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This section includes 302 Mcqs, each offering curated multiple-choice questions to sharpen your Biology knowledge and support exam preparation. Choose a topic below to get started.
| 51. |
Segment of 'RNA' that have both negative and positive polarity regions is known as |
| A. | Neutral |
| B. | Dipolar |
| C. | Monopolar |
| D. | Ambisense |
| Answer» E. | |
| 52. |
The plasmid-mediated properties is/are |
| A. | fermentation of lactose |
| B. | production of enterotoxin |
| C. | resistance to antibiotics |
| D. | all of these |
| Answer» E. | |
| 53. |
The PCR/sequencing approach to rRNA is most likely to give information about |
| A. | the species to which the bacteria are most closely related |
| B. | morphology of the bacterium |
| C. | the type of energy metabolism the bacterium has |
| D. | whether the bacterium is motile |
| Answer» B. morphology of the bacterium | |
| 54. |
In which of the following uracil is present? |
| A. | RNA |
| B. | DNA |
| C. | Both (a) and (b) |
| D. | None of these |
| Answer» B. DNA | |
| 55. |
Changes in which of the following characterizes mutations? |
| A. | Phenotype |
| B. | Genotype |
| C. | Both (a) and (b) |
| D. | None of these |
| Answer» D. None of these | |
| 56. |
Which of the following component of RNA polymerase facilitates the recognition of promoter sequences? |
| A. | a subunit |
| B. | b subunit |
| C. | s subunit |
| D. | c subunit |
| Answer» D. c subunit | |
| 57. |
A sudden change in sequence of DNA or RNA, is called |
| A. | Change |
| B. | Alteration |
| C. | Mutation |
| D. | Transduction |
| Answer» D. Transduction | |
| 58. |
In lysogeny, |
| A. | a bacteriophage transfers bacterial DNA |
| B. | bacteria take up double stranded DNA from the environment |
| C. | DNA-degrading enzymes in the extracellular medium would stop the process |
| D. | a bacteriophage genome is integrated into the bacterial genome |
| Answer» E. | |
| 59. |
Which of the following is used by microbial genetisists as a tool? |
| A. | Bacteriophage |
| B. | Plasmids |
| C. | Transposable elements |
| D. | All of these |
| Answer» E. | |
| 60. |
Which of the following infection(s) can be diagnosed by the use of polymerase chain reaction? |
| A. | HIV-1 and HIV-2 viruses |
| B. | Hepatitis B virus |
| C. | Mycobacterium tuberculosis |
| D. | All of these |
| Answer» E. | |
| 61. |
According to base pairing rules the bases of one strand match-up with the bases of the second strand of DNA and the two strands are said to be |
| A. | complementary |
| B. | oppositely charged |
| C. | identical |
| D. | none of these |
| Answer» B. oppositely charged | |
| 62. |
If a base replaces by another base pair, sequence mutation, resulting replacement is known as |
| A. | Alternation |
| B. | Substitution |
| C. | Missense |
| D. | Nonsense |
| Answer» C. Missense | |
| 63. |
Process by which virus transfer gene from one cell to another, called as |
| A. | Replication |
| B. | Transfer |
| C. | Translation |
| D. | Transduction |
| Answer» E. | |
| 64. |
During 'conjugation' process of mating is controlled by |
| A. | F plasmid |
| B. | Fertility plasmid |
| C. | F factored |
| D. | All of above |
| Answer» E. | |
| 65. |
Integration of viral 'DNA' into cell 'DNA' results in a structure named as |
| A. | Viral genome |
| B. | Prophage |
| C. | Virion |
| D. | Prion |
| Answer» C. Virion | |
| 66. |
When exchange of segment between viruses having segmented genome, process is known as |
| A. | Recombination |
| B. | Transfer |
| C. | Translation |
| D. | Reassortment |
| Answer» E. | |
| 67. |
During amino acid activation a(n) |
| A. | amino acid is bound to tRNA |
