MCQOPTIONS
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MCQOPTIONS
This section includes 45 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The sequence of one strand of DNA is: 5' ATTGCCA 3', what is the sequence of the other strand? |
| A. | 5' TAACGGT 3' |
| B. | 5' TGGCAAT 3' |
| C. | 5' ATTGCCA 3' |
| D. | 5' UAAGCCU3' |
| Answer» C. 5' ATTGCCA 3' | |
| 2. |
How many amino acids will be encoded by 5' GAU GGU UGA UGU 3' sequence? |
| A. | One |
| B. | Two |
| C. | Three |
| D. | Four |
| Answer» C. Three | |
| 3. |
The “standard” genetic code is almost universal? |
| A. | False |
| B. | True |
| Answer» C. | |
| 4. |
What are the codons that specify the same amino acid called? |
| A. | Stop codons |
| B. | Start codons |
| C. | Acronyms |
| D. | Synonyms |
| Answer» E. | |
| 5. |
Which of the following codons are known as non-sense codons? |
| A. | UGA only |
| B. | UAG only |
| C. | UAA only |
| D. | UGA, UAG, and UAA |
| Answer» E. | |
| 6. |
Which amino acid does AUG code for? |
| A. | Cysteine |
| B. | Valine |
| C. | Glycine |
| D. | Methionine |
| Answer» E. | |
| 7. |
Which of the following is the start codon? |
| A. | CUC |
| B. | ACC/CCA |
| C. | GUA |
| D. | AUG/GUG |
| Answer» E. | |
| 8. |
The genetic code has no punctuation to indicate the reading frame; instead, the nucleotide sequence is read sequentially, triplet by triplet? |
| A. | False |
| B. | True |
| Answer» C. | |
| 9. |
Which of the following mutation is known as frameshift mutation? |
| A. | All mutations |
| B. | Only the deletion of single nucleotide |
| C. | Only addition of a single nucleotide |
| D. | Both addition and deletion of single nucleotide |
| Answer» E. | |
| 10. |
Which of the following gives the correct characteristics of the genetic code? |
| A. | Duplet, overlapping, and degenerate |
| B. | Duplet, non-overlapping, and degenerate |
| C. | Triplet, overlapping, and degenerate |
| D. | Triplet, non-overlapping, degenerate |
| Answer» E. | |
| 11. |
The triplet code allows many amino acids to be specified by more than one codon. Such a code is said to be degenerate? |
| A. | False |
| B. | True |
| Answer» C. | |
| 12. |
If a codon contains four bases, then how many possible codons can be formed utilizing the four most commonly occurring bases? |
| A. | 16 |
| B. | 64 |
| C. | 704 |
| D. | 256 |
| Answer» E. | |
| 13. |
What is a codon? |
| A. | A single base necessary to specify a single amino acid |
| B. | A group of two bases necessary to specify a single amino acid |
| C. | A group of three bases necessary to specify a single amino acid |
| D. | A group of several bases necessary to specify a single amino acid. |
| Answer» E. | |
| 14. |
What is the genetic code? |
| A. | Code of enzymatic analysis of genes |
| B. | Code of genome sequencing |
| C. | The message stored in proteins for the synthesis of DNA |
| D. | The message stored in DNA for the synthesis of proteins |
| Answer» E. | |
| 15. |
Who proposed the central dogma? |
| A. | Louis Pasteur |
| B. | Gregor Mendel |
| C. | Francis Collins |
| D. | Francis Crick |
| Answer» E. | |
| 16. |
Which of the following is the correct sequence of central dogma? |
| A. | Protein → RNA → DNA |
| B. | RNA → protein → DNA |
| C. | DNA → protein → RNA |
| D. | DNA → RNA → protein |
| Answer» E. | |
| 17. |
If you charge a lys-tRNA with an alanine, what amino acid will you expect to be incorporated against AAA? |
| A. | Lysine |
| B. | Alanine |
| C. | Phenylalanine |
| D. | f-alanine |
| Answer» C. Phenylalanine | |
| 18. |
Which of these mutations will have the least harmful effect? |
| A. | Addition of 2 bases |
| B. | Deletion of 3 bases |
| C. | Transition of one base |
| D. | Deletion of a chunk |
| Answer» D. Deletion of a chunk | |
| 19. |
State whether it is true that degeneracy can act as a mode of control in RNA? |
| A. | True |
| B. | False |
| Answer» B. False | |
| 20. |
Which of the following codon calls for fMettRNA –fMet? |
| A. | CTA |
| B. | GUA |
| C. | AUG |
| D. | AUA |
| Answer» D. AUA | |
| 21. |
Wobble hypothesis was first proposed by ____________ |
| A. | Nirenberg |
| B. | Watson and Crick |
| C. | Watson |
| D. | Crick |
| Answer» E. | |
| 22. |
The genetic code translated the language of ____________ |
| A. | Proteins into that of RNA |
| B. | Amino acids into that of RNA |
| C. | RNA into that of proteins |
| D. | RNA into that of DNA |
| Answer» D. RNA into that of DNA | |
| 23. |
