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This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
1. |
Nonsense mutation is also known as ___________ |
A. | Missense mutation |
B. | Frame shift mutation |
C. | Stop mutation |
D. | Reverse mutation |
Answer» D. Reverse mutation | |
2. |
Which of the following disease is caused by missense mutation? |
A. | Thalassemia |
B. | Sickle cell anemia |
C. | Hemophilia |
D. | Cystic fibriosis |
Answer» C. Hemophilia | |
3. |
The alterations that change a codon specific for one amino acid to a codon specific for another amino acid is known as ___________ |
A. | Missense mutation |
B. | Nonsense mutation |
C. | Frame shift mutation |
D. | Reverse Mutation |
Answer» B. Nonsense mutation | |
4. |
How many types of point mutations are able to alter the Genetic code? |
A. | 1 |
B. | 2 |
C. | 3 |
D. | 4 |
Answer» D. 4 | |
5. |
IREs for the process of translation is present in viruses. Their function resembles that of eukaryotic ribosome. |
A. | True |
B. | False |
Answer» C. | |
6. |
The initiation factors are closely associated with the 3 end of mRNA through the initiation between the eIF4F and the ___________ |
A. | Poly A tail |
B. | Poly A binding proteins |
C. | Small subunit of ribosome |
D. | Large subunit of ribosome |
Answer» C. Small subunit of ribosome | |
7. |
mRNA scanning is a cost-effective mechanism. |
A. | True |
B. | False |
Answer» B. False | |
8. |
Which of the following protein interacts with the eIF4F for recruiting the pre-initiation complex to the mRNA? |
A. | eIF1 |
B. | eIF2 |
C. | eIF3 |
D. | eIF4 |
Answer» D. eIF4 | |
9. |
Recognition of mRNA by 43S pre-initiation complex is mediated by the enzyme ___________ |
A. | eIF2-GTP |
B. | eIF4F |
C. | eIF5B-GTP |
D. | eIF1 |
Answer» C. eIF5B-GTP | |
10. |
Which of the following eukaryotic proteins is an analog of IF2-GTP? |
A. | eIF2B-GTP |
B. | eIF2-GTP |
C. | eIF5B-GTP |
D. | eIF4G |
Answer» D. eIF4G | |
11. |
The first amino acid to be incorporated in the eukaryotic polypeptide is ___________ |
A. | Methionine |
B. | Valine |
C. | N-formyl methionine |
D. | N-acyl valine |
Answer» B. Valine | |
12. |
The same number of auxiliary proteins is used to drive the initiation process of both prokaryotes and eukaryotes. |
A. | True |
B. | False |
Answer» C. | |
13. |
Eukaryotic mRNA generally codes for a single protein because the eukaryotic translation includes ____________ |
A. | A single ORF |
B. | Monocistronic codons |
C. | Polycistronic codons |
D. | Starts at the first triplet codon |
Answer» C. Polycistronic codons | |
14. |
The subunit association with the mRNA occurs before tRNA recruitment in the case of both eukaryotes and prokaryotes. |
A. | True |
B. | False |
Answer» C. | |