| B. | amino acid is bound to mRNA |
| C. | methyl group is attached to rRNA |
| D. | methyl group is attached to an amino acid |
| Answer» B. amino acid is bound to mRNA | |
| 68. |
When mutations involve vital functions so that the mutants are nonviable, it is a |
| A. | nonsense mutation |
| B. | lethal mutation |
| C. | transversion |
| D. | none of these |
| Answer» C. transversion | |
| 69. |
The whole-genome shotgun sequencing approach depends primarily on |
| A. | rapidly sequencing thousands of small randomly cloned fragments |
| B. | methodical sequencing a few large cloned fragments of DNA |
| C. | sequencing the bacterial chromosome while it is still intact |
| D. | all of the above |
| Answer» B. methodical sequencing a few large cloned fragments of DNA | |
| 70. |
RNA that is complementary to a segment of another RNA molecule to which it will bind is known as |
| A. | missense RNA |
| B. | antisense RNA |
| C. | nonsense RNA |
| D. | none of these |
| Answer» C. nonsense RNA | |
| 71. |
F factor plasmids play a major role in |
| A. | conjugation |
| B. | replication |
| C. | transduction |
| D. | trasnscription |
| Answer» B. replication | |
| 72. |
What is the usual sequence of a Pribnow box? |
| A. | AUAUA |
| B. | TATAAT |
| C. | UUUUU |
| D. | TTGACA |
| Answer» C. UUUUU | |
| 73. |
Which of these catalyzes the synthesis of RNA from a DNA template? |
| A. | DNA gyrase |
| B. | DNA ligase |
| C. | DNA polymerase |
| D. | RNA polymerase |
| Answer» E. | |
| 74. |
Which of the termination codon is called amber? |
| A. | UAA |
| B. | UAG |
| C. | UGA |
| D. | AUG |
| Answer» C. UGA | |
| 75. |
Process, viruses or viral vectors, in combination with foreign viral envelope, producing proteins, known as |
| A. | Genotyping |
| B. | Pseudotyping |
| C. | Phenotyping |
| D. | Exchange |
| Answer» C. Phenotyping | |
| 76. |
Recombination of virus genomes occurs |
| A. | by transduction |
| B. | by transription |
| C. | simultaneous infection of a host cell by two viruses with homologous chromosomes |
| D. | by transformation |
| Answer» D. by transformation | |
| 77. |
Mutations that are valuable in determining function of viral 'gene' is called |
| A. | Substitution |
| B. | Frameshift mutation |
| C. | Conditional lethal mutation |
| D. | Point mutation |
| Answer» D. Point mutation | |
| 78. |
The correct term for the transfer of genetic material between bacteria in direct physical contact is |
| A. | conjugation |
| B. | transformation |
| C. | replication |
| D. | transduction |
| Answer» B. transformation | |
| 79. |
Which of the following statement can describe horizontal transfer? |
| A. | The synthesis of protein in RNA |
| B. | The transmission of genetic information from one independent, mature organism to another |
| C. | The transmission of genetic information from parent to offspring |
| D. | The synthesis of RNA from a DNA template |
| Answer» C. The transmission of genetic information from parent to offspring | |
| 80. |
What are approximate numbers of base pairs bacterial DNA ? |
| A. | 5 x 10^10 |
| B. | 5 x 10^6 |
| C. | 5 x 10^8 |
| D. | 5 x 10^11 |
| Answer» C. 5 x 10^8 | |
| 81. |
During process of complementation, helping virus mediate replication, in the |
| A. | Prion |
| B. | Virion |
| C. | Viroid |
| D. | Defective virus |
| Answer» E. | |
| 82. |
The components found in all prokaryotic transcription terminators is |
| A. | a poly-U region |
| B. | Rho factor |
| C. | a hairpin structure |
| D. | none of these |
| Answer» D. none of these | |
| 83. |
A wall less mycoplasma, having molecular weight, approximately |
| A. | 5 x 10^6 |
| B. | 5 x 10^10 |
| C. | 5 x 10^11 |
| D. | 5 x 10^8 |
| Answer» E. | |
| 84. |
