88 + Mcqs in General Page 1 McqOptions

1.	Segments of antigen that are recognized by antibody are
A.	Memory regions
B.	Epitopes
C.	Nondeterminants
D.	Self limitation
Answer» C. Nondeterminants

Discussion

2.	Rh factor is named after
A.	Monkey
B.	Drosphila
C.	Rat
D.	Man
Answer» B. Drosphila

Discussion

3.	Persons with blood group A posses
A.	Antigen A and antibodies b
B.	Antigen A and antibodies a
C.	No antigen but antibodies and b
D.	antigens A and B but no antobodies
Answer» B. Antigen A and antibodies a

Discussion

4.	Rh- mother carries Rh+ foetus. The foetus is at a risk of disease called
A.	Haemophilia
B.	Haemolytic disease
C.	Tuberculosis
D.	Syphilis
Answer» C. Tuberculosis

Discussion

5.	Progenitors formed in bone marrow but differentiating elsewhere are
A.	Pre-NK cells
B.	Pre-erythroblasts
C.	Pre-T cells
D.	Myeloblasts
Answer» D. Myeloblasts

Discussion

6.	Resistance developed in an individual as a result of antigenic stimulus is
A.	Natural immunity
B.	Active acquired immunity
C.	Passive acquired immunity
D.	Artificial immunity
Answer» C. Passive acquired immunity

Discussion

7.	The branch of biology involved in the study of immune systems in all organisms is called_________.
A.	Botany
B.	Microbiology
C.	Immunology
D.	Biotechnology
Answer» D. Biotechnology

Discussion

8.	Which of the following cells is involved in cell-mediated immunity?
A.	T-cells
B.	B-cells
C.	Mast cells
D.	Both T and B cells
Answer» B. B-cells

Discussion

9.	Which of the following statements is true about Passive Immunity?
A.	This immunity causes reactions
B.	This immunity develops immediately
C.	This immunity lasts only for a few weeks or months
D.	All of the above.
Answer» E.

Discussion

10.	The common disorders caused by a poor immune system include ________
A.	Epidemic Diseases
B.	Deficiency diseases
C.	Autoimmune diseases
D.	None of the above
Answer» B. Deficiency diseases

Discussion

11.	Neutrophils, basophil, lymphocytes, eosinophil and monocytes are examples of ________.
A.	Physical barrier
B.	Cellular barriers
C.	Cytokine barriers
D.	Physiological barriers
Answer» C. Cytokine barriers

Discussion

12.	B-cells and T-cells are two types of cells involved in _______________.
A.	Innate Immunity
B.	Active immunity
C.	Passive immunity
D.	Acquired immunity
Answer» E.

Discussion

13.	Central tolerance refers to which of the following processes?
A.	Destruction of lymphocytes that are not specific for self-antigens
B.	Production of self-antigens that are specific for lymphocytes
C.	Destruction of self-antigens that are specific for lymphocytes
D.	Destruction of lymphocytes that are specific for self-antigens
Answer» E.

Discussion

14.	In the developing fetus, prenatal hematopoiesis (the differentiation and development of immune cells) is not generally known to occur in which of the following organs?
A.	Liver
B.	Spleen
C.	Lymph nodes
D.	Appendix
Answer» E.

Discussion

15.	Major histocompatibility complex (MHC) refers to a large group of genes that code for proteins that play an essential role in which of the following?
A.	Phagocytosis by macrophages
B.	Antigen presentation to T lymphocytes
C.	Phagocytosis by neutrophils
D.	Antigen presentation to B lymphocytes
Answer» C. Phagocytosis by neutrophils

Discussion

16.	Which portion of an antibody provides antigen-binding sites?
A.	Light chain
B.	Constant portion
C.	Heavy chain
D.	Variable portion
Answer» E.

Discussion

17.	Which of the following is not one of the three main antigen-presenting cell types?
A.	Dendritic cells
B.	B lymphocytes
C.	Natural killer cells
D.	Macrophages
Answer» D. Macrophages

Discussion

18.	Recognition of self vs. non-self by the adaptive immune system in humans is accomplished in which of the following ways?
A.	Exposure of B cells to the body s own antigens in the thymus
B.	Exposure of B cells to the body s own antigens in the bursa of Fabricius
C.	Exposure of T cells to the body s own antigens in the bursa of Fabricius
D.	Exposure of T cells to the body s own antigens in the thymus
Answer» E.

Discussion

19.	Humoral immunity is a type of adaptive immunity that results in the circulation of which of the following throughout the blood?
A.	Antigens
B.	Macrophages
C.	Natural killer cells
D.	Antibodies
Answer» E.

