43 + Mcqs in General Page 1 McqOptions

1.	A patient of acute lymphocytic leukemia with fever and neutropenia develops diarrhea after administration of amoxicillin therapy, which of the following organism is most likely to be the causative agent?
A.	Salmonella typhi
B.	Clostridium difficle
C.	Clostridium perfringens
D.	Shigella flexneri
Answer» C. Clostridium perfringens

Discussion

2.	An 18-year old male presented with acute onset descending paralysis of 3 days duration. There is also a history of blurring of vision for the same duration. On examination, the patient has quadriparesis with areflexia. Both the pupils are non-reactive. The most probable diagnosis is:
A.	Poliomyelitis
B.	Botulism
C.	Diphtheria
D.	Porphyria
Answer» C. Diphtheria

Discussion

3.	All are true regarding clostridium tetani except:
A.	Produces heat resistant spores
B.	Incubation period 6-11 days
C.	E primary doses of vaccine needed for full protection
D.	Man-to-man transmission is seen
Answer» E.

Discussion

4.	True regarding pseudomembranous colitis are all except:
A.	It is caused by Clostridium difficle
B.	The organism is a normal commensal of gut
C.	It is due to the production of phospholipase A
D.	It is treated by vancomycin
Answer» D. It is treated by vancomycin

Discussion

5.	The most effective way of preventing tetanus is:
A.	Surgical debridement and toilet
B.	Hyperbaric oxygen
C.	Antibiotics
D.	Tetanus toxoid
Answer» E.

Discussion

6.	A 10-year old boy following a road traffic accident presents to the casualty with a contaminated wound over the left leg. He has received his completed primary immunization before preschool age and received a booster of DT at school entry age. All of the following can be done except:
A.	Injection of TT
B.	Injection of human antiserum
C.	Broad-spectrum antibiotics
D.	Wound debridement and cleaning
Answer» C. Broad-spectrum antibiotics

Discussion

7.	True about clostridium tetani:
A.	It is Gram +ve
B.	Drum stick appearance
C.	Grows in aerobic environment
D.	It is Gram -ve
Answer» C. Grows in aerobic environment

Discussion

8.	A person has received complete immunization against tetanus 10 years ago. Now he presents with a clean wound without any lacerations from an injury sustained 2.5 hours ago. He should now be given:
A.	Full course of tetanus toxoid
B.	Single-dose of tetanus toxoid
C.	Human tet. Globulin
D.	Human tet. Globulin and single dose of toxoid
Answer» C. Human tet. Globulin

Discussion

9.	Which of the following regarding Clostridium tetani is false?
A.	Soil sand intestine of human and animals are the reservoirs
B.	Predominantly seen in dry and winter season
C.	Transmission through contaminated wounds
D.	No herd immunity or seen
Answer» C. Transmission through contaminated wounds

Discussion

10.	True about gas gangrene:
A.	Underlying skin and muscle are normal
B.	Caused by tetanospasmin toxin
C.	Muscle rigidity and spasm are characteristic
D.	Most common organism implicated is Cl. Perfringes
Answer» E.

Discussion

11.	Onchocerciasis:
A.	Is transmitted by mosquito bite
B.	Is only found in West Africa
C.	Causes nodular lesions in the eyes and skin
D.	Causes corneal scarring
Answer» D. Causes corneal scarring

Discussion

12.	The following are true about hepatitis B:
A.	It is a RNA virus
B.	Immunity can be acquired by vaccination with a live attenuated virus
C.	Persistent presence of HBsAg increases the risk of chronic liver disease
D.	The average incubation period is 30 days
Answer» D. The average incubation period is 30 days

Discussion

13.	The following are true about leprosy:
A.	It is caused by an acid fast bacteria
B.	It causes facial nerve palsy
C.	Tuberculoid leprosy occurs in patients with poor cellular immunity
D.	More bacilli are found in the skin of patients with lepromatous leprosy than tuberculoid leprosy.
Answer» B. It causes facial nerve palsy

Discussion

14.	With regard to Treponema pallidum:
A.	The bacteria can be found in lesions of primary syphilis
B.	The bacteria can be found in lesions of secondary syphilis
C.	The bacteria can be found in the cerebrospinal fluid of tertiary syphilis
D.	VDRL is specific for Treponema pallidum infection
Answer» B. The bacteria can be found in lesions of secondary syphilis

Discussion

15.	True about the treatment of gas gangrene after contaminated road traffic accident:
A.	IV administration of anti-gas gangrene serum
B.	Penicillin
C.	Immediate suturing
D.	Surgical debridement
Answer» B. Penicillin

