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This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Drug Biotechnology knowledge and support exam preparation. Choose a topic below to get started.
1. |
Macrophages with a high content of EPA produce less TNF and IL-l. |
A. | True |
B. | False |
Answer» B. False | |
2. |
How does Eicosapentaenoic acid functions to decrease the inflammation rate? |
A. | Decrease Prostaglandin production |
B. | Don t form prostaglandin |
C. | Induce the formation of prostaglandins at certain times |
D. | The prostaglandins, thromboxane produced from EPA are less active |
Answer» E. | |
3. |
Which of the following has the least GI effect and derived from parent NSAIDs? |
A. | Piroxicam |
B. | Phenylbutazone |
C. | NO-NSAIDs |
D. | Indomethacin |
Answer» D. Indomethacin | |
4. |
Why there are side effects of NSAIDs? |
A. | Inhibition of COX 1 |
B. | Inhibition of COX 2 |
C. | Inhibition of COX 3 |
D. | Inhibition of COX 4 |
Answer» B. Inhibition of COX 2 | |
5. |
Which of the following responsible for inflammatory response mainly? |
A. | COX 1 |
B. | COX 2 |
C. | COX 3 |
D. | COX 4 |
Answer» C. COX 3 | |
6. |
Which of the following is also known as housekeeping enzyme ? |
A. | COX 1 |
B. | COX 2 |
C. | COX 3 |
D. | COX 4 |
Answer» B. COX 2 | |
7. |
Which of the following is a pro-drug and related to indomethacin? |
A. | Piroxicam |
B. | Phenylbutazone |
C. | Sulindac |
D. | Indomethacin |
Answer» D. Indomethacin | |
8. |
Which of the following pyrazolone derivative s has toxic side effects? |
A. | Piroxicam |
B. | Phenylbutazone |
C. | Ibuprofen |
D. | Indomethacin |
Answer» C. Ibuprofen | |
9. |
Which of the following cannot be tolerated, rheumatoid arthritis patient? |
A. | Piroxicam |
B. | Phenylbutazone |
C. | Ibuprofen |
D. | Indomethacin |
Answer» E. | |
10. |
Which of the following has the same potency as ASA and better tolerated by patients? |
A. | Piroxicam |
B. | Phenylbutazone |
C. | Ibuprofen |
D. | Indomethacin |
Answer» D. Indomethacin | |
11. |
Which of the following has a half-life of 45 Hrs? |
A. | Piroxicam |
B. | Phenylbutazone |
C. | Ibuprofen |
D. | Indomethacin |
Answer» B. Phenylbutazone | |
12. |
How does NSAIDs work? |
A. | Inhibit arachidonic acid |
B. | Inhibit Endoperoxide intermediate |
C. | Inhibit Prostaglandin and thromboxane synthesis |
D. | Inhibit cyclooxygenase |
Answer» E. | |
13. |
Which is the predominant form of cyclooxygenase enzyme? |
A. | COX 1 |
B. | COX 2 |
C. | COX 3 |
D. | COX 4 |
Answer» B. COX 2 | |