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This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Protein Engineering knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
How many combinations of dipeptides can be formed if four solutions of different amino-acids are mixed? |
| A. | Four |
| B. | Six |
| C. | Eight |
| D. | Sixteen |
| Answer» E. | |
| 2. |
The side group of arginine is protected by which of the following protecting groups? |
| A. | A triphenylmethyl group (Trt) |
| B. | A tertiary butyl group (tBu) |
| C. | A tertiarybutyloxycarbonyl (tBOC) |
| D. | 2,2,5,7,8-pentamethylchroman-6-sulphonyl group (PMC) |
| Answer» E. | |
| 3. |
How many combinations of tetrapeptides can be formed if three solutions of different amino-acids are mixed? |
| A. | Ninety-one |
| B. | Eighty-six |
| C. | Seventy-two |
| D. | Eighty-one |
| Answer» E. | |
| 4. |
If the yield for each amino acid addition in SPPS is 99.99 % then, what will be the overall yield of a 50 amino acid peptide? |
| A. | 98.2 % |
| B. | 99.1 % |
| C. | 99.9 % |
| D. | 99.5 % |
| Answer» E. | |
| 5. |
Once the synthesis of the peptide is complete, it is removed from the polyamide with the help of which reagent? |
| A. | 1,3-dicyclohexylcarbodiimide |
| B. | Piperidine |
| C. | Fluorobenzene |
| D. | Trifluoroacetic acid |
| Answer» E. | |
| 6. |
How many combinations of tripeptides can be formed if three solutions of different amino-acids are mixed? |
| A. | Twenty-four |
| B. | Nine |
| C. | Sixteen |
| D. | Twenty-seven |
| Answer» E. | |
| 7. |
The side group of lysine is protected by which of the following protecting groups? |
| A. | A tertiary butyl group (tBu) |
| B. | A triphenylmethyl group (Trt) |
| C. | 2,2,5,7,8-pentamethylchroman-6-sulphonyl group (PMC) |
| D. | A tertiarybutyloxycarbonyl (tBOC) |
| Answer» E. | |
| 8. |
How many combinations of tetrapeptides can be formed if two solutions of different amino-acids are mixed? |
| A. | Twelve |
| B. | Nine |
| C. | Twenty-four |
| D. | Sixteen |
| Answer» E. | |
| 9. |
If the yield for each amino acid addition in SPPS is 99 % then, what will be the overall yield of a 40 amino acid peptide? |
| A. | 64.1 % |
| B. | 76.8 % |
| C. | 86.9 % |
| D. | 66.9 % |
| Answer» E. | |
| 10. |
The side group of cysteine is protected by which of the following protecting groups? |
| A. | 2,2,5,7,8-pentamethylchroman-6-sulphonyl group (PMC) |
| B. | A tertiary butyl group (tBu) |
| C. | A tertiarybutyloxycarbonyl (tBOC) |
| D. | A triphenylmethyl group (Trt) |
| Answer» E. | |
| 11. |
How many combinations of tripeptides can be formed if two solutions of different amino-acids are mixed? |
| A. | Twelve |
| B. | Sixteen |
| C. | Thirty-two |
| D. | Eight |
| Answer» E. | |
| 12. |
In the deprotection step of SPPS, the FMOC group is removed with the help of which of the following reagent? |
| A. | Fluorobenzene |
| B. | Trifluoroacetic acid |
| C. | 1,3-dicyclohexylcarbodiimide |
| D. | Piperidine |
| Answer» E. | |
| 13. |
The coupling reaction in the SPPS is catalyzed by which of the following? |
| A. | 1,4-dicyclohexylcarbodiimide |
| B. | 2,3-dicyclohexylcarbodiimide |
| C. | 1,2-dicyclohexylcarbodiimide |
| D. | 1,3-dicyclohexylcarbodiimide |
| Answer» E. | |
| 14. |
The side group of serine is protected by which of the following protecting groups? |
| A. | A tertiarybutyloxycarbonyl (tBOC) |
| B. | 2,2,5,7,8-pentamethylchroman-6-sulphonyl group (PMC) |
| C. | A triphenylmethyl group (Trt) |
| D. | A tertiary butyl group (tBu) |
| Answer» E. | |
| 15. |
What is the total number of dipeptides and tripeptides that can be formed when two solutions of different amino acids are mixed? |
| A. | Twenty-four |
| B. | Sixteen |
| C. | Ten |
| D. | Twelve |
| Answer» E. | |