Discussion

16.	The following are true about Clostridium tetani:
A.	It is a Gram positive bacilli with terminal spore
B.	Tetanus can occur weeks after the initial infection
C.	The symptoms of tetanus is produced by an endotoxin
D.	Gas gangrene can result from Clostridium tetani infection
Answer» B. Tetanus can occur weeks after the initial infection

Discussion

17.	Not true about Botulinum toxin:
A.	Short life span
B.	Increased acetylcholine release
C.	Used for treatment in Blepharospasm, static and dynamic wrinkles
D.	Irreversibly decreases Ach in NM junction
Answer» B. Increased acetylcholine release

Discussion

18.	Subterminal spores are found in:
A.	Clostridium sordelli
B.	Clostridium sporogenes
C.	Clostridium difficle
D.	Clostridium tertium
Answer» B. Clostridium sporogenes

Discussion

19.	Most important and potential agent that can be used for bioterrorism.
A.	Plague
B.	Smallpox
C.	TB
D.	Clostridium botulinum
Answer» E.

Discussion

20.	The following statements are true regarding botulism except:
A.	Infant botulism is caused by ingestion of preformed toxin
B.	Botulinum A, B, E, and F cause human disease
C.	The gene for botulinum toxin is coded by bacteriophage
D.	Cl. bratii may cause botulism
Answer» B. Botulinum A, B, E, and F cause human disease

Discussion

21.	Gastrointestinal enteritis nectoticans caused by:
A.	Cl. Difficile
B.	Cl. Perfringens
C.	Botulinum
D.	C. jejuni
Answer» C. Botulinum

Discussion

22.	Which species of Clostridium does not cause gangrene?
A.	Cl. Perfringens
B.	Cl. Histolyticum
C.	C. novyii
D.	C. sporogenes
Answer» E.

Discussion

23.	Nagle s reaction is shown by:
A.	Cl. Tetani
B.	Cl. Botulinum
C.	Cl. Perfringens
D.	Cl. Septicum
Answer» D. Cl. Septicum

Discussion

24.	Regarding gas gangrene one of the following is correct:
A.	It is due to Clostridium botulinum infection
B.	Clostridial species are gram-negative anaerobes forming spores
C.	The clinical features are due to the release of protein endotoxin
D.	Gas is invariably present in the muscle com-part-ments
Answer» E.

Discussion

25.	Gas gangrene is/are caused by:
A.	Cl. Novyi
B.	Cl. septicum
C.	Cl. Histolyticum
D.	Cl. Perfringens
Answer» B. Cl. septicum

Discussion

26.	The following statements are true regarding Clostridium perfringens except:
A.	It is the commonest cause of gas gangrene
B.	It is normally present in human feces
C.	The principal toxin of C. perforin genes is the alpha-toxin
D.	Gas gangrene producing strains of C. perforin genes produces heat resistant spores
Answer» E.

Discussion

27.	Which among the following species causes tuberculosis?
A.	Mycobacterium leprae
B.	Mycobacterium kansasii
C.	Mycobacterium bovis
D.	Mycobacterium ulcerans
Answer» D. Mycobacterium ulcerans

Discussion

28.	Schick Test is used for detection of which of the following disease?
A.	Diphtheria
B.	Tuberculosis
C.	Erythrasma
D.	Botulism
Answer» B. Tuberculosis

Discussion

29.	Erythrasma is caused by which of the following microorganism?
A.	Corynebacterium diphtheriae
B.	Corynebacterium ulcerans
C.	Corynebacterium minutissimum
D.	Listeria monocytogenes
Answer» D. Listeria monocytogenes

Discussion

30.	Which of the following inactivates IgA antibodies?
A.	Cord factor
B.	Diphthin
C.	Neuroaminidase
D.	K antigens
Answer» C. Neuroaminidase

Discussion

31.	Patients with botulism are treated with monovalent antitoxin.
A.	True
B.	False
Answer» C.

Discussion

32.	Toxin A involved in pseudomembranous colitis is a type of _______________
A.	endotoxin
B.	enterotoxin
C.	cytotoxin
D.	neurotoxin
Answer» C. cytotoxin

Discussion

33.	What pressure of oxygen is used in the treatment involving the use of hyperbaric oxygen?
A.	1
B.	5
C.	100
D.	3
Answer» E.

