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This section includes 10 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
1. |
How can we remove supercoils from cccDNA? |
A. | Treat with DNase |
B. | Treat with detergent |
C. | Treat with endonuclease |
D. | Application of heat |
Answer» B. Treat with detergent | |
2. |
What is the relation between linking number (Lk), writing number (Wr) and twist number (Tw)? |
A. | Lk = Tw – Wr |
B. | Lk = Wr – Tw |
C. | Tw = Lk – Wr |
D. | Tw = Lk + Wr |
Answer» D. Tw = Lk + Wr | |
3. |
Twist and writhe are interconvertible. |
A. | True |
B. | False |
Answer» B. False | |
4. |
Interwound writhe and spiral writhe are topologically different. |
A. | True |
B. | False |
Answer» C. | |
5. |
Plectonomic writhe is __________ |
A. | Cylindrical axis winding |
B. | Long axis twisted around itself |
C. | Helical turns of one strand about the other |
D. | Number of encounters of the two strands of a helix |
Answer» C. Helical turns of one strand about the other | |
6. |
3 – dimension structure of cccDNA is ___________ |
A. | Nicked |
B. | Supercoiled |
C. | Flat |
D. | Torsionally stressed |
Answer» E. | |
7. |
Linking number is the sum of which geometric components? |
A. | Twist and writhe |
B. | Toroid and writhe |
C. | Twist and wrap |
D. | Twist and crossover |
Answer» B. Toroid and writhe | |
8. |
Linking number is always a ___________ |
A. | Whole number |
B. | Prime number |
C. | Integer |
D. | Even number |
Answer» D. Even number | |
9. |
Passing of one strand through the other in order to get separated is known as _______ |
A. | Twist |
B. | Linking number |
C. | Writhing number |
D. | Toroid |
Answer» C. Writhing number | |
10. |
The two strands of cccDNA can be easily separated without any breakage of bonds. |
A. | True |
B. | False |
Answer» C. | |