

MCQOPTIONS
This section includes 21 Mcqs, each offering curated multiple-choice questions to sharpen your Biotechnology knowledge and support exam preparation. Choose a topic below to get started.
1. |
T cells are important in controlling |
A. | virus infections |
B. | allergy |
C. | autoimmunity |
D. | all of these |
Answer» E. | |
2. |
Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with |
A. | Ig MAbs |
B. | IgG |
C. | IgA |
D. | IgE |
Answer» B. IgG | |
3. |
The antigen-specific lymphocytes can be immortalized by which of the following method? |
A. | Transfection with tumor derived DNA |
B. | Hybridization with a suitable lymphoid tumor cell |
C. | Transformation following infection by Epstein-Barr virus (EB V) |
D. | All of the above |
Answer» E. | |
4. |
Which type of cell actually secrets antibodies? |
A. | plasma cells |
B. | T cells |
C. | macrophages |
D. | dendritic cells |
Answer» B. T cells | |
5. |
Helper T cells assist in the functions of |
A. | certain B cells |
B. | certain T cells |
C. | certain B cells and other T cells |
D. | none of the above |
Answer» D. none of the above | |
6. |
The EBV-hybridoma technique |
A. | immortalizes the donor Bcells |
B. | facilitates the proliferation of antigen specific B cells |
C. | gives much higher hybridization frequencies |
D. | all of the above |
Answer» E. | |
7. |
In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc., |
A. | T8 cells are greatly reduced |
B. | T8 cells are greatly increased |
C. | T4 cells are greatly reduced |
D. | T4 cells are greatly increased |
Answer» B. T8 cells are greatly increased | |
8. |
In human B cells and T cells are matured in the |
A. | bone marrow and thymus respectively |
B. | lymph nodes and spleen respectively |
C. | bursa and thymus respectively |
D. | none of these |
Answer» B. lymph nodes and spleen respectively | |
9. |
T cells are the source of |
A. | interleukin |
B. | interferon |
C. | lymphotoxin |
D. | all of these |
Answer» E. | |
10. |
The primary B cell receptor is |
A. | IgD |
B. | IgG |
C. | IgA |
D. | IgE |
Answer» B. IgG | |
11. |
It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at |
A. | high frequencies |
B. | moderate frequencies |
C. | low frequencies |
D. | at no frequency |
Answer» B. moderate frequencies | |
12. |
The hybrid cells can be propagated |
A. | in tissue culture |
B. | as ascites in peritoneal cavity of mice |
C. | both (a) and (b) |
D. | none of these |
Answer» D. none of these | |
13. |
TC cells are important in controlling |
A. | virus infections |
B. | allergy |
C. | autoimmunity |
D. | all of these |
Answer» E. | |
14. |
The cross linkage of antigens by antibodies is known as |
A. | agglutination |
B. | complement fixation |
C. | a cross reaction |
D. | all of these |
Answer» B. complement fixation | |
15. |
In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a |
A. | hybridoma |
B. | myeloma |
C. | natural killer cell |
D. | lymphoblast |
Answer» B. myeloma | |
16. |
The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as |
A. | transformation of antigen specific B lymphocytes (EBV) |
B. | hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes |
C. | combination of EB Vand hybridoma techniques |
D. | all of these |
Answer» E. | |
17. |
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the |
A. | absence of human immune response against murine proteins (HAMA) response |
B. | presence of HAMA response |
C. | poor recognition of immunoglobulin, Ig constant regions |
D. | all of the above |
Answer» B. presence of HAMA response | |
18. |
An example of mosaic antigen is |
A. | virus |
B. | bacteria |
C. | a hapten |
D. | protein |
Answer» B. bacteria | |
19. |
Small simple molecules are |
A. | poor antigens |
B. | rich antigens |
C. | moderate antigens |
D. | heterophilic antigens |
Answer» B. rich antigens | |
20. |
A cytokine that stimulates the activity of B and T cells is |
A. | lymphotoxin |
B. | interlukin-2 |
C. | interlukin-1 |
D. | all of these |
Answer» C. interlukin-1 | |
21. |
Which of the following is correct? |
A. | rabbits do not make myelomas whereas mice are unable to synthesize antibodies |
B. | rabbits do not make myelomas whereas mice are able to synthesize antibodies |
C. | rabbits make myelomas whereas mice are unable to synthesize antibodies |
D. | rabbits make myelomas whereas mice are able to synthesize antibodies |
Answer» B. rabbits do not make myelomas whereas mice are able to synthesize antibodies | |