GTP |
| B. | CMR1 |
| C. | TAP |
| D. | NTF2 |
| Answer» E. | |
| 5. |
WHICH_OF_THESE_INTERACTIONS_ARE_WEAK??$ |
| A. | Ran.GTP-exportin-cargo |
| B. | Ran.GTP-NTF2 |
| C. | Ran.GDP-importin |
| D. | Ran-GTP-importin |
| Answer» D. Ran-GTP-importin | |
| 6. |
WHICH_OF_THE_FOLLOWING_PROTEINS_WILL_HAVE_A_HIGHER_CYTOSOLIC_CONCENTRATION??$ |
| A. | RAN.GTP |
| B. | CMR1 |
| C. | TAP |
| D. | NTF2 |
| Answer» E. | |
| 7. |
Aly/REF is attached to the mRNA_______________$ |
| A. | During poly adenylation |
| B. | During G cap binding |
| C. | During splicing |
| D. | During editing |
| Answer» D. During editing | |
| 8. |
Which of the following will be exported via CRM1?$ |
| A. | mRNA |
| B. | tRNA |
| C. | 5SrRNA |
| D. | DNA |
| Answer» D. DNA | |
| 9. |
Which one of the following is wrong about TAP? |
| A. | TAP can interact with the FG repeats |
| B. | TAP directly passes the mRNA through the |
| C. | siRNA against TAP will result in cytosolic accumulation of proteins with NLS |
| D. | TAP directly interacts with Aly/REF |
| Answer» D. TAP directly interacts with Aly/REF | |
| 10. |
CRM1 is necessary for the export of mRNA. |
| A. | True |
| B. | False |
| Answer» C. | |
| 11. |
Nuclear export sequence is _______________ rich. |
| A. | Lysine |
| B. | Leucine |
| C. | FG |
| D. | RGD |
| Answer» C. FG | |
| 12. |
The interaction of importin with Ran.GTP _____________________ its affinity for NLS. |
| A. | Increases |
| B. | Decreases |
| C. | Remains same |
| D. | They never interact |
| Answer» C. Remains same | |
| 13. |
Choose the correct one seen in nuclear end of the NPC. |
| A. | Ran.GDP |
| B. | Importin |
| C. | Ran. GTP |
| D. | Exportin.Ran.GDP |
| Answer» D. Exportin.Ran.GDP | |
| 14. |
The central plug is a mesh of FG rich nucleoporins. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 15. |
The basket like structure of filaments in NPC has _________ filaments and is located in ____________ side of the nuclear membrane. |
| A. | 6, nuclear |
| B. | 8, nuclear |
| C. | 6, cytosolic |
| D. | 8, cytosolic |
| Answer» C. 6, cytosolic | |
| 16. |
The proteins that are imported have a _______________ |
| A. | NES |
| B. | NLS |
| C. | FG rich domain |
| D. | Have to be less than 45KDa |
| Answer» C. FG rich domain | |