 
			 
			MCQOPTIONS
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				This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Which of the following is not a downstream component? | 
| A. | Ras | 
| B. | MEK | 
| C. | ERK | 
| D. | PIP3 | 
| Answer» E. | |
| 2. | Which of the following is involved in proline rich motif binding? | 
| A. | SH2 | 
| B. | SH3 | 
| C. | PTB | 
| D. | PH | 
| Answer» C. PTB | |
| 3. | Scaffold protein in insulin signal transduction ___________ | 
| A. | KSR | 
| B. | IRS-1 | 
| C. | MEKK1 | 
| D. | AKAP | 
| Answer» C. MEKK1 | |
| 4. | PTB domains bind to ___________ | 
| A. | Phosphorylated tyrosine | 
| B. | Phosphoryated threonine | 
| C. | Phosphorylated serine | 
| D. | Phosphorylated cysteine | 
| Answer» B. Phosphoryated threonine | |
| 5. | The specificity of signaling pathways does not include ___________ | 
| A. | Migration of signal proteins into membrane rafts | 
| B. | Assembly of large multiprotein complexes | 
| C. | Phosphorylation of target proteins at Ser, Thr/Tyr residues | 
| D. | Flippase-catalyzed movement of phospholipids from the inner to the outer leaflet | 
| Answer» E. | |
| 6. | WHICH_OF_THE_FOLLOWING_IS_INVOLVED_IN_PROLINE_RICH_MOTIF_BINDING??$ | 
| A. | SH2 | 
| B. | SH3 | 
| C. | PTB | 
| D. | PH | 
| Answer» C. PTB | |
| 7. | Which_of_the_following_is_not_a_downstream_component?$ | 
| A. | Ras | 
| B. | MEK | 
| C. | ERK | 
| D. | PIP3 | 
| Answer» E. | |
| 8. | Which of the following is involved in phospho-tyrosine binding? | 
| A. | SH2 | 
| B. | SH3 | 
| C. | PTB | 
| D. | PH | 
| Answer» B. SH3 | |
| 9. | Which of the following are stimulated to become membrane associated upon binding of insulin to the insulin receptor? | 
| A. | PH-domain | 
| B. | PTB | 
| C. | SH3 | 
| D. | SH2 | 
| Answer» B. PTB | |
| 10. | Which of the following converts GTP to cGMP to start its enzymatic cascade? | 
| A. | Receptor guanylyl cyclase | 
| B. | Receptor adenylyl cyclase | 
| C. | Calmodulin | 
| D. | Protein kinase-A | 
| Answer» B. Receptor adenylyl cyclase | |
| 11. | Which of the following is involved in extrinsic cell death pathway? | 
| A. | Heterotrimeric G protein complex | 
| B. | TRADD | 
| C. | IRS-1 | 
| D. | Protein-kinase A | 
| Answer» C. IRS-1 | |
| 12. | Scaffold protein in insulin signal transduction | 
| A. | KSR | 
| B. | IRS-1 | 
| C. | MEKK1 | 
| D. | AKAP | 
| Answer» C. MEKK1 | |
| 13. | PTB domains bind to | 
| A. | Phosphorylated tyrosine | 
| B. | Phosphoryated threonine | 
| C. | Phosphorylated serine | 
| D. | Phosphorylated cysteine | 
| Answer» B. Phosphoryated threonine | |
| 14. | Which of the following directly phosphorylate tyrosines to start a kinase protein enzymatic cascade? | 
| A. | Receptor tyrosine kinase | 
| B. | Receptor guanylyl cyclases | 
| C. | Receptor serine kinase | 
| D. | Receptor threonine kinase | 
| Answer» B. Receptor guanylyl cyclases | |
| 15. | The specificity of signaling pathways does not include | 
| A. | Migration of signal proteins into membrane rafts | 
| B. | Assembly of large multiprotein complexes | 
| C. | Phosphorylation of target proteins at Ser, Thr/Tyr residues | 
| D. | Flippase-catalyzed movement of phospholipids from the inner to the outer leaflet | 
| Answer» E. | |