MCQOPTIONS
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MCQOPTIONS
This section includes 18 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following is the correct sequence of turnover? |
| A. | Exonucleolytic degradation, decapping, deadenylation |
| B. | Exonucleolytic degradation, deadenylation and decapping |
| C. | Deadenylation, decapping, exonucleolytic degradation |
| D. | Decapping, deadenylation and exonucleolytic degradation |
| Answer» D. Decapping, deadenylation and exonucleolytic degradation | |
| 2. |
Which of these is not an NMD factor? |
| A. | DCP1 |
| B. | Exonuclease |
| C. | EJC |
| D. | Ski 7 |
| Answer» C. EJC | |
| 3. |
The Stem loop structures at the 5’ UTR of Ferritin is not ______________ |
| A. | Binding to IRE-BP |
| B. | Regulation ferritin level |
| C. | Degraded when unbound |
| D. | Acting as iron sensor |
| Answer» D. Acting as iron sensor | |
| 4. |
In an experiment you delete a part of the 5’ UTR of transferring mRNA, what will be its effect on iron sensitivity? |
| A. | It will be able to sense iron changes better |
| B. | It will not be able to sense the iron changes |
| C. | No change |
| D. | It will have leaky sensitivity |
| Answer» D. It will have leaky sensitivity | |
| 5. |
In a synergistic model of initiation which of the following factor doesn’t directly lead to initiation? |
| A. | eIF4E |
| B. | PAB1 |
| C. | eIF4G |
| D. | Protein X |
| Answer» E. | |
| 6. |
In an experiment with the effect of insulin on the protein synthesis, which of the factors doesn’t play a role? |
| A. | RTK |
| B. | mTOR |
| C. | eIF4E |
| D. | eIF2B |
| Answer» E. | |
| 7. |
IN_AN_EXPERIMENT_YOU_DELETE_A_PART_OF_THE_5‚ÄÖ√Ñ√∂‚ÀÖ√Ë‚ÀÖ¬•_UTR_OF_TRANSFERRING_MRNA,_WHAT_WILL_BE_ITS_EFFECT_ON_IRON_SENSITIVITY??$# |
| A. | It will be able to sense iron changes better |
| B. | It will not be able to sense the iron changes |
| C. | No change |
| D. | It will have leaky sensitivity |
| Answer» D. It will have leaky sensitivity | |
| 8. |
Which of these is not an NMD factor?$ |
| A. | DCP1 |
| B. | Exonuclease |
| C. | EJC |
| D. | Ski 7 |
| Answer» C. EJC | |
| 9. |
The_Stem_loop_structures_at_the_5’_UTR_of_Ferritin_is_not_______________$# |
| A. | Binding to IRE-BP |
| B. | Regulation ferritin level |
| C. | Degraded when unbound |
| D. | Acting as iron sensor |
| Answer» D. Acting as iron sensor | |
| 10. |
Which_of_the_following_is_the_correct_sequence_of_turnover? |
| A. | Exonucleolytic degradation, decapping, deadenylation |
| B. | Exonucleolytic degradation, deadenylation and decapping |
| C. | Deadenylation, decapping, exonucleolytic degradation |
| D. | Decapping, deadenylation and exonucleolytic degradation |
| Answer» D. Decapping, deadenylation and exonucleolytic degradation | |
| 11. |
Translation of which sigma factor is dependent on a genetic thermostat? |
| A. | Sigma 70 |
| B. | Sigma 32 |
| C. | Sigma E |
| D. | Sigma S |
| Answer» C. Sigma E | |
| 12. |
In an experiment if you take a stretch of hybridized RNA, and add only eIF4A, eIF4B and eIF4a and eIF4B together what will happen to the band obtained by that fragment under SDS. |
| A. | Slight rise, no rise, appearance of two bands one on top of original |
| B. | No rise in all cases but appearance of a 2<sup>nd</sup> band on top of 1<sup>st</sup> in 3<sup>rd</sup> case |
| C. | Slight rise, slightly more rise, and highest rise |
| D. | A faint band above the original, only original and a dark band above original |
| Answer» E. | |
| 13. |
The production of casein by rat mammary gland tissue reduces 100 fold in the absence of prolactin hormone. This reduction is due to_____________ |
| A. | Binding of eIF4E by PHAS 1 |
| B. | Greater turnover of mRNA for casein |
| C. | Lesser synthesis of casein mRNA |
| D. | Development of secondary structure on mRNA preventing translation |
| Answer» C. Lesser synthesis of casein mRNA | |
| 14. |
When the intracellular iron level is low, the turnover of transferrin mRNA is________ |
| A. | Increased |
| B. | Decreased |
| C. | Kept normal |
| D. | Doesn’t effect |
| Answer» C. Kept normal | |
| 15. |
In a synergistic model of initiation which of the following factor doesn’t directly lead to initiation?$ |
| A. | eIF4E |
| B. | PAB1 |
| C. | eIF4G |
| D. | Protein X |
| Answer» E. | |
| 16. |
Which of the following acts as a GAP during translation? |
| A. | eIF2B |
| B. | eIF4F |
| C. | eIF1a |
| D. | eIF5B |
| Answer» E. | |
| 17. |
In an experiment with the effect of insulin on the protein synthesis, which of the factors doesn’t play a role?$ |
| A. | RTK |
| B. | mTOR |
| C. | eIF4E |
| D. | eIF2B |
| Answer» E. | |
| 18. |
Mitogens can control translation efficiency by acting on _____________ factor which ___________ |
| A. | eIF4 factors which increases translation |
| B. | eIF4A factors which decreases translation |
| C. | eIF4E factors which increases translation |
| D. | eIF4G factors which decreases translation |
| Answer» D. eIF4G factors which decreases translation | |