MCQOPTIONS
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MCQOPTIONS
This section includes 10 Mcqs, each offering curated multiple-choice questions to sharpen your Drug Biotechnology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Bioavailability of glutathione in the body doesn t determine the threshold of a toxic response. |
| A. | True |
| B. | False |
| Answer» C. | |
| 2. |
Free radicals are more dangerous than electrophiles. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 3. |
How are free radicals generated in the human body? |
| A. | Through cytochrome P-450 system |
| B. | NADPH cytochrome P-450 reductase |
| C. | NADPH reductase |
| D. | Through cytochrome P-350 system |
| Answer» C. NADPH reductase | |
| 4. |
How are electrophiles generated? |
| A. | Through cytochrome P-450 system |
| B. | NADPH cytochrome P-450 reductase |
| C. | Different Flavin containing reductase |
| D. | Through cytochrome P-350 system |
| Answer» B. NADPH cytochrome P-450 reductase | |
| 5. |
Which of the following will be an example of inorganic free radicle? |
| A. | H<sub>2</sub>O<sub>2</sub> and O<sub>2</sub><sup> </sup> |
| B. | Aflatoxin |
| C. | Quinones |
| D. | Benzopyrene |
| Answer» B. Aflatoxin | |
| 6. |
Which xenobiotics yield free radicles on metabolic activation? |
| A. | Thalidomide |
| B. | Aflatoxin |
| C. | Quinones |
| D. | Benzopyrene |
| Answer» D. Benzopyrene | |
| 7. |
Electrophiles are deficient of pair of electrons and free radicals contain an odd number of electrons. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 8. |
What is the body s defence against electrophiles? |
| A. | Their inactivation by conjugation with glucagon |
| B. | Their inactivation by conjugation with glutamine |
| C. | Their inactivation by conjugation with glucuronic acid |
| D. | Their inactivation by conjugation with glutathione |
| Answer» E. | |
| 9. |
Which of the following is an example of electrophiles? |
| A. | Thalidomide |
| B. | Aflatoxin |
| C. | Epoxides |
| D. | Benzopyrene |
| Answer» D. Benzopyrene | |
| 10. |
Which of the following statement rightly states bioactivation ? |
| A. | Formation of high reactive metabolites which interact with tissues to precipitate toxic compounds |
| B. | Formation chelating agents |
| C. | Formation of enzymes which can lyse toxic compounds |
| D. | Stimulating the immune systems to initiate the formation of t cells |
| Answer» B. Formation chelating agents | |