The main difference between a self-transmissible and a mobilizable plasmid is that the self-transmissible plasmid |
| A. | transfers both strands of the plasmid DNA |
| B. | carries genes encoding the mating apparatus |
| C. | transfers antibiotic resistance genes |
| D. | usually has a transposon inserted into it |
| Answer» C. transfers antibiotic resistance genes | |
| 85. |
Thymine dimers are directly repaired with the help of visible light by process known as |
| A. | phosphorylation |
| B. | excision repair |
| C. | photosynthesis |
| D. | photoreactivation |
| Answer» E. | |
| 86. |
Which of the following genetic elements carry the genes required for integration into host chromosomes? |
| A. | Replicon |
| B. | Plasmids |
| C. | Transposons |
| D. | Tandons |
| Answer» D. Tandons | |
| 87. |
Example of single-stranded 'RNA' virus with negative polarity is |
| A. | Myxovirus |
| B. | Parvoviruses |
| C. | Poxvirus |
| D. | Poliovirus |
| Answer» B. Parvoviruses | |
| 88. |
The nonsense codon(s) is/are |
| A. | UAG |
| B. | UAA |
| C. | UGA |
| D. | all of these |
| Answer» E. | |
| 89. |
Recipient bacteria in conjugation are usually |
| A. | Female bacterium |
| B. | Male bacterium |
| C. | Bacterium |
| D. | E.Coli |
| Answer» B. Male bacterium | |
| 90. |
Plasmid that carries genes encoding enzymes, which degrade substances such as aromatic compounds, pesticides or sugar are |
| A. | F factors |
| B. | metabolic plasmid |
| C. | virulence plasmid |
| D. | none of these |
| Answer» C. virulence plasmid | |
| 91. |
Which type of plasmid can exist with or without being integrated into the host's chromosome? |
| A. | Medisome |
| B. | Lisosome |
| C. | Lysogen |
| D. | Episome |
| Answer» E. | |
| 92. |
First step of 'viral replication' cycle is |
| A. | Attachment |
| B. | Penetration |
| C. | Uncoating of viral genome |
| D. | Doubling |
| Answer» B. Penetration | |
| 93. |
The location of first hexameric sequence typically found in pro-karyotic promoters is |
| A. | at the transcription start site |
| B. | approximately 35 bases upstream of the transcription start site |
| C. | approximately 10 bases upstream of the transcription start site |
| D. | approximately 25 bases upstream of the transcription start site |
| Answer» C. approximately 10 bases upstream of the transcription start site | |
| 94. |
RNA populations can also be used as PCR templates after reverse transcription into |
| A. | c DNA |
| B. | t RNA |
| C. | m DNA |
| D. | r RNA |
| Answer» B. t RNA | |
| 95. |
Poliovirus have single-stranded 'RNA' of |
| A. | Negative polarity |
| B. | Positive polarity |
| C. | Neutral |
| D. | Bipolar |
| Answer» C. Neutral | |
| 96. |
Which of the following proteins first binds to TATA box during transcription? |
| A. | TF II A |
| B. | TF II D |
| C. | TF II B |
| D. | RNA polymerase |
| Answer» C. TF II B | |
| 97. |
The type of recombination that commonly occurs between a pair of homologous DNA sequences is, |
| A. | mutagenic recombination |
| B. | site-specific recombination |
| C. | replicative recombination |
| D. | general recombination |
| Answer» E. | |
| 98. |
After completion of a viral replication cycle number of progeny in host cell is, approximately |
| A. | 100 virion |
| B. | 200 virion |
| C. | 50 virion |
| D. | 40 virion |
| Answer» B. 200 virion | |
| 99. |
Which 'DNA' does not have a double strand DNA ? |
| A. | Poxviruses |
| B. | Parvoviruses |
| C. | HIV |
| D. | HCV |
| Answer» C. HIV | |
| 100. |
Process, one or both viruses infect cells, having mutation and produced nonfictional protein, called as |
| A. | Recombination |
| B. | Reassortment |
| C. | Complementation |
| D. | Transduction |
| Answer» D. Transduction | |