Discussion

20.	Myelogenous leukemias are caused by the cancerous production of innate (non-specific) immune system cells: in which tissue is such production most likely to occur?
A.	Bone marrow
B.	Thymus
C.	Spleen
D.	Lymph nodes
Answer» B. Thymus

Discussion

21.	The ability of the immune system to recognize self-antigens versus nonself antigen is an example of:
A.	Specific immunity
B.	Tolerance
C.	Cell-mediated immunity
D.	Antigenic immunity
Answer» C. Cell-mediated immunity

Discussion

22.	Cell-mediated immunity is carried out by .. while humoral immunity is mainly carried out by ..
A.	B cells/T cells
B.	Epitopes/Antigens
C.	T cells/B cells
D.	Antibodies/Antigens
Answer» D. Antibodies/Antigens

Discussion

23.	Monoclonal antibodies recognize a single:
A.	Antigen
B.	Bacterium
C.	Epitope
D.	Virus
Answer» D. Virus

Discussion

24.	B Cells are activated by
A.	Complement
B.	Antibody
C.	Interferon
D.	Antigen
Answer» E.

Discussion

25.	Fusion between a plasma cell and a tumor cell creates a
A.	Myeloma
B.	Natural killer cell
C.	Lymphoblast
D.	Hybridoma
Answer» E.

Discussion

26.	A rare disease congenital agammaglobulinemia is caused due to abnormality in __________________
A.	humoral antibody
B.	cell-mediated immunity
C.	acidic/alkaline pH
D.	homeostasis
Answer» B. cell-mediated immunity

Discussion

27.	B and T lymphocytes arise from _____________
A.	hematopoietic stem cells
B.	germ cells
C.	somatic cells
D.	spermatocytes
Answer» B. germ cells

Discussion

28.	Humoral immunity is mediated by ______________
A.	mast cells
B.	neutrophils
C.	lymphocytes
D.	leukocytes
Answer» D. leukocytes

Discussion

29.	Adaptive immune responses are more specific that innate immune responses.
A.	True
B.	False
Answer» B. False

Discussion

30.	Which type of interferons is associated with an antiviral innate response?
A.	Type I
B.	Type II
C.	Type III
D.	Type IV
Answer» B. Type II

Discussion

31.	Which type of immune cells are responsible for eradicating intracellular pathogens?
A.	natural killer cells
B.	mast cells
C.	neurons
D.	specific lymphocytes
Answer» B. mast cells

Discussion

32.	Which of the following is an antimicrobial peptide synthesized by lymphocytes?
A.	adhesins
B.	condensins
C.	defensins
D.	complement
Answer» D. complement

Discussion

33.	Innate immune responses are accompanied by inflammation.
A.	True
B.	False
Answer» B. False

Discussion

34.	Which of the following drug acts by stimulating toll-like receptors (TLRs)?
A.	Doxorubicin
B.	Neosporin
C.	Aldara
D.	Vimentin
Answer» D. Vimentin

Discussion

35.	The phagocytes can recognize pathogens by means of _____________________
A.	necrosis factor
B.	complement activation
C.	pattern recognition receptors
D.	adhesion molecules
Answer» D. adhesion molecules

Discussion

36.	Which of the following immunity is called the first line of defence?
A.	Innate Immunity
B.	Active immunity
C.	Passive immunity
D.	Acquired immunity
Answer» B. Active immunity

Discussion

37.	Which of the following group of pathogens always reside intracellularly in the host?
A.	virus
B.	fungi
C.	molds
D.	bacteria
Answer» B. fungi

Discussion

38.	What is not required in the innate immune responses?
A.	antigen
B.	strong immunity
C.	pathogen
D.	previous contact
Answer» E.

Discussion

39.	Cells Involved In Innate Immunity are_________.
A.	Phagocytes
B.	Macrophages
C.	Natural Killer Cells
D.	All of the above
Answer» E.

Discussion

40.	Who discovered the vaccination against smallpox?
A.	Louis Pasteur
B.	Francis Crick
C.	Barbara McClintock
D.	Edward Jenner
Answer» E.

