What are the major stability problems which result in poor bioavailability of any orally administered drugs?

Degradation by salivary amylase

Degradation of the drug in inactive form

Interaction with the excipients and degradation in an inactive form

Explore topic-wise MCQs in Drug Biotechnology.

This section includes 3 Mcqs, each offering curated multiple-choice questions to sharpen your Drug Biotechnology knowledge and support exam preparation. Choose a topic below to get started.

1.	What are the major stability problems which result in poor bioavailability of any orally administered drugs?
A.	Acidic degradation
B.	Degradation by salivary amylase
C.	Degradation of the drug in inactive form
D.	Interaction with the excipients and degradation in an inactive form
Answer» E.

Discussion

2.	Drug having a small partition coefficient can rapidly penetrate the lipid membrane but diffusion through the unstirred water layer is a rate-limiting step.
A.	True
B.	False
Answer» C.

Discussion

3.	Acidic drugs are best absorbed through the stomach and basic drugs are best absorbed through the intestine.
A.	True
B.	False
Answer» B. False

Discussion

Explore topic-wise MCQs in Drug Biotechnology.

What are the major stability problems which result in poor bioavailability of any orally administered drugs?

Drug having a small partition coefficient can rapidly penetrate the lipid membrane but diffusion through the unstirred water layer is a rate-limiting step.

Acidic drugs are best absorbed through the stomach and basic drugs are best absorbed through the intestine.