Explore topic-wise MCQs in Graduate Aptitude Test (GATE).

This section includes 92 Mcqs, each offering curated multiple-choice questions to sharpen your Graduate Aptitude Test (GATE) knowledge and support exam preparation. Choose a topic below to get started.

51.

If a segment of a sense strand of DNA is 5'-ATGGACCAGA-3', then the resulting RNA sequence after transcription is

A. 5-AGACCAGGTA-3
B. 5-UCUGGUCCAU-3
C. 5-UACCUGGUCU-3
D. 5-AUGGACCAGA-3
Answer» E.
52.

The repeat sequence of telomere in humans is

A. 5-TATAAT-3
B. 5-TTAGGG-3
C. 5-GGGCCC-3
D. 5-AAAAAA-3
Answer» C. 5-GGGCCC-3
53.

If serum is removed from the growth medium of human embryonic kidney cell line (HEK), then the cells will

A. proliferate faster
B. proliferate normally
C. undergo cell cycle arrest
D. undergo immediate apoptosis
Answer» D. undergo immediate apoptosis
54.

Consider an unfair coin. The probability of getting heads is 0.6. If you toss this coin twice, what is the probability that the first or the second toss is heads?

A. 0.56
B. 0.64
C. 0.84
D. 0.96
Answer» D. 0.96
55.

Which one of the following statements regarding G proteins is INCORRECT?

A. GDP is bound to G protein in the resting stage
B. GTP bound subunit cannot reassemble with dimer
C. All G proteins are trimeric
D. Activation of G protein may result in activation or inhibition of the target enzymes
Answer» D. Activation of G protein may result in activation or inhibition of the target enzymes
56.

Select the CORRECT combination of genetic components that are essential for the transfer of TDNA segment from Agrobacterium tumefaciens to plant cells.

A. Border repeat sequences and oncogenes
B. Border repeat sequences and vir genes
C. Opine biosynthetic genes and vir genes
D. Opine biosynthetic genes and oncogenes
Answer» C. Opine biosynthetic genes and vir genes
57.

In dead-end filtration, rate of filtration is

A. directly proportional to the square root of pressure drop across the filter medium
B. inversely proportional to the pressure drop across the filter medium
C. inversely proportional to the viscosity of the solution
D. inversely proportional to the square of viscosity of the solution
Answer» D. inversely proportional to the square of viscosity of the solution
58.

A biological process is involved in the ________ treatment of industrial effluent.

A. primary
B. secondary
C. tertiary
D. quaternary
Answer» C. tertiary
59.

Prandtl number is the ratio of

A. thermal diffusivity to momentum diffusivity
B. mass diffusivity to momentum diffusivity
C. momentum diffusivity to thermal diffusivity
D. thermal diffusivity to mass diffusivity
Answer» D. thermal diffusivity to mass diffusivity
60.

Based on their function, find the ODD one out.

A. miRNA
B. siRNA
C. shRNA
D. snRNA
Answer» E.
61.

Which one of the following statements is NOT true?

A. In competitive inhibition, substrate and inhibitor compete for the same active site of an enzyme
B. Addition of a large amount of substrate to an enzyme cannot overcome uncompetitive inhibition
C. A transition state analogue in enzyme catalyzed reaction increases the rate of product formation
D. In non-competitive inhibition, Km of an enzyme for its substrate remains constant as the concentration of the inhibitor increases
Answer» D. In non-competitive inhibition, Km of an enzyme for its substrate remains constant as the concentration of the inhibitor increases
62.

Which one of the following is NOT used for the measurement of cell viability in animal cell culture?

A. Trypan blue dye exclusion
B. Tetrazolium (MTT) assay
C. LDH activity in the culture medium
D. Coulter counter
Answer» E.
63.

Junctional diversity of antibody molecules results from

A. the addition of switch region nucleotides
B. the addition of N and P nucleotides
C. the joining of V, D and J segments
D. mutations in complementarity-determining regions
Answer» C. the joining of V, D and J segments
64.

Which one of the following is NOT an algorithm for building phylogenetic trees?

A. Maximum parsimony
B. Neighbor joining
C. Maximum likelihood
D. Bootstrap
Answer» E.
65.

ATP biosynthesis takes place utilizing the H+ gradient in mitochondria and chloroplasts. Identify the correct sites of H+ gradient formation.

A. Across the outer membrane of mitochondria and across the inner membrane of chloroplast
B. Across the inner membrane of mitochondria and across the thylakoid membrane of chloroplast
C. Within the matrix of mitochondria and across the inner membrane of chloroplast
D. Within the matrix of mitochondria and within the stroma of chloroplast
Answer» C. Within the matrix of mitochondria and across the inner membrane of chloroplast
66.

Which one of the following is NOT a therapeutic agent based on nucleic acid for the treatment of genetic disorders?

A. Antisense oligonucleotide
B. Ribozyme
C. Aptamer
D. Avidin
Answer» E.
67.

What will be the binding status of regulatory proteins in lac operon when concentrations of both lactose and glucose are very low in the culture medium?

A. Only the repressor remains bound to the operator
B. Only the cyclic AMP-Catabolic Activator Protein (cAMP-CAP) complex remains bound to the CAP binding site
C. Neither the repressor nor cAMP-CAP complex remain bound to their respective binding sites
D. Both the repressor and cAMP-CAP complex remain bound to their respective binding sites
Answer» E.
68.

Which family of viruses has single stranded DNA?

