MCQOPTIONS
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MCQOPTIONS
This section includes 35 Mcqs, each offering curated multiple-choice questions to sharpen your Retroviridae knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The most common cause of inpatient admission to hospital for those living with HIV is ______. |
| A. | tuberculosis and other mycobacterial infections |
| B. | cardiovascular disorders |
| C. | bacterial infections |
| D. | none of these |
| Answer» C. bacterial infections | |
| 2. |
______ who need combination antiretroviral therapy receive it. |
| A. | Two in ten |
| B. | One in five |
| C. | Four in ten |
| D. | Three in five |
| Answer» D. Three in five | |
| 3. |
In 2015, the global prevalence of HIV infection was ______. |
| A. | 0.2% |
| B. | 0.4% |
| C. | 0.6% |
| D. | 0.8% |
| Answer» E. | |
| 4. |
HIV is a retrovirus that infects and colonizes cells in the ______. |
| A. | immune system |
| B. | immune system and the central nervous system |
| C. | endocrine system |
| D. | immune system and endocrine system |
| Answer» C. endocrine system | |
| 5. |
Each of the following statements concerning HIV is correct except: |
| A. | CD 4 protein on the T cell surface is one of the receptors |
| B. | There is appreciable antigenic diversity in the envelope glycoprotein of the virus |
| C. | One of the viral genes codes for a protein that augments the activity of the viral transcriptional promoter |
| D. | A major problem with testing for antibody to the virus is its cross-reactivity with HTLV-1 |
| Answer» E. | |
| 6. |
AIDS is most commonly caused by: |
| A. | HIV2 |
| B. | HIV1 |
| C. | HTLV-I |
| D. | HTLVII |
| Answer» C. HTLV-I | |
| 7. |
HTLV or HIV contain an extra gene not present in standard retroviruses: |
| A. | Gag |
| B. | Pol |
| C. | Env |
| D. | Tex |
| Answer» E. | |
| 8. |
HIV infects most commonly: |
| A. | CD 4 helper cells |
| B. | CD 8 cells |
| C. | Macrophages |
| D. | Neutrophils |
| Answer» B. CD 8 cells | |
| 9. |
Latent phase of HIV: |
| A. | Viral replication |
| B. | Sequestered in lymphoid tissue |
| C. | Infective |
| D. | Not infective |
| Answer» B. Sequestered in lymphoid tissue | |
| 10. |
Viruses that contain two complete copies of positive-strand RNA and the enzyme reverse transcriptase are: |
| A. | Toga viruses |
| B. | Rhabdoviruses |
| C. | Retroviruses |
| D. | Reoviruses |
| Answer» D. Reoviruses | |
| 11. |
Retrovirus causes: |
| A. | Burkitt s lymphoma |
| B. | Human T cell leukemia |
| C. | Encephalitis |
| D. | Uveal melanoma |
| Answer» C. Encephalitis | |
| 12. |
Virus having diploid ssRNA and reverse transcriptase: |
| A. | Retrovirus |
| B. | Arenavirus |
| C. | Paramyxovirus |
| D. | All of the above |
| Answer» B. Arenavirus | |
| 13. |
HIV virus contains: |
| A. | Single-stranded DNA |
| B. | Single-stranded RNA |
| C. | Double-stranded DNA |
| D. | Double-stranded RNA |
| Answer» C. Double-stranded DNA | |
| 14. |
Scott-Sheldon et al. (2013) found that ______ mediated the association between HIV status and alcohol use. |
| A. | depression |
| B. | stress |
| C. | income |
| D. | social support |
| Answer» C. income | |
| 15. |
HTLV-1 causes: |
| A. | AIDS |
| B. | Dementia |
| C. | Tropical spastic paraparesis |
| D. | D. |
| E. | |
| Answer» E. | |
| 16. |
Golub et al. (2010) surveyed 180 HIV-negative high-risk MSM and found that around 70% of participants reported that they would be likely to use PrEP if it were at least 80?fective in preventing HIV. Of those, over ______ reported that they would be likely to decrease condom use while on PrEP. |
| A. | 15% |
| B. | 25% |
| C. | 35% |
| D. | 45% |
| Answer» D. 45% | |
| 17. |
Studies suggest that fear of stigmatisation is especially strong among migrants. This is ______ which occurs when there is more than one type of difference. |
