Explore topic-wise MCQs in Biotechnology.

This section includes 21 Mcqs, each offering curated multiple-choice questions to sharpen your Biotechnology knowledge and support exam preparation. Choose a topic below to get started.

1.

T cells are important in controlling

A. virus infections
B. allergy
C. autoimmunity
D. all of these
Answer» E.
2.

Some cross reactions with monoclonal antibodies (MAbs) can occur. Unexpected cross reactions occur more frequently with

A. Ig MAbs
B. IgG
C. IgA
D. IgE
Answer» B. IgG
3.

The antigen-specific lymphocytes can be immortalized by which of the following method?

A. Transfection with tumor derived DNA
B. Hybridization with a suitable lymphoid tumor cell
C. Transformation following infection by Epstein-Barr virus (EB V)
D. All of the above
Answer» E.
4.

Which type of cell actually secrets antibodies?

A. plasma cells
B. T cells
C. macrophages
D. dendritic cells
Answer» B. T cells
5.

Helper T cells assist in the functions of

A. certain B cells
B. certain T cells
C. certain B cells and other T cells
D. none of the above
Answer» D. none of the above
6.

The EBV-hybridoma technique

A. immortalizes the donor Bcells
B. facilitates the proliferation of antigen specific B cells
C. gives much higher hybridization frequencies
D. all of the above
Answer» E.
7.

In immuno-inflammatory diseases such as hemolytic anaemia, eczema etc.,

A. T8 cells are greatly reduced
B. T8 cells are greatly increased
C. T4 cells are greatly reduced
D. T4 cells are greatly increased
Answer» B. T8 cells are greatly increased
8.

In human B cells and T cells are matured in the

A. bone marrow and thymus respectively
B. lymph nodes and spleen respectively
C. bursa and thymus respectively
D. none of these
Answer» B. lymph nodes and spleen respectively
9.

T cells are the source of

A. interleukin
B. interferon
C. lymphotoxin
D. all of these
Answer» E.
10.

The primary B cell receptor is

A. IgD
B. IgG
C. IgA
D. IgE
Answer» B. IgG
11.

It is highly valued if the lymphocytes derived from the lymph node or tonsil tend to undergo fusion at

A. high frequencies
B. moderate frequencies
C. low frequencies
D. at no frequency
Answer» B. moderate frequencies
12.

The hybrid cells can be propagated

A. in tissue culture
B. as ascites in peritoneal cavity of mice
C. both (a) and (b)
D. none of these
Answer» D. none of these
13.

TC cells are important in controlling

A. virus infections
B. allergy
C. autoimmunity
D. all of these
Answer» E.
14.

The cross linkage of antigens by antibodies is known as

A. agglutination
B. complement fixation
C. a cross reaction
D. all of these
Answer» B. complement fixation
15.

In monoclonal antibody technology, tumor cells that can replicate endlessly are fused with mammalian cells that produce an antibody. The result of this cell fusion is a

A. hybridoma
B. myeloma
C. natural killer cell
D. lymphoblast
Answer» B. myeloma
16.

The approach (s), which is/are currently followed to produce human monoclonal antibodies, is/are known as

A. transformation of antigen specific B lymphocytes (EBV)
B. hybridization of 6-thioguanine-resistant human plasmacytoma with immune human lymphocytes
C. combination of EB Vand hybridoma techniques
D. all of these
Answer» E.
17.

Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the

A. absence of human immune response against murine proteins (HAMA) response
B. presence of HAMA response
C. poor recognition of immunoglobulin, Ig constant regions
D. all of the above
Answer» B. presence of HAMA response
18.

An example of mosaic antigen is

A. virus
B. bacteria
C. a hapten
D. protein
Answer» B. bacteria
19.

Small simple molecules are

A. poor antigens
B. rich antigens
C. moderate antigens
D. heterophilic antigens
Answer» B. rich antigens
20.

A cytokine that stimulates the activity of B and T cells is

A. lymphotoxin
B. interlukin-2
C. interlukin-1
D. all of these
Answer» C. interlukin-1
21.

Which of the following is correct?

A. rabbits do not make myelomas whereas mice are unable to synthesize antibodies
B. rabbits do not make myelomas whereas mice are able to synthesize antibodies
C. rabbits make myelomas whereas mice are unable to synthesize antibodies
D. rabbits make myelomas whereas mice are able to synthesize antibodies
Answer» B. rabbits do not make myelomas whereas mice are able to synthesize antibodies