A. ) Herpesviridae
B. Poxviridae
C. Retroviridae
D. Parvoviridae
Answer» E.
69.

Bacteria with two or more flagella at one or both ends are called

A. amphitrichous
B. peritrichous
C. lophotrichous
D. atrichous
Answer» D. atrichous
70.

The binary operation □ is defined as a □ b = ab+(a+b), where a and b are any two real numbers. The value of the identity element of this operation, defined as the number x such that a □ x = a, for any a, is .

A. 0
B. 1
C. 2
D. 10
Answer» B. 1
71.

Find the missing sequence in the letter series. B, FH, LNP, _ _ _ _.

A. SUWY
B. TUVW
C. TVXZ
D. TWXZ
Answer» D. TWXZ
72.

Students taking an exam are divided into two groups, P and Q such that each group has the same number of students. The performance of each of the students in a test was evaluated out of 200 marks. It was observed that the mean of group P was 105, while that of group Q was 85. The standard deviation of group P was 25, while that of group Q was 5. Assuming that the marks were distributed on a normal distribution, which of the following statements will have the highest probability of being TRUE?

A. No student in group Q scored less marks than any student in group P.
B. No student in group P scored less marks than any student in group Q.
C. Most students of group Q scored marks in a narrower range than students in group P.
D. The median of the marks of group P is 100
Answer» D. The median of the marks of group P is 100
73.

A window is made up of a square portion and an equilateral triangle portion above it. The base of the triangular portion coincides with the upper side of the square. If the perimeter of the window is 6 m, the area of the window in m2 is ________

A. 1.43
B. 2.06
C. 2.68
D. 2.88
Answer» C. 2.68
74.

The unruly crowd demanded that the accused be _____________ without trial.

A. hanged
B. hanging
C. hankering
D. hung
Answer» B. hanging
75.

The volume of a sphere of diameter 1 unit is ________ than the volume of a cube of side 1 unit.

A. least
B. less
C. lesser
D. low
Answer» C. lesser
76.

The diameters of a large and a small vessel are 1.62 m and 16.2 cm, respectively. The vessels are geometrically similar and operated under similar volumetric agitated power input. The mixing time in the small vessel was found to be 15 s. Determine the mixing time (in seconds) in the large vessel

A. 15
B. 30
C. 61
D. 122
Answer» D. 122
77.

Choose the CORRECT sequence of steps involved in cytoplast production

A. Digestion of cell wall → protoplast viability → cybrid formation → osmotic stabilizer
B. Osmotic stabilizer → digestion of cell wall → protoplast viability → cybrid formation
C. Protoplast viability → osmotic stabilizer → digestion of cell wall → cybrid formation
D. Osmotic stabilizer → digestion of cell wall → cybrid formation → protoplast viability
Answer» C. Protoplast viability → osmotic stabilizer → digestion of cell wall → cybrid formation
78.

How many rooted and unrooted phylogenetic trees, respectively, are possible with four different sequences?

A. 3 and 15
B. 15 and 3
C. 15 and 12
D. 12 and 3
Answer» C. 15 and 12
79.

In DNA sequencing reactions using the chain termination method, the ratio of ddNTPs to dNTPs should be

A. 0
B. < 1
C. 1
D. > 1
Answer» C. 1
80.

How many 3-tuples are possible for the following amino acid sequence? MADCMWDISEASE

A. 4
B. 5
C. 11
D. 12
Answer» D. 12
81.

Which one of the following relations holds true for the specific growth rate (µ) of a microorganism in the death phase?

A. µ = 0
B. µ < 0
C. µ = µmax
D. 0 < µ < µmax
Answer» C. µ = µmax
82.

Which one of the following is INCORRECT about a typical apoptotic cell?

A. Phosphatidylserine is presented on the outer cell surface
B. Cytochrome c is released from mitochondria
C. Mitochondrial membrane potential does not change
D. Annexin-V binds to the cell surface
Answer» D. Annexin-V binds to the cell surface
83.

Production of monoclonal antibodies by hybridoma technology requires

A. splenocytes
B. osteocytes
C. hepatocytes
D. thymocytes
Answer» B. osteocytes
84.

Which one of the following features is NOT required in a prokaryotic expression vector?

A. oriC
B. Selection marker
C. CMV promoter
D. Ribosome binding site
Answer» D. Ribosome binding site
85.

Which one of the following amino acids has the highest probability to be found on the surface of a typical globular protein in aqueous environment?

A. Ala
B. Val
C. Arg
D. Ile
Answer» D. Ile
86.

Which one of the following organisms is used for the determination of phenol coefficient of a disinfectant?

A. Salmonella typhi
B. Escherichia coli
C. Candida albicans
D. Bacillus psychrophilus
Answer» B. Escherichia coli
87.

ABO blood group antigens in humans are differentiated from each other on the basis of

A. sialic acid
B. lipids
C. spectrin
D. glycoproteins
Answer» E.
88.

Anergy refers to

A. mitochondrial dysfunction
B. allergy to environmental antigens
C. unresponsiveness to antigens
D. a state of no energy
Answer» D. a state of no energy
89.

Based on the heavy chain, which one of the following antibodies has multiple subtypes?

A. IgM
B. IgD
C. IgE
D. IgG
Answer» E.
90.

Which one of the following is a second generation genetically engineered crop?

A. Bt brinjal
B. Roundup soyabean
C. Golden rice
D. Bt rice
Answer» D. Bt rice
91.

Levinthal’s paradox is related to

A. protein secretion
B. protein degradation
C. protein folding
D. protein trafficking
Answer» D. protein trafficking
92.

Which one of the following complement proteins is the initiator of the membrane attack complex?

A. C3a
B. C3b
C. C5a
D. C5b
Answer» E.