Discussion

34.	Which serovar of C. botulinum occurs mainly in the sediments of the Great Lakes?
A.	A
B.	B
C.	E
D.	F
Answer» D. F

Discussion

35.	Which of the following temperature is suitable for the multiplication of clostridia spores?
A.	109 to116 degree F
B.	100 degree F
C.	-2 to 16 degree F
D.	30-40 degree F
Answer» B. 100 degree F

Discussion

36.	Clostridium perfringens type A occurs as a natural flora of _____________
A.	stomach
B.	mouth
C.	intestine
D.	eyes
Answer» D. eyes

Discussion

37.	__________________ is a hyaluronidase that may aid invasiveness of C.perfringens.
A.	alpha toxin
B.	theta toxin
C.	toxin
D.	toxin
Answer» D. toxin

Discussion

38.	Clostridium botulinum food poisoning is due to
A.	invasion of bacteria in the intestine
B.	preformed toxin
C.	both (a) and (b)
D.	none of the above
Answer» C. both (a) and (b)

Discussion

39.	Food poisoning strains of Clostridium perfringens belong to
A.	type A
B.	type B
C.	type C
D.	type D
Answer» B. type B

Discussion

40.	Which of the following organisms produces neurotoxin as a virulence factor?
A.	Bacillus anthracis
B.	Clostridium tetani
C.	Streptococcus pneumoniae
D.	Staphylococcus aureus
Answer» C. Streptococcus pneumoniae

Discussion

41.	Booster immunizations should be given every 10 years.
A.	True
B.	False
Answer» B. False

Discussion

42.	Which of the following types of Clostridium perfringens produces alpha toxin most abundantly?
A.	Type A
B.	Type B
C.	Type C
D.	Type D
Answer» B. Type B

Discussion

43.	Regarding Clostridium perfringens gas gangrene, all are true, except:
A.	Commonest cause of gas gangrene
B.	Naegleria reaction positive
C.	Most common toxin is hyaluronidase
D.	Food poisoning strain of Clostridium per fringe produced heat resistant spores.
Answer» D. Food poisoning strain of Clostridium per fringe produced heat resistant spores.

Discussion

Explore topic-wise MCQs in Clostridium.

A patient of acute lymphocytic leukemia with fever and neutropenia develops diarrhea after administration of amoxicillin therapy, which of the following organism is most likely to be the causative agent?

An 18-year old male presented with acute onset descending paralysis of 3 days duration. There is also a history of blurring of vision for the same duration. On examination, the patient has quadriparesis with areflexia. Both the pupils are non-reactive. The most probable diagnosis is:

All are true regarding clostridium tetani except:

True regarding pseudomembranous colitis are all except:

The most effective way of preventing tetanus is:

A 10-year old boy following a road traffic accident presents to the casualty with a contaminated wound over the left leg. He has received his completed primary immunization before preschool age and received a booster of DT at school entry age. All of the following can be done except:

True about clostridium tetani:

A person has received complete immunization against tetanus 10 years ago. Now he presents with a clean wound without any lacerations from an injury sustained 2.5 hours ago. He should now be given:

Which of the following regarding Clostridium tetani is false?

True about gas gangrene:

Onchocerciasis:

The following are true about hepatitis B:

The following are true about leprosy:

With regard to Treponema pallidum:

True about the treatment of gas gangrene after contaminated road traffic accident:

The following are true about Clostridium tetani:

Not true about Botulinum toxin:

Subterminal spores are found in:

Most important and potential agent that can be used for bioterrorism.

The following statements are true regarding botulism except:

Gastrointestinal enteritis nectoticans caused by:

Which species of Clostridium does not cause gangrene?

Nagle s reaction is shown by:

Regarding gas gangrene one of the following is correct:

Gas gangrene is/are caused by:

The following statements are true regarding Clostridium perfringens except:

Which among the following species causes tuberculosis?

Schick Test is used for detection of which of the following disease?

Erythrasma is caused by which of the following microorganism?

Which of the following inactivates IgA antibodies?

Patients with botulism are treated with monovalent antitoxin.

Toxin A involved in pseudomembranous colitis is a type of _______________

What pressure of oxygen is used in the treatment involving the use of hyperbaric oxygen?

Which serovar of C. botulinum occurs mainly in the sediments of the Great Lakes?

Which of the following temperature is suitable for the multiplication of clostridia spores?

Clostridium perfringens type A occurs as a natural flora of _____________

__________________ is a hyaluronidase that may aid invasiveness of C.perfringens.

Clostridium botulinum food poisoning is due to

Food poisoning strains of Clostridium perfringens belong to

Which of the following organisms produces neurotoxin as a virulence factor?

Booster immunizations should be given every 10 years.

Which of the following types of Clostridium perfringens produces alpha toxin most abundantly?

Regarding Clostridium perfringens gas gangrene, all are true, except: