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This section includes 302 Mcqs, each offering curated multiple-choice questions to sharpen your Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Assertion (A) : DNA finger printing has became a powerful tool to establish paternity and identity of criminal in rape and assault cases.Reason (R) : Trace evidences such as hair, saliva and dried semen are adequate for DNA analysis.Codes |
| A. | Bot A and B are true and R is the correct explanation of A. |
| B. | Both A and R are true but R is not the correct explanation of A. |
| C. | A is true but R is false. |
| D. | A is false but R is true. |
| Answer» B. Both A and R are true but R is not the correct explanation of A. | |
| 2. |
Assertion (A) : Insect resistance transgenic cotton has been produced by inserting Bt gene.Reason (R) : The Bt gene is derived from a bacterium.Code |
| A. | Both A and R are true and R is the Correct explanation of A. |
| B. | Both A and R are true but R is not the correct explanation of A. |
| C. | A is true but R is false. |
| D. | A is false but R is true. |
| Answer» C. A is true but R is false. | |
| 3. |
Assertion (A) : In human being the female play a major role in determining the sex of the offspring. Reason (R) : Women have two X - chromosomes.Codes |
| A. | Both A and Rare true and R is the correct explanation of A. |
| B. | Both A and R are true but R is not a correct explanation of A. |
| C. | A is true but R is false. |
| D. | A is false but R is true. |
| Answer» E. | |
| 4. |
Assertion (A) : Dolly was the first cloned mammal.Reason (R) : Dolly was produced by invitro fertilization. |
| A. | Both A and R are true and R is correct explanation of A. |
| B. | Both A and R are true but R is not the correct explanation of A. |
| C. | A is true but R is false. |
| D. | A is false but R is true. |
| Answer» E. | |
| 5. |
Mendel's law apply only when |
| A. | Characters are linked |
| B. | Parents are pure breeing |
| C. | F |
| D. | monohybrid ratio shows two type of individuals |
| E. | First pair of contrasting characters is dependent upon other pairs |
| Answer» C. F | |
| 6. |
Which of the following professional are more likely to run the risk of a permanent change in their cell's DNA ?1. Rescarchers using carbon 14 isotope2. X - ray technicia3. Cola miner4. Dyer and painterCode |
| A. | 2 alone |
| B. | 1, 2 and 3 |
| C. | 1, 2 and 4 |
| D. | 1, 3 and 4 |
| Answer» D. 1, 3 and 4 | |
| 7. |
Which one of the following statements is correct ?Cretinism is human disorder which is due to the under secretion of |
| A. | Adrenalin harmone |
| B. | Cortisone harmone |
| C. | Glucagon harmone |
| D. | Thyroxin harmone |
| Answer» E. | |
| 8. |
In the context of genetic disorders, consider the followingA women suffer from colour blindness while her husband does not suffer from it. They have a son and a daughter. In this context, which one of the following statements is most probably correct ? |
| A. | Both children suffer from colour blindness |
| B. | Daughter suffer from colour blindness while son does not suffer from it |
| C. | Both children do not suffer from colour blindness |
| D. | Son suffers from colour blindness while daughter does not suffer from it. |
| Answer» E. | |
| 9. |
Mendel's law of independent assortment is based on F2 ratio of |
| A. | 1 : 2 : 1 |
| B. | 9 : 3 : 3 : 1 |
| C. | 2 : 1 |
| D. | 3 : 1 |
| Answer» C. 2 : 1 | |
| 10. |
Match List_I with List_II and select the correct answer using the codes given below:List-IList-IIF. Theory of mutation1.Beadle and TatumG. Theory of evolution2.Jacob and MonodH. One gene one enzyme hypothesis3.DarwinJ. Operon concept4.De VriesCodesFGHJA.3412B.4312C.4312D.3421 |
| A. | A. |
| B. | B. |
| C. | C. |
| D. | D. |
| Answer» C. C. | |
| 11. |
Stem and loop structures are |
| A. | proteins that help partially denatured enzymes to recover their native configuration |
| B. | structures in DNA caused by inverted repeats |
| C. | structures at the ends of linear eukaryotic DNA molecules |
| D. | the bonds between adjacent DNA nucleotides in the same strand |
| Answer» C. structures at the ends of linear eukaryotic DNA molecules | |
| 12. |
An mRNA transcript of a gene contains |
| A. | a start codon |
| B. | a stop codon |
| C. | a terminator |
| D. | all of these |
| Answer» E. | |
| 13. |
Enzymes?reverse 'transcriptase' is coded by |
| A. | Gag gene |
| B. | Pol gene |
| C. | Tat gene |
| D. | Vif gene |
| Answer» C. Tat gene | |
| 14. |
Differentiation of four different bases in automated sequencing systems is that each base has |
| A. | different radioactive tag |
| B. | cytosine at start |
| C. | unique antibody bound to it |