Discussion

41.	For the body to develop immunologic tolerance, production of ____________________ must be prevented.
A.	antibodies
B.	antigens
C.	autoantibodies
D.	lymphocytes
Answer» D. lymphocytes

Discussion

42.	In case of acquired immune system, a secondary immune response is generated by the ______________
A.	memory B-cells
B.	germ cells
C.	lymphoid tissues
D.	antigens
Answer» B. germ cells

Discussion

43.	Some of the activated B-cells lead to the formation of short-lived ______________________
A.	plasma cells
B.	evanescent waves
C.	memory cells
D.	thymus cells
Answer» B. evanescent waves

Discussion

44.	B-cells arise from ______________________
A.	progenitor cells
B.	antigens
C.	antibodies
D.	natural killer cells
Answer» B. antigens

Discussion

45.	Antigens that do not require the involvement of T-cells for the activation of B-cells are _____________________
A.	thymus-dependent
B.	thymus-independent
C.	intracellular pathogens
D.	facultative anaerobes
Answer» C. intracellular pathogens

Discussion

46.	Who proposed the clonal selection theory?
A.	James Watson
B.	Niels Jerne
C.	Francis Crick
D.	Frank MacFarlane Burnet
Answer» E.

Discussion

47.	According to the instructive model the antigen instructs lymphocytes to produce antibodies.
A.	True
B.	False
Answer» B. False

Discussion

48.	B-lymphocytes that do not differentiate into plasma cells are called _______________________
A.	T-lymphocytes
B.	Helper T-cells
C.	Memory B cells
D.	Memory T-cells
Answer» D. Memory T-cells

Discussion

49.	Plasma cells possess extensive smooth endoplasmic reticulum.
A.	True
B.	False
Answer» C.

Discussion

50.	Skin, body hair, cilia, eyelashes, the respiratory tract and the gastrointestinal tract are examples of ________.
A.	Physical barrier
B.	Cellular barriers
C.	Cytokine barriers
D.	Physiological barriers
Answer» B. Cellular barriers

Discussion

Explore topic-wise MCQs in Immune Response.

Segments of antigen that are recognized by antibody are

Rh factor is named after

Persons with blood group A posses

Rh- mother carries Rh+ foetus. The foetus is at a risk of disease called

Progenitors formed in bone marrow but differentiating elsewhere are

Resistance developed in an individual as a result of antigenic stimulus is

The branch of biology involved in the study of immune systems in all organisms is called_________.

Which of the following cells is involved in cell-mediated immunity?

Which of the following statements is true about Passive Immunity?

The common disorders caused by a poor immune system include ________

Neutrophils, basophil, lymphocytes, eosinophil and monocytes are examples of ________.

B-cells and T-cells are two types of cells involved in _______________.

Central tolerance refers to which of the following processes?

In the developing fetus, prenatal hematopoiesis (the differentiation and development of immune cells) is not generally known to occur in which of the following organs?

Major histocompatibility complex (MHC) refers to a large group of genes that code for proteins that play an essential role in which of the following?

Which portion of an antibody provides antigen-binding sites?

Which of the following is not one of the three main antigen-presenting cell types?

Recognition of self vs. non-self by the adaptive immune system in humans is accomplished in which of the following ways?

Humoral immunity is a type of adaptive immunity that results in the circulation of which of the following throughout the blood?

Myelogenous leukemias are caused by the cancerous production of innate (non-specific) immune system cells: in which tissue is such production most likely to occur?

The ability of the immune system to recognize self-antigens versus nonself antigen is an example of:

Cell-mediated immunity is carried out by .. while humoral immunity is mainly carried out by ..

Monoclonal antibodies recognize a single:

B Cells are activated by

Fusion between a plasma cell and a tumor cell creates a

A rare disease congenital agammaglobulinemia is caused due to abnormality in __________________

B and T lymphocytes arise from _____________

Humoral immunity is mediated by ______________

Adaptive immune responses are more specific that innate immune responses.

Which type of interferons is associated with an antiviral innate response?

Which type of immune cells are responsible for eradicating intracellular pathogens?

Which of the following is an antimicrobial peptide synthesized by lymphocytes?

Innate immune responses are accompanied by inflammation.

Which of the following drug acts by stimulating toll-like receptors (TLRs)?

The phagocytes can recognize pathogens by means of _____________________

Which of the following immunity is called the first line of defence?

Which of the following group of pathogens always reside intracellularly in the host?

What is not required in the innate immune responses?

Cells Involved In Innate Immunity are_________.

Who discovered the vaccination against smallpox?

For the body to develop immunologic tolerance, production of ____________________ must be prevented.

In case of acquired immune system, a secondary immune response is generated by the ______________

Some of the activated B-cells lead to the formation of short-lived ______________________

B-cells arise from ______________________

Antigens that do not require the involvement of T-cells for the activation of B-cells are _____________________

Who proposed the clonal selection theory?

According to the instructive model the antigen instructs lymphocytes to produce antibodies.

B-lymphocytes that do not differentiate into plasma cells are called _______________________

Plasma cells possess extensive smooth endoplasmic reticulum.

Skin, body hair, cilia, eyelashes, the respiratory tract and the gastrointestinal tract are examples of ________.