In which of the following cases the first base of anticodon pairs with three codons? |
| A. | When the first base of anticodon is A or C |
| B. | When the first base of anticodon is A or G |
| C. | When the first base of anticodon is inosine |
| D. | When the first base of anticodon is G or U |
| Answer» D. When the first base of anticodon is G or U | |
| 24. |
The termination codon is not ____________ |
| A. | AUG |
| B. | UAA |
| C. | UAG |
| D. | UGA |
| Answer» B. UAA | |
| 25. |
The initiation codon is ____________ |
| A. | AUG |
| B. | UAA |
| C. | UAG |
| D. | UGA |
| Answer» B. UAA | |
| 26. |
A codon contains how many nucleotides? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» D. 4 | |
| 27. |
WHICH_OF_THESE_MUTATIONS_WILL_HAVE_THE_LEAST_HARMFUL_EFFECT??$ |
| A. | Addition of 2 bases |
| B. | Deletion of 3 bases |
| C. | Transition of one base |
| D. | Deletion of a chunk |
| Answer» D. Deletion of a chunk | |
| 28. |
THE_GENETIC_CODE_TRANSLATED_THE_LANGUAGE_OF?$ |
| A. | Proteins into that of RNA |
| B. | Amino acids into that of RNA |
| C. | RNA into that of proteins |
| D. | RNA into that of DNA |
| Answer» D. RNA into that of DNA | |
| 29. |
STATE_WHETHER_IT_IS_TRUE_THAT_DEGENERACY_CAN_ACT_AS_A_MODE_OF_CONTROL_IN_RNA??$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 30. |
If you charge a lys-tRNA with an alanine, what amino acid will you expect to be incorporated against AAA?$ |
| A. | Lysine |
| B. | Alanine |
| C. | Phenylalanine |
| D. | f-alanine |
| Answer» C. Phenylalanine | |
| 31. |
Wobble_hypothesis_was_first_proposed_by$ |
| A. | Nirenberg |
| B. | Watson and Crick |
| C. | Watson |
| D. | Crick |
| Answer» E. | |
| 32. |
If you consider wooble hypothesis I in 1st position of anticodon can not pair with? |
| A. | A is 3<sup>rd</sup> position of codon |
| B. | U is 3<sup>rd</sup> position of codon |
| C. | G is 3<sup>rd</sup> position of codon |
| D. | C is 3<sup>rd</sup> position of codon |
| Answer» D. C is 3<sup>rd</sup> position of codon | |
| 33. |
In which of the following cases the first base of anticodon pairs with two codons? |
| A. | When the first base of anticodon is A or C |
| B. | When the first base of anticodon is A or G |
| C. | When the first base of anticodon is inosine |
| D. | When the first base of anticodon is G or U |
| Answer» E. | |
| 34. |
Wooble base hypothesis is applicable to the____________ |
| A. | Mitochondrial codon |
| B. | 1<sup>st</sup> base in codon |
| C. | 2<sup>nd</sup> base in codon |
| D. | 3<sup>rd</sup> base in codon |
| Answer» E. | |
| 35. |
In which of the following cases the first base of anticodon pairs with only one codon? |
| A. | When the first base of anticodon is A or C |
| B. | When the first base of anticodon is A or G |
| C. | When the first base of anticodon is inosine |
| D. | When the first base of anticodon is G or U |
| Answer» B. When the first base of anticodon is A or G | |
| 36. |
In an experiment if you add poly A oigon-dNTP in a nucleotide free cell lysate. Which of the labeled amino acid do you expect to be incorporated in the peptide so formed? |
| A. | Lys |
| B. | Phe |
| C. | Pro |
| D. | Leu |
| Answer» C. Pro | |
| 37. |
Which position of a codon is said to wobble? |
| A. | First |
| B. | Second |
| C. | Third |
| D. | Fourth |
| Answer» D. Fourth | |
| 38. |
Which of the following is not a stop codon? |
| A. | UAA |
| B. | GUG |
| C. | UAG |
| D. | UGA |
| Answer» C. UAG | |
| 39. |
How many t-RNAs are required to translate all 61 codons? |
| A. | 31 |
| B. | 32 |
| C. | 30 |
| D. | 29 |
| Answer» C. 30 | |
| 40. |
Consider that our codon in place of being triplet was quadruplet. How many possible combinations could be there then? |
| A. | 64 |
| B. | 128 |
| C. | 256 |
| D. | 360 |
| Answer» D. 360 | |
| 41. |
The termination codon is not |
| A. | AUG |
| B. | UAA |
| C. | UAG |
| D. | UGA |
| Answer» B. UAA | |
| 42. |
What is meant by degenerate codon? |
| A. | Two codons can be read in different frame o give different amino acids |
| B. | Codons are not having a gap |
| C. | Specific codon codes for specific amino acid |
| D. | Two codons can code for same amino acid |
| Answer» E. | |
| 43. |
The initiation codon is |
| A. | AUG |
| B. | UAA |
| C. | UAG |
| D. | UGA |
| Answer» B. UAA | |
| 44. |
AUG is the universal start codon. |
| A. | True |
| B. | False |
| Answer» C. | |
| 45. |
Which of the following codon calls for fMettRNA –fMet? |
| A. | CTA |
| B. | GUA |
| C. | AUG |
| D. | AUA |
| Answer» D. AUA | |