| D. | distinctive fluorescent tag |
| Answer» E. | |
| 15. |
A specific __________ factor helps RNA polymerase bind to late promoters and transcribe late genes. |
| A. | sigma |
| B. | beta |
| C. | delta |
| D. | gamma |
| Answer» B. beta | |
| 16. |
Which of the following type of recombination does not require homologous sequences and is important for the integration of viral genomes into bacterial chromosomes? |
| A. | Mutagenic recombimation |
| B. | Site-specific recombination |
| C. | Replicative recombination |
| D. | General recombination |
| Answer» C. Replicative recombination | |
| 17. |
Between two chromosomes exchange of 'gene' is called as |
| A. | Interaction |
| B. | Mutation |
| C. | Recombination |
| D. | Point mutation |
| Answer» D. Point mutation | |
| 18. |
Which of the following transport bacterial DNA to other bacteria via bacteriophages? |
| A. | Conjugation |
| B. | Transduction |
| C. | Transformation |
| D. | Translation |
| Answer» C. Transformation | |
| 19. |
The DNA sequences of rRNA genes can be used to |
| A. | assess relatedness of eukaryotes but not prokaryotes |
| B. | obtain a tentative identification of a new microorganism |
| C. | predict the pulsed field gel pattern of a microorganism |
| D. | predict whether a bacteria will be gram-positive or gram-negative |
| Answer» C. predict the pulsed field gel pattern of a microorganism | |
| 20. |
R factors involved in plant-microbe interactions are |
| A. | plant proteins |
| B. | bacterial proteins |
| C. | essential for transfer of DNA to plant cells |
| D. | also called opines |
| Answer» B. bacterial proteins | |
| 21. |
The mutation which will not affect the length of a protein is, |
| A. | nonsense mutation |
| B. | missense mutation |
| C. | frameshift mutation |
| D. | all of these |
| Answer» C. frameshift mutation | |
| 22. |
Which of the following statement(s) is/are true in regards to F+ x F- mating events? |
| A. | DNA is transferred from F- to F+ cells |
| B. | DNA is transferred from F+ to F- cells |
| C. | No DNA is transferred because F- cells are unable to perform conjugation |
| D. | No DNA is transferred because F+ cells are unable to perform conjugation |
| Answer» C. No DNA is transferred because F- cells are unable to perform conjugation | |
| 23. |
Which of the following modified amino acid is used at the starting of most prokaryotic proteins? |
| A. | N-formylserine |
| B. | N-formylmethionine |
| C. | N-formylleucine |
| D. | N-formylalanine |
| Answer» C. N-formylleucine | |
| 24. |
A mutagen is defined as |
| A. | an enzyme that repairs mutations |
| B. | a chemical or physical agent that induces mutations |
| C. | an inhibitor of gene modification |
| D. | a molecule which stabilizes DNA thus prevents mutations from occurring |
| Answer» C. an inhibitor of gene modification | |
| 25. |
Substitutions that prematurely stops synthesis of protein, by generating stop codon, called as |
| A. | Missense mutation |
| B. | Nonsense mutation |
| C. | Frameshift mutation |
| D. | Alternation |
| Answer» B. Nonsense mutation | |
| 26. |
The cloning step in PCR/sequencing analysis of microbial communities is necessary for |
| A. | the amplification process |
| B. | preventing contamination by outside DNA |
| C. | separating the different rRNA gene sequences in the mixture |
| D. | none of these |
| Answer» D. none of these | |
| 27. |
Frame shift mutation may occur as a result of |
| A. | formation of a thymine-dimer |
| B. | deamination of cytosine to uracil |
| C. | conversion of guanine to xanthine |
| D. | none of the above |
| Answer» E. | |
| 28. |
Process of mating through which two bacterial cells transfer their DNA, a cell acts as a host while other as recipient, process is known as |
| A. | Transduction |
| B. | Transformation |
| C. | Conjugations |
| D. | Mating |
| Answer» D. Mating | |
| 29. |
Which of the following plamids do not possess information for self transfer to another cell? |
| A. | Cryptic plasmids |
| B. | Conjugative plasmids |
| C. | Non-conjugative plasmids |
| D. | None of these |
| Answer» D. None of these | |
| 30. |
The chromosomal genes, possessing fertility factor is known as |
| A. | R factor |
| B. | F prime factor |
| C. | HFr |
| D. | F factor |
| Answer» C. HFr | |
| 31. |
Which of the following is a product of transcription? |
| A. | mRNA |
| B. | tRNA |
| C. | rRNA |
| D. | all of these |
| Answer» E. | |
| 32. |
The efficiency of amplification in PCR in later cycles is reduced due to |
| A. | reduction in substrate concentration |
| B. | insufficient enzyme and time to synthesize mass quantity of DNA |
| C. | build up of PCR product which competes with primers for hybrid formation |