| A. | stigma enlargement |
| B. | stigma multiplication |
| C. | stigma amplification |
| D. | stigma magnification |
| Answer» D. stigma magnification | |
| 18. |
The causative agent of AIDS was discovered in: |
| A. | 1983 |
| B. | 1976 |
| C. | 1994 |
| D. | 1967 |
| Answer» B. 1976 | |
| 19. |
Who said that stigma is an attribute that is deeply discrediting and that reduces the bearer from a whole and usual person to a tainted, discounted one . |
| A. | Foucault |
| B. | Moscovici |
| C. | Vygotsky |
| D. | Goffman |
| Answer» E. | |
| 20. |
According to Crepaz, Hart and Marks (2004), people s ______ and viral load may promote unprotected sex. |
| A. | beliefs about cART |
| B. | knowledge of risk |
| C. | beliefs about transmission |
| D. | level of health literacy |
| Answer» B. knowledge of risk | |
| 21. |
The receptor through which M-tropic HIV strains bind? |
| A. | CCR5 |
| B. | CXCR4 |
| C. | CXCR5 |
| D. | Any of the above |
| Answer» B. CXCR4 | |
| 22. |
One in ten people ______ believed HIV infection can be transmitted through routes such as ______ |
| A. | incorrectly; kissing and spitting |
| B. | correctly; kissing and spitting |
| C. | incorrectly; needle sharing |
| D. | none of these |
| Answer» B. correctly; kissing and spitting | |
| 23. |
If you wished to prevent the attachment of the HIV virus to helper T cells, which molecule might best be targeted? |
| A. | gp41 |
| B. | gp120 |
| C. | Integrase |
| D. | P17 |
| Answer» C. Integrase | |
| 24. |
If it were possible to ablate the expression of the HIV pol gene, what another aspect of the virus s life cycle would be directly affected? |
| A. | Transcription of proviral DNA |
| B. | Production of viral mRNA |
| C. | Integration of proviral DNA |
| D. | Nucleocapsid |
| Answer» D. Nucleocapsid | |
| 25. |
True about HIV is: |
| A. | RNA virus |
| B. | Diploid genome |
| C. | Gag is gene coding or structural protein |
| D. | All are true |
| Answer» E. | |
| 26. |
Retroviruses are: |
| A. | + ss RNA |
| B. | ss RNA |
| C. | ds RNA |
| D. | None |
| Answer» B. ss RNA | |
| 27. |
Which of the following statements is not true for retroviruses? |
| A. | Retroviruses are causative agents for certain kinds of cancer in man |
| B. | The genetic material in mature retroviruses is RNA |
| C. | Retroviruses carry the gene for RNA-dependent DNA polymerase |
| D. | DNA is not present at any stage in the life cycle of retroviruses |
| Answer» E. | |
| 28. |
The RNA virus that produces DNA that can integrate with the host genome: |
| A. | Papovavirus |
| B. | Reovirus |
| C. | Picornavirus |
| D. | Retrovirus |
| Answer» E. | |
| 29. |
HIV: |
| A. | Is a lentivirus |
| B. | Has single-stranded RNA |
| C. | Genome has three structural genes |
| D. | All are true |
| Answer» E. | |
| 30. |
Which is a non-structural gene of HIV? |
| A. | Gag |
| B. | Env |
| C. | Tat |
| D. | Pol |
| Answer» D. Pol | |
| 31. |
What is the sequence of HIV following entry into a host cell? |
| A. | RNA DNA RNA |
| B. | RNA DNA |
| C. | DNA RNA |
| D. | DNA RNA DNA |
| Answer» B. RNA DNA | |
| 32. |
The first country in SEAR to report AIDS was: |
| A. | India |
| B. | Sri Lanka |
| C. | Bangladesh |
| D. | Thailand |
| Answer» E. | |
| 33. |
The first case of HIV was reported in: |
| A. | 1981 |
| B. | 1984 |
| C. | 1986 |
| D. | 1988 |
| Answer» B. 1984 | |
| 34. |
What is p24? |
| A. | Envelope gene in HIV |
| B. | Genome of HIV |
| C. | Core antigen of HIV |
| D. | Shell antigen of HIV |
| Answer» D. Shell antigen of HIV | |
| 35. |
The nef gene in HIV is for: |
| A. | Enhancing expression of genes |
| B. | Enhancing viral replication |
| C. | Decreasing viral replication |
| D. | Maceration |
| Answer» D. Maceration | |