Explore topic-wise MCQs in Transcription.

This section includes 74 Mcqs, each offering curated multiple-choice questions to sharpen your Transcription knowledge and support exam preparation. Choose a topic below to get started.

51.

Which protein structure involves the binding of multiple polypeptides?
A. Primary structure
B. Tertiary structure
C. Quaternary structure
D. Secondary structure
Answer» D. Secondary structure
Discussion
52.

Disulfide bonds in proteins are categorized under which structure class?

A. More than one of these
B. Primary structure
C. C.
D. D.
Answer» B. Primary structure
Discussion
53.

Which of the following proteins are likely to contain leucine zipper domains?
A. Proteases
B. Transmembrane proteins
C. Lipases
D. Transcription factors
Answer» E.
Discussion
54.

"The addition of a CH3CO group to the N-terminus of a protein is the most common form of protein modification. This chemical modification is called ________."
A. Phosphorylation
B. Ubiquitination
C. Methylation
D. Acetylation
Answer» E.
Discussion
55.

Chloramphenicol prevents protein translation by which of the following mechanisms?
A. It blocks initiation of RNA chains by binding to RNA polymerase
B. It blocks the binding of aminoacyl tRNA to the A site of the ribosome
C. It blocks the peptidyl transferase reaction on ribosomes
D. It blocks the translocation reaction on ribosomes
Answer» D. It blocks the translocation reaction on ribosomes
Discussion
56.

Which of the following is a recognized mode of alternative splicing?
A. Exon skipping
B. Alternative donor site
C. Alternative acceptor site
D. All of these
Answer» E.
Discussion
57.

To which of the following structures in a typical molecule of tRNA is an amino acid attached?
A. D loop
B. Anticodon loop
C. CCA tail
D. Variable loop
Answer» D. Variable loop
Discussion
58.

How is splicing regulated at the level of cis-acting RNA sequence elements?

A. Splicing repressors bind splicing silencers and decrease nearby splice junction activity. Splicing activators bind splicing enhancers and increase likelihood of proximal sites as splice junction.
B. Splicing repressors bind splicing silencers and decrease nearby splice junction activity. Splicing activators bind splicing promoters and increase likelihood of proximal sites as splice junction.
C. Splicing repressors bind splicing silencers and increase nearby splice junction activity. Splicing activators bind splicing enhancers and decrease likelihood of proximal sites as splice junction.
D. Heterochromatin prevents alternative splicing whereas euchromatin promotes alternative splicing
Answer» B. Splicing repressors bind splicing silencers and decrease nearby splice junction activity. Splicing activators bind splicing promoters and increase likelihood of proximal sites as splice junction.
Discussion
59.

Researchers first identified parts of genes that are spliced out of mRNA and not included in the final protein product by observing that not all of the original gene hybridizes to the cognate mRNA. What are these regions called?
A. Inter genic regions
B. Micro RNAs
C. Exons
D. Introns
Answer» E.
Discussion
60.

Why is the post-transcriptional poly-A tail an important addition to a mRNA molecule?
A. The 3' tail signals the end of transcription by the RNA polymerase.
B. The poly-A tail is a part of the protein translated from the mRNA.
C. The poly-A tail facilitates the splicing of introns.
D. The tail adds stability to the transcript, controlling the time of degradation.
Answer» E.
Discussion
61.

What approximate percentage of total RNA content in a cell is messenger RNA (mRNA)?
A. 10 15%
B. 80 85%
C. 2 5%
D. 45 50%
Answer» D. 45 50%
Discussion
62.

Which of the following is not a category of RNA?
A. Long non-coding RNA
B. Piwi-interacting RNAs
C. MicroRNAs
D. Major RNAs
Answer» E.
Discussion
63.

All of the follwing are types of alternative RNA splicing except __________.
A. exon reversal
B. alternative 3' splicing
C. dual splice site
D. skipped exon
Answer» B. alternative 3' splicing
Discussion
64.

The process of formation of RNA is known as___________
A. Replication
B. DNA repair
C. Translation
D. Transcription
Answer» E.
Discussion
65.

In eukaryotes, in order to initiate transcription
A. RNA strand must be present
B. RNA polymerase must be present
C. Core promoter sequence must be present
D. None of these
Answer» D. None of these
Discussion
66.

Which of these subunits of RNA polymerase is totally required to initiate transcription?
A. alpha ( )
B. sigma ( )
C. omega ( )
D. beta ( )
Answer» C. omega ( )
Discussion
67.

In both prokaryotic and eukaryotic cells, the synthesis of protein chains is initiated with
A. Arginine
B. Methionine
C. Serina
D. Valine
Answer» C. Serina
Discussion
68.

The longest primary transcript is generated by
A. dystrophin gene
B. Tintin gene
C. neuromedin u
D. centromere protein A
Answer» B. Tintin gene
Discussion
69.

One end of tRNA matches genetic code in three-nucleotide sequences known as
A. codon
B. genetic code
C. blunt ends
D. anticodon
Answer» E.
Discussion
70.

Sigma factor is a component of
A. DNA ligase
B. DNA polymerase
C. Endonuclease
D. RNA polymerase
Answer» E.
Discussion
71.

The main function of tRNA with regards to protein synthesis is
A. Proofreading
B. identifies amino acids and transports them to ribosomes
C. Inhibits protein synthesis
D. all of the above
Answer» C. Inhibits protein synthesis
Discussion
72.

Transcription is the transfer of genetic information from
A. DNA to RNA
B. DNA to mRNA
C. mRNA to tRNA
D. tRNA to mRNA
Answer» C. mRNA to tRNA
Discussion
73.

A DNA sequence is read by an RNA polymerase that produces complementary antiparallel RNA strand known as
A. Hexa transcript
B. secondary transcript
C. primary transcript
D. tertiary transcript
Answer» D. tertiary transcript
Discussion
74.

During translation, which site in the ribosome allows for tRNA moelcules to enter the complex?

A. R site
B. E site
C. P site
D. A site
Answer» E.
Discussion