Explore topic-wise MCQs in Cytogenetics.

This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Cytogenetics knowledge and support exam preparation. Choose a topic below to get started.

1.

During Strisinger’s model, what happens?

A. The Ribosome slips which causes duplication
B. Parent strand slippage polymerase
C. Daughter strand slippage polymerase
D. The polymerase back tracks and resynthesizes
Answer» D. The polymerase back tracks and resynthesizes
Discussion
2.

If a gene undergoes duplication and one of the duplicated copy is mutated to render unexpressed protein. What will be the effect on phenotype?

A. Mutant phenotype
B. Normal phenotype
C. Expression of the mutant gene is less than that would occur if both copy active
D. The gene not expressed at all
Answer» C. Expression of the mutant gene is less than that would occur if both copy active
Discussion
3.

Which human chromosomes are involved in Down’s syndrome?

A. 6
B. 14 and 21
C. 8 and 12
D. X and Y
Answer» C. 8 and 12
Discussion
4.

The Streisinger’s model explains__________

A. Frame shifts
B. Transposition
C. Inversion
D. Transition
Answer» B. Transposition
Discussion
5.

Tandem duplication creates ____________ and reverse tandem creates_____________

A. Buckling, looping
B. Hairpin, buckling
C. Buckling, Hairpin
D. Loop with turn, hairpin
Answer» D. Loop with turn, hairpin
Discussion
6.

IF_A_GENE_UNDERGOES_DUPLICATION_AND_ONE_OF_THE_DUPLICATED_COPY_IS_MUTATED_TO_RENDER_UNEXPRESSED_PROTEIN._WHAT_WILL_BE_THE_EFFECT_ON_PHENOTYPE??$

A. Mutant phenotype
B. Normal phenotype
C. Expression of the mutant gene is less than that would occur if both copy active
D. The gene not expressed at all
Answer» C. Expression of the mutant gene is less than that would occur if both copy active
Discussion
7.

During_Strisinger’s_model,_what_happens?$#

A. The Ribosome slips which causes duplication
B. Parent strand slippage polymerase
C. Daughter strand slippage polymerase
D. The polymerase back tracks and resynthesizes
Answer» D. The polymerase back tracks and resynthesizes
Discussion
8.

Which of the following could be due to duplication?

A. Co-dominance
B. Dominance
C. Incomplete dominance
D. Pleiotropy
Answer» E.
Discussion
9.

Which human chromosomes are involved in Down’s syndrome?$

A. 6
B. 14 and 21
C. 8 and 12
D. X and Y
Answer» C. 8 and 12
Discussion
10.

Duplication of Vermillion eye colour gene leads to the expression of the mutant phenotype. Which of the following can lead to normal phenotype with this duplication present?

A. Reverse tandem duplication
B. Duplication of normal eye colour gene
C. Deletion of both the Vermillion gene
D. Translocation of Vermillion gene to another chromosome
Answer» C. Deletion of both the Vermillion gene
Discussion
11.

Which of the following will have the highest number of eye facete?

A. Ultra bar female Drosophila
B. Heterozygous Bar male Drosophila
C. Heterozygous Bar female Drosophila
D. Homozygous bar Female
Answer» D. Homozygous bar Female
Discussion
12.

If there are two sequences CGCGCGCG and ATATATAT, which will have a higher probability of being duplicated?

A. ATATATATAT
B. CGCGCGCGCG
C. Both will have equal probability
D. Both are unlikely to be duplicated
Answer» D. Both are unlikely to be duplicated
Discussion
13.

The Streisinger’s model explains__________$

A. Frame shifts
B. Transposition
C. Inversion
D. Transition
Answer» B. Transposition
Discussion
14.

Tandem duplication creates ____________ and reverse tandem creates_____________

A. Buckling, looping
B. Hairpin, buckling
C. Buckling, Hairpin
D. Loop with turn, hairpin
Answer» D. Loop with turn, hairpin
Discussion
15.

Which of the following case of duplication involves more than one chromosome?

A. Tandem duplication
B. Reverse tandem duplication
C. Displaced
D. Transposed
Answer» E.
Discussion