| D. | all of these |
| Answer» E. | |
| 33. |
A nonsense mutation introduced into the DNA sequence of a gene may |
| A. | cause premature termination of the mRNA |
| B. | shorten the length of the protein encoded by the gene |
| C. | have no effect on the transcript or protein made |
| D. | cause a shift in reading frame |
| Answer» C. have no effect on the transcript or protein made | |
| 34. |
The term used for acquisition of naked DNA from its environment and its incorporation in their genome by a bacterium is |
| A. | transformation |
| B. | lysogenic conversion |
| C. | conjugation |
| D. | transduction |
| Answer» B. lysogenic conversion | |
| 35. |
Recognition/binding site of RNA polymerase is called |
| A. | receptor |
| B. | promoter |
| C. | facilitator |
| D. | terminator |
| Answer» C. facilitator | |
| 36. |
Which of the following defines an open reading frame (ORF)? |
| A. | A sequence of genome in bacteriophage |
| B. | The sequence of a complete genome |
| C. | A plasmid vector used in genome sequencing |
| D. | A possible gene predicted by DNA sequencing |
| Answer» E. | |
| 37. |
Inability to replicate, in certain viruses, providing an ultimae advantage in the |
| A. | Gene therapy |
| B. | Drug therapy |
| C. | Physiotherapy |
| D. | Chemotherapy |
| Answer» B. Drug therapy | |
| 38. |
In viral 'gene' expression first step is synthesis of |
| A. | Messenger RNA |
| B. | Transfer RNA |
| C. | Ribosomal RNA |
| D. | Proteins |
| Answer» B. Transfer RNA | |
| 39. |
'Gag' and 'pol' are viral |
| A. | Function unit |
| B. | Nucleocapsid |
| C. | Structural proteins |
| D. | Subunits |
| Answer» D. Subunits | |
| 40. |
Inverted repeat sequences at each end and a gene encoding transposase is contained in which of the following transposable element? |
| A. | Composite transposon |
| B. | Insertion element |
| C. | Virus |
| D. | Plasmid |
| Answer» C. Virus | |
| 41. |
The plasmids can be eliminated from a cell by the process known as |
| A. | curing |
| B. | breaking |
| C. | fixing |
| D. | expulsion |
| Answer» B. breaking | |
| 42. |
Transfer of 'DNA' mediated by bacteriophage is called as |
| A. | Transduction |
| B. | Transformation |
| C. | Conjugations |
| D. | Mating |
| Answer» B. Transformation | |
| 43. |
Which of the following statement defines a replicon? |
| A. | A DNA molecule that encodes pili for conjugation |
| B. | A DNA molecule that is able to replicate and be maintained |
| C. | A DNA template which is used in transcription |
| D. | The enzyme responsible for transposition |
| Answer» C. A DNA template which is used in transcription | |
| 44. |
What is the term used for a segment of DNA with one or more genes in the centre and the two ends carrying inverted repeat sequences of nucleotides? |
| A. | Plasmid |
| B. | Transposon |
| C. | Insertion sequence |
| D. | None of these |
| Answer» C. Insertion sequence | |
| 45. |
Genetic material of bacteria is composed of, a single-stranded |
| A. | Linear DNA |
| B. | Ladder like DNA |
| C. | Coiled DNA |
| D. | Circular DNA |
| Answer» E. | |
| 46. |
In therapeutic process, nucleic acid is delivered in patient's cell as a drug to recover a disease, process is known as |
| A. | Drug therapy |
| B. | Physiotherapy |
| C. | Gene therapy |
| D. | Chemotherapy |
| Answer» D. Chemotherapy | |
| 47. |
The template for PCR is |
| A. | RNA |
| B. | single stranded DNA |
| C. | double stranded DNA |
| D. | none of these |
| Answer» D. none of these | |
| 48. |
Which of the following statement describes plasmids? |
| A. | Another name for a protoplast |
| B. | A complex membrane structure that covers the chromosome of bacteria |
| C. | Small, circular DNA molecules that can exist independently of chromosomes commonly found in bacteria |
| D. | None of the above |
| Answer» D. None of the above | |
| 49. |
The expression of gene X (which has promoter Px) is to be monitored. A gene fusion construction for carrying this work will |
| A. | have Px but not the rest of the X coding region |
| B. | have the promoter of lacZ or some other reporter gene |
| C. | allow to monitor the expression of all genes with a promoter similar in sequence to Px |
| D. | give the same information as from a microarray |
| Answer» B. have the promoter of lacZ or some other reporter gene | |
| 50. |
Which of the following type of recombination does not require homologous sequences and is utilized by mobile genetic elements that move about chromosomes? |
| A. | Mutagenic recombimation |
| B. | Site-specific recombination |
| C. | Replicative recombination |
| D. | General recombination |
| Answer